2019 American Transplant Congress
What’s in a High Dose? An Analysis of Tacrolimus Pharmacokinetic Parameters in Rapid Metabolizers
*Purpose: CYP3A5*1 expressers exhibit differences in immediate-release tacrolimus (IR-Tac) PK and require higher doses of IR-Tac to maintain therapeutic trough concentrations. LCP-Tacrolimus (LCPT) demonstrates a…2019 American Transplant Congress
Tocilizumab for Refractory Antibody-Mediated Rejection in Pediatric Kidney Transplantation
University of California, Los Angeles, Los Angeles, CA
*Purpose: IL-6 blockade may play a role in reducing human leukocyte antigen donor specific antibodies (HLA DSA) production and stabilizing allograft function. We aimed to…2019 American Transplant Congress
Effect of ATG on Monocytic Myeloid-Derived Suppressor Cells and Its Associated Mechanisms in Kidney Transplantation Recipients
Beijing Chao-yang Hospital, Beijing, China
*Purpose: Myeloid-derived suppressor cells (MDSCs) consist of heterogeneous myeloid progenitors and precursors that was first defined in cancer patients and are characterized by a immunoregulatory…2019 American Transplant Congress
Efficacy of Belatacept Conversion Protocols
Kaiser Los Angeles Medical Center, Los Angeles, CA
*Purpose: Belatacept (bela) is approved for de novo use in kidney transplantation. Conversion from CNI to bela is utilized for various reasons. Conversion is off-label…2019 American Transplant Congress
Abatacept as Rescue Immunosuppression after Calcineurin Inhibitor Treatment Failure in Renal Transplantation
Emory University School of Medicine, Atlanta, GA
*Purpose: A majority of kidney transplant recipients receive calcineurin inhibitor (CNI)-based immunosuppression. However, some do not tolerate CNIs and require other immunosuppressive strategies. Until recently,…2019 American Transplant Congress
Urinary Biomarkers of Kidney Injury in Liver Transplant Recipients with Calcineurin Inhibitors Based Immunosuppression
1UTHSC, Memphis, TN, 2Transplant Institute, Memphis, TN
*Purpose: Renal dysfunction post solid organ transplantation is common and associated with several risk factors. Messenger RNA encoding for genes expressed along the nephron and…2019 American Transplant Congress
A Cluster of Late Onset of Pneumocystis jirovecii Pneumonia (PJP) in Renal Transplant Patients: First Cluster Report from Saudi Arabia
King Fahad specialist hospital - Dammam, Dammam, Saudi Arabia
*Purpose: Pneumocystis jiroveci pneumonia (PJP) is a serious opportunistic infection that can be associated with severe pulmonary involvement in transplant population. Post-transplant protocol at our…2019 American Transplant Congress
Risk Factors for Sensitization in the Failing Allograft: A Multi-Center Experience
*Purpose: Sensitization is frequent after an allograft fails and makes re-transplant difficult for many patients.*Methods: We performed a cross-sectional chart review of patients who were…2019 American Transplant Congress
Impact of Granulocyte Colony Stimulating Factor on Clinical Outcomes in Kidney Transplant Recipients with Neutropenia
*Purpose: Neutropenia, defined as an absolute neutrophil count (ANC)2019 American Transplant Congress
Safety and Efficacy of Peri-Operative Sublingual Tacrolimus in Pancreas Transplant as Compared to Oral Tacrolimus
*Purpose: Early post-transplant, use of oral or enteral medications in pancreas transplant (PTX) is difficult due to NG tubes put to suction. The use of…
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