2018 American Transplant Congress
Prevention of an Adaptive Immune Response by FDA-Approved Immunosuppressive Agents in Baboons with Pig Artery Patch Xenografts
Background: In the pig-to-baboon artery patch model with no immunosuppressive therapy, a graft from a GTKO pig elicits a significant anti-nonGal IgG response, indicating sensitization…2018 American Transplant Congress
Induction Agents and Post-Transplant Malignancies in Kidney Transplants: An Examination of Outcomes at a Large Volume Center over 20 Years
Division of Transplant Surgery, University of Wisconsin, Madison, WI.
Introduction: Induction agents have a profound effect on the immune milieu at the time of kidney transplantation. However, evaluation of their long-term effects on graft…2018 American Transplant Congress
Ten Year Follow-Up of Islet Recipients on Anti-LFA1 Therapy: Over-Immunosuppression Leads to Operational Tolerance?
Introduction: Ten-year outcomes from a cohort of five pre-uremic islet transplant (txp) recipients treated with anti-leukocyte functional antigen-1 (LFA-1) antibody Efalizumab (EFA) revealed two patients…2018 American Transplant Congress
Contemporary Desensitization with Low Dose Rituximab Ensures Kidney Transplant Outcome beyond ABO Blood Type Incompatibility:A Comparison between past Regimens in Single Institute
Kidney Transplant Surgery and Urology, Sapporo City General Hospital, Sapporo, Japan.
INTRODUCTION: An ABO incompatible kidney transplant (ABOiKT) requires desensitization (DS). The ways of DS have been changed chronologically and the outcome could have been subsequently…2018 American Transplant Congress
Experience with Alemtuzumab Induction with Tacrolimus/Mycophenolate +/- Steroids in Simultaneous Pancreas-Kidney Transplant Recipients with Portal-Enteric Drainage
Surgery, Medicine, Pathology, Pharmacy, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Introduction: Simultaneous pancreas-kidney transplant (SPKT) recipients are a relatively homogeneous population that are considered high immunological risk because of younger age, presumed autoimmune etiology of…2018 American Transplant Congress
Lack of Efficacy of Eculizumab for Prevention of Delayed Graft Function (DGF) in Deceased Donor Kidney Transplant Recipients
DGF portends poor short- and long-term renal function, increases cost, and may reduce graft survival. We studied the safety/efficacy of eculizumab (ECU), a C5 convertase…2018 American Transplant Congress
Digital Health Education for the Pediatric Solid Organ Transplant Population
Background: Self-management and adherence are key factors that influence post transplant graft survival. Education after solid organ transplant plays an important role in providing patients…2018 American Transplant Congress
Early Steroid Withdrawal or Tacrolimus Minimization versus Standard Immunosuppression in Renal Transplant Recipients: The Allegro Trial
BackgroundCurrent immunosuppressive regimen in most renal transplant recipients (RTR) combines basiliximab induction with tacrolimus, mycophenolic acid and prednisolone maintenance therapy. Reduction of immunosuppression by withdrawal…2018 American Transplant Congress
Evaluation of Multiple Linear Regression Limited Sampling Strategies for Enteric-Coated Mycophenolate Sodium in Adult Kidney Transplant Recipients
Background: Although multiple linear regression-based limited sampling strategies (LSS) have been published for enteric-coated mycophenolate sodium none have been evaluated for prediction of subsequent mycophenolic…2018 American Transplant Congress
mTOR Inhibitor Based Immunosuppression Regimens Are Not Associated with Lower Risk for BK Infection
Introduction: BK virus continues to be a significant post-transplant complication with increasing incidence in the current era of potent immunosuppression. Mammalian target of rapamycin inhibitors…
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