ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2019 American Transplant Congress

    Impact of Steroid-Free Protocol on Incidence of Posttransplantation Diabetes Mellitus: A Prospective, Randomized, Multicenter, Open-Label, Controlled Trial in Renal Transplant Recipients

    J. Ekberg1, S. Baid-Agrawal1, B. Jespersen2, R. Källén3, E. Rafael3, K. Skov2, P. Lindnér1

    1Institute of Clinical Sciences, Transplant Institute, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden, 2Department of Nephrology, Aarhus University Hospital, Aarhus, Denmark, 3Department of Transplantation, Skane University Hospital, Malmoe, Sweden

    *Purpose: Comparison of two immunosuppressive protocols, steroid-free with antithymocyte globulin (ATG) induction, and steroid containing with basiliximab induction, regarding the incidence of PTDM, one year…
  • 2019 American Transplant Congress

    Impact of Belatacept Conversion on Renal Function, Histology and Gene Expression in Kidney Transplant Patients with Interstitial Fibrosis and Tubular Atrophy

    G. Gupta1, D. Kumar1, M. Raynaud2, A. Loupy2, J. Chang3, J. Reeve3, P. Sanghi1, I. Yakubu1, L. Kamal1, M. Levy1, C. Bhati1, P. Kimball1, A. King1, H. Massey1, P. Halloran3

    1Virginia Commonwealth University, Richmond, VA, 2Paris Transplant Group, Paris, France, 3Alberta Transplant Genomics Applied Centre, Edmonton, AB, Canada

    *Purpose: Prior studies on the conversion of tacrolimus (Calcineurin Inhibitor; CNI) to belatacept have been limited in scope due to either the absence of, post-conversion…
  • 2019 American Transplant Congress

    A Randomized Controlled Clinical Trial of Thymoglobulin® and Extended Delay of Calcineurin Inhibitor Therapy for Renal Protection after Liver Transplantation: A Multicenter Study

    L. Coromina1, S. Shah2, B. Xervos3, M. Zimmerman4, K. Sasaki1, T. Diago1, K. Hashimoto1, F. Aucejo1, m. Fujiki1, H. Block-Beach1, A. Patterson2, C. Miller1, C. Quintini1, B. Eghtesad1

    1The Cleveland Clinic, Cleveland, OH, 2University of Cincinnati, Cincinnati, OH, 3The Cleveland Clinic, Weston, FL, 4Medical College of Wisconsin, Milwaukee, WI

    *Purpose: Thymoglobulin® (r-ATG) has been used as induction therapy in liver transplantation (LT). No prospective, randomized, controlled, trial (RCT) has been performed to evaluate effect…
  • 2019 American Transplant Congress

    The Impact of Calcineurin Inhibitors on De Novo DSA in Primary Kidney Transplantation

    T. Hiramitsu, T. Tomosugi, K. Futamura, M. Okada, M. Tsujita, T. Ichimori, N. Goto, S. Narumi, Y. Watarai

    Nagoya Daini Red Cross Hospital, Nagoya Aichi, Japan

    *Purpose: De novo DSA was demonstrated as a cause of chronic AMR, leading to worse graft survival. New strategies to treat chronic AMR have been…
  • 2019 American Transplant Congress

    Everolimus/Low Tacrolimus Exposure versus Sodium Mycophenolate/Standard Tacrolimus for the Elderly Kidney Transplant Recipient. A 4-y Follow-Up of the nEverOld Trial

    E. David-Neto, F. Agena, F. J. Paula, N. Z. Galante, D. S. David, F. Ramos, A. K. Triboni, P. Romano, P. A. Ebner, V. Coelho, M. Altona, R. Falci, A. Piovesan, W. C. Nahas

    Renal Transplantation Service, Hospital das Clínicas - University of São Paulo School of Medicine, Sao Paulo, Brazil

    *Purpose: The standard immunosuppressive regimen used for younger patients may not be adequate for the elderly cohort.*Methods: The nEverOld is a prospective, single-center, randomized trial…
  • 2019 American Transplant Congress

    Early Rejection Outcomes with IL-2 vs. ATG Induction among Kidney Transplant Recipients Induction Differences with Early Steroid Withdrawal

    C. Burelli, A. Szczepanik, K. Yadav, E. Sanchez, M. Debroy, V. Humphreville, J. Rabets, A. Padiyar, N. Sarabu, A. Jittirat, A. Palanisamy, K. Chavin

    University Hospitals Cleveland Medical Center, Cleveland, OH

    *Purpose: Early steroid withdrawal in kidney transplant (Ktx) patients is controversial and has demonstrated an increased risk of acute rejection with similar long-term outcomes. Data…
  • 2019 American Transplant Congress

    Alemtuzumab versus Antithymocyte Globulin Induction Immunosuppression in Highly Sensitized Kidney Transplant Recipients

    A. Brueckner1, E. Yanqui1, C. Truong1, R. Baliga2, L. Bowman1

    1Tampa General Hospital, Tampa, FL, 2Florida Kidney Physicians, Tampa, FL

    *Purpose: Lymphocyte depleting agents such as rabbit anti-thymocyte globulin (rATG) and alemtuzumab are used for induction in highly sensitized (PRA ≥30%) kidney transplant recipients (KTRs).…
  • 2019 American Transplant Congress

    Association of Histological Findings in Renal Graft Biopsy with Non-Adherence to Immunosuppressive Treatment

    B. D. Cardoso1, J. Montagner2, K. Pegas3, R. Kist4, J. Neumann5, H. S. Pinheiro6, V. D. Garcia4, E. Keitel1

    1Department of Nephrology and Kidney Transplantation/ Post Graduation Program in Pathology, Irmandade Santa Casa de Misericórdia/ Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil, 2Transplant Immunology Laboratory,, Irmandade Santa Casa de Misericórdia, Porto Alegre, Brazil, 3Department of Pathology, Irmandade Santa Casa de Misericórdia, Porto Alegre, Brazil, 4Department of Nephrology and Kidney Transplantation, Irmandade Santa Casa de Misericórdia, Porto Alegre, Brazil, 5Transplant Immunology Laboratory, Irmandade Santa Casa de Misericórdia, Porto Alegre, Brazil, 6Renal Transplant Unit, NIEPEN/NIDEAL (UFJF), Porto Alegre, Brazil

    *Purpose: Non-adherence to immunosuppressive treatment after renal transplantation is a frequent issue, but the magnitude of its impact has been debated. It is unknown whether…
  • 2019 American Transplant Congress

    How Well Do Kidney Transplant Patients Understand Their Medications and Does Real-Time Assessment of Knowledge Improve Retention of Information?

    B. Clark1, B. Sirandas1, T. Larson2, A. Carlson1, C. Truax1, D. D. Ramirez1, L. Smith1, I. Hall1

    1University of Utah Health, Salt Lake City, UT, 2Henry Ford Hospital, Detroit, MI

    *Purpose: This study aims to evaluate the impact that early formal assessment and reteaching have on patient medication knowledge after renal transplant.*Methods: This was a…
  • 2019 American Transplant Congress

    Clinical Utility of a Pharmacogenomic Testing Tool among Kidney Transplant Recipients

    S. LeCorchick, L. Lindberg, W. Stapley, S. Anand, D. Morris, T. Srinivas

    Kidney/Pancreas Transplant Program, Intermountain Medical Center, Murray, UT

    *Purpose: Therapeutic drug monitoring (TDM) for tacrolimus (Tac) is the cornerstone of clinical workflow in the transplant clinic. We report on the clinical implementation of,…
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