ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2019 American Transplant Congress

    Anti-CD272 Antibody (6B2) Induced Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allograft

    E. Yin, M. Uchiyama, Y. Yamamoto, M. Niimi

    Teikyo University, Tokyo, Japan

    *Purpose: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA; CD272) has been implicated in the regulation of autoimmune and may potentially play an important…
  • 2019 American Transplant Congress

    The Impact of Acute Rejection in Heart Transplantation on Post-Transplant Malignancy

    K. Kamrani1, A. Okoh2, D. Hanos1, M. Camacho1, M. Zucker2, K. Clarke1

    1Dept. of Surgery, Newark Beth Israel Medical Center, Newark, NJ, 2Dept. of Medicine, Newark Beth Israel Medical Center, Newark, NJ

    *Purpose: Compared with the general population, an increased incidence of skin cancers and lymphomas have been shown in orthotopic heart transplant (OHT) recipients. However, the…
  • 2019 American Transplant Congress

    Frailty Associated with Increased Rates of Acute Cellular Rejection within 3 Months after Liver Transplantation

    L. Fozouni, A. Lebsack, Y. Mohamad, C. Freise, P. Stock, J. Lai

    UCSF, San Francisco, CA

    *Purpose: Frailty, a state of decreased physiologic reserve and increased vulnerability to health stressors, has an inflammatory biologic basis and has been associated with dysregulation…
  • 2019 American Transplant Congress

    The Evolving Clinical Presentation of Acute Rejection in Face Transplantation

    V. Haug, B. Kollar, D. Obed, H. Kiwanuka, M. Turk, L. Wo, S. Tasigiorgos, M. Kueckelhaus, L. Riella, B. Pomahac

    Plastic and Reconstructive Surgery, Brigham and Women's Hospital, Boston, MA

    *Purpose: Clinical signs such as erythema or edema are traditionally helpful to diagnose Acute rejection (AR) in face transplantation (FT) in the early follow-up. The…
  • 2019 American Transplant Congress

    Tacrolimus Concentrations Can Be Reliably Measured in Capillary Microsamples

    M. T. Gustavsen, N. Vethe, M. Lauritsen, A. Andersen, A. Åsberg, S. Bergan, K. Midtvedt

    Oslo University Hospital, Rikshospitalet, Oslo, Norway

    *Purpose: Routine therapeutic drug monitoring (TDM) of tacrolimus (Tac) is currently performed in venous bloods samples drawn at the hospital. The novel volumetric absorptive microsampling…
  • 2019 American Transplant Congress

    Immunosuppression after Organ Transplantation Does Not Enhance Patency of Cold-Stored Vein Allografts for Critical Limb Ischemia -Single Centre Experience

    J. Chlupac, T. Marada, R. Novotny, K. Lipar, L. Janousek, J. Fronek

    Transplant Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: Sub-inguinal bypass with cold-stored saphenous vein allograft is a last option treatment for extensive peripheral arterial occlusive disease with absent autologous vein. The aim…
  • 2019 American Transplant Congress

    Effect of Everolimus on IgM and IgG Memory B Cell Growth and Survival In Vitro and Applications for Effective Administration in Clinical Practice

    Y. Matsuda

    Osaka University Graduate School of Medicine, Osaka, Japan

    *Purpose: Everolimus (EVR), which is converted from CNI, is reported to improve renal function and reduce renal toxicity, DSA production, and rejection development. However, there…
  • 2019 American Transplant Congress

    Relationship between Comorbilities and Infectious Disease in Kidney Transplant Recipients Receiving Rituximab

    A. Molina-Andújar1, E. Hermida1, J. Rovira2, F. Cofan1, P. Ventura-Aguiar1, N. Esforzado1, V. Torregrosa1, D. Cucchiari1, E. de Souza1, I. Revuelta1, F. Oppenheimer1, F. Diekmann1, G. Piñeiro1

    1Renal Transplant Unit, Hospital Clínic de Barcelona, Barcelona, Spain, 2Laboratori Experimental de Nefrologia i Trasplantament, IDIBAPS, Barcelona, Spain

    *Purpose: Rituximab is commonly used in the context of kidney transplantation. Evidence about infectious complications and its relationship with predictive factors is scarce. The aim…
  • 2019 American Transplant Congress

    Blood Group Incompatible Living Donor Kidney Transplantation in Patients with End-Stage Kidney Disease Due to Diabetes Kidney Disease

    J. Uchida1, A. Kosoku1, K. Kabei1, S. Nishide1, H. Shimada1, K. Maeda2, Y. Yoshikawa3, T. Iwai1, N. Kuwabara1, T. Naganuma1, N. Kumada4, Y. Takemoto1, T. Nakatani1

    1Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, 2Nursing, Osaka City University Hospital, Osaka, Japan, 3Osaka City University, Osaka, Japan, 4Urology, Suita Municipal Hospital, Suita, Japan

    *Purpose: Diabetes is a growing public health problem, and diabetes kidney disease (DKD) is the most prevalent chronic kidney disease and the major cause of…
  • 2019 American Transplant Congress

    Neutralization of Interlukin-6 by ALD518-P18 (Murine Clazakizumab) Attenuates Donor Specific Antibody Responses in a Mouse Model of Allogeneic Sensitization: A Report of Dosage Finding Study

    I. Kim, G. Wu, N. Chai, T. Brennan, A. Klein, S. Jordan

    Cedars-Sinai Med Ctr, Los Angeles, CA

    *Purpose: Interleukin-6 (IL-6) is a proinflammatory cytokine involved in mediating both T-cell and B-cell responses in allograft rejection. In previous studies, we demonstrated that inhibition…
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