ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2019 American Transplant Congress

    Anti-Complement Component 5 Antibody Based Immunosuppression Induced Accommodation in ABO Incompatible Heart Transplantation

    S. Park1, S. Lee1, J. Hwang1, J. Ryu2, T. Koo2, C. Ahn3, J. Yang4

    1Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea, Republic of, 2Transplantation Center, Seoul National University Hospital, Seoul, Korea, Republic of, 3Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Republic of, 4Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of

    *Purpose: Plasmapheresis in combination with immunoglobulin and rituximab is often used to induce accommodation in ABO-incompatible (ABOi) living-donor transplantation; however, this regimen cannot be applied…
  • 2019 American Transplant Congress

    Racial Disparities in Documentation of Non-Adherence and Its Relation to Rejection in Pediatric Kidney Transplant Recipients

    T. Melanson, J. Hogan, K. Maroney, R. Patzer, R. George

    Emory University, Atlanta, GA

    *Purpose: Black patients have historically been disadvantaged throughout the transplant process. Many factors impact the success of kidney transplantation, but the need for strict adherence…
  • 2019 American Transplant Congress

    Assessing the Effectiveness of Early Maintenance Immunosuppression Practices in Liver Transplantation

    T. Bittermann, R. Hubbard, J. Lewis, D. Goldberg

    University of Pennsylvania, Philadelphia, PA

    *Purpose: Evidence regarding the efficacy of maintenance immunosuppression (IS) regimens for liver transplantation (LT) arise from clinical trials. However, the ‘real world’ effectiveness of such…
  • 2019 American Transplant Congress

    Prevalence of Non-Adherence to Immunosuppressive Medications in Kidney Transplant Recipients, Barriers and Predictors

    S. Taj1, H. Baghaffar2, D. Alnajjar2, N. Almashabi3, S. Ismail4

    1King Saud Bin Abdulaziz University For Health Sciences, Jeddah, Saudi Arabia, 2Ibn Sina College, Jeddah, Saudi Arabia, 3Umm Al-Qura University, Makkah, Saudi Arabia, 4Pharmaceutical Care Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia

    *Purpose: Non-adherence to immunosuppressant therapy (IST) is one of the major factors leading to graft rejection. To our knowledge, limited data exist on the prevalence…
  • 2019 American Transplant Congress

    Impact Of Selective Cd28 Blockade On Protective Immunity To A Murine Epstein-Barr Virus Homolog

    R. L. Crepeau, J. A. Elengickal, M. L. Ford

    Surgery, Emory University, ATLANTA, GA

    *Purpose: CTLA-4Ig blocks CD80/CD86, the ligands for both CD28 and CTLA-4. Thus, in addition to the intended effect of blocking CD28-mediated costimulation, CTLA4-Ig also has…
  • 2019 American Transplant Congress

    Infectious Complications in Tocilizumab-Treated Kidney Transplant Recipients

    S. Sethi, A. Peng, R. Najjar, A. Vo, S. Jordan, E. Huang

    Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: Tocilizumab blocks IL-6 signaling, inhibiting maturation of B cells to plasma cells and antibody production. We have used tocilizumab since 2012 to treat kidney…
  • 2019 American Transplant Congress

    Development of a Pharmacy Collaborative Practice Agreement to Improve Efficiency and Management of Prescribing in a Renal Transplant Clinic

    R. Chelewski1, K. Johnson1, A. Zuckerman2, J. DeClercq3, L. Choi3, M. Peter2, A. J. Langone4

    1Vanderbilt Specialty Pharmacy Services, Vanderbilt Univ Medical Ctr, Nashville, TN, 2Department of Pharmacy, Vanderbilt Univ Medical Ctr, Nashville, TN, 3Department of Biostatistics, Vanderbilt Univ Medical Ctr, Nashville, TN, 4Division of Nephrology, Vanderbilt Univ Medical Ctr, Nashville, TN

    *Purpose: This study describes the development of a Collaborative Pharmacy Practice Agreement (CPPA) between transplant pharmacists and physicians and assesses change in prescription volume and…
  • 2019 American Transplant Congress

    The Effect Of Tacrolimus Trough Variability On Kidney Transplant Outcomes

    S. Heeney1, K. R. Szempruch1, R. Lee1, A. Mintz2, P. Serrano1, R. Detwiler1, C. Doligalski1

    1University of North Carolina Medical Center, Chapel Hill, NC, 2University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC

    *Purpose: High variability in tacrolimus as assessed by tacrolimus coefficient of variability (TCV) in trough levels of kidney transplant recipients (KTRs) has been associated with…
  • 2019 American Transplant Congress

    Conversion to Belatacept in Kidney Transplant Recipients with Systemic Lupus Erythematosus

    I. Carrión Barberà, M. C. Fajardo, D. Tsapepas, J. Gartshteyn, A. Askanase, H. E. Fernandez

    Columbia University MC, New York, NY

    *Purpose: Lupus nephritis (LN) results in the need for renal replacement therapy (RRT) in 10-30% of LN pts and 30% receive a kidney transplant (KT).…
  • 2019 American Transplant Congress

    Patient Reported Side Effects Associated with Reduced Quality of Life after Living Donor Kidney Transplant

    J. Peipert, J. C. Caicedo-Ramirez, K. Ensor, J. Friedewald, M. Abecassis, D. Cella, D. Ladner, Z. Butt

    Northwestern University, Chicago, IL

    *Purpose: As living donor kidney transplant (LDKT) graft and patient survival approaches 100%, the focus of care turns to patient reported outcome measures such as…
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