2019 American Transplant Congress
Impact of Granulocyte Colony Stimulating Factor on Clinical Outcomes in Kidney Transplant Recipients with Neutropenia
*Purpose: Neutropenia, defined as an absolute neutrophil count (ANC)2019 American Transplant Congress
Safety and Efficacy of Peri-Operative Sublingual Tacrolimus in Pancreas Transplant as Compared to Oral Tacrolimus
*Purpose: Early post-transplant, use of oral or enteral medications in pancreas transplant (PTX) is difficult due to NG tubes put to suction. The use of…2019 American Transplant Congress
Development and Validation of a Capillary Blood Mitra-Based Assay for the Quantitative Determination of Advagraf® Concentrations in Transplant Patients
*Purpose: Therapeutic drug monitoring of tacrolimus (TAC) requires venepuncture blood samples taken by specialists, requiring patients to attend an outpatient clinic; this can be inconvenient…2019 American Transplant Congress
Technology Triggered Adherence Intervention – Preliminary Findings
1University of Cincinnati, Cincinnati, OH, 2UC Health, Cincinnati, OH
*Purpose: Medication non-adherence (M-NA) after renal transplant (RT) increases the risk of graft failure. We conducted a prospective, randomized, single center trial to evaluate 3…2019 American Transplant Congress
Resolution of Hyperglycemia Following Islet Allograft Transplantation in Non-Immunosuppressed Mice
*Purpose: Kidney allografts are naturally tolerogenic in mice. Certain mouse strain combinations develop tolerance of kidney allografts across full MHC incompatibilities without immunosuppression (e.g. DBA/2…2019 American Transplant Congress
Age-Related Effects on Thymic Output and Homeostatic T Cell Expansion Following Depletional Induction
Surgery, Duke University, Durham, NC
*Purpose: Alemtuzumab induction leads to profound T cell depletion followed by a prolonged period of repopulation. Repopulation is thought to be influenced both by thymic…2019 American Transplant Congress
Race-Sex Effects on Immune Response Potential during Tacrolimus Minimization Therapy in Stable Renal Allograft Recipients
*Purpose: African American renal transplant recipients (RTR) exhibit more immunoreactivity to allografts which may contribute to chronic rejection. This study investigated race-sex influences on ex…2019 American Transplant Congress
Combination of Extended-Release Tacrolimus Plus Everolimus Once Daily in De Novo Kidney Transplant Recipients: ER-Tac vs LCPT
Surgery, Renal Transplant Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
*Purpose: Combination of Everolimus (EVR) with Tacrolimus (Tac) permits reduced calcineurin inhibitors exposure and, recently, has been demonstrated safe and effective. Two different once-daily Tacrolimus…2019 American Transplant Congress
CCR5-Mediated Recruitment of NK Cells to the Kidney is a Critical Step for Host Defense to Candida albicans Infection
*Purpose: Candida albicans infection causes a high rate of mortality in immunocompromised or transplant patients. In this study, we investigated the role of CCR5 that…2019 American Transplant Congress
Approach to Leukopenia in Older Kidney Transplant Recipients
Dept of Medicine, Medical University of South Carolina, Charleston, SC
*Purpose: Older kidney transplant recipients face challenges of post-transplant complications related to frailty and comorbidity burden. They are particularly vulnerable to side effects of immunosuppression…
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