2019 American Transplant Congress
Use of Eculizumab for Active Antibody-Mediated Rejection That Occurs Early Post-Kidney Transplantation: A Consecutive Series of 15 Cases
*Purpose: Active antibody-mediated rejection (ABMR) that occurs during the amnestic response within the first month post-transplant is a rare but devastating cause of early allograft…2019 American Transplant Congress
Transplant Regimen Adherence For Kidney Recipients By Engaging Information Technologies: The Take It Trial
*Purpose: Several studies report a high prevalence of inadequate adherence to prescribed (Rx) immunosuppressive (IS) medication regimens among kidney transplant (KT) recipients, yet few interventions…2019 American Transplant Congress
Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection in Solid Organ Transplant Recipients at an Academic Medical Center
Center for Transplantation, University of California, San Diego Health System, La Jolla, CA
*Purpose: In the United States, the incidence of Clostridium difficile infection (CDI) has increased remarkably and remains a significant burden in the solid organ transplant…2019 American Transplant Congress
Impact of Liver Recipient Genotype on Tacrolimus
*Purpose: In kidney transplant recipients, recipient genotype (CYP3A5 *3) has the greatest influence on tacrolimus pharmacokinetics (PK). However, in liver transplant recipient, donor liver and…2019 American Transplant Congress
Is Alemtuzumab Induction Safe In Septuagenarians Undergoing Deceased Donor Kidney Transplantation?
Wake Forest Baptist Medical Center, Winston-Salem, NC
*Purpose: Alemtuzumab induction in septuagenarians is controversial but understudied.*Methods: Single center retrospective review of adult deceased donor kidney transplant (KT) recipients receiving single dose (30…2019 American Transplant Congress
CYP3A5 Genotype Had No Influence on Renal Function after Renal Transplantation
*Purpose: Tacrolimus metabolism rate has been reported to be associated with renal function after renal transplantation (Thölking et al., 2014); this study aimed to determine…2019 American Transplant Congress
A Retrospective Observational Analysis of Tacrolimus Metabolism Rate: No Evidence for Impact on Renal Function
*Purpose: A previous publication found that fast metabolisers of tacrolimus had inferior renal function compared to slow metabolisers in a Caucasian population (Thölking et al.,…2019 American Transplant Congress
Impact of a Novel Digital Medicine Program on Adherence and Utilization in Pediatric Transplant Patients
*Purpose: Purpose: Optimal allograft function and long-term graft survival depends on many factors, including adherence to a complex medication regimen. Methods of measuring adherence are…2019 American Transplant Congress
Prevalence of Varicella Zoster Infection in Renal Transplant Recipients
Infectious Diseases, UCLA, Los Angeles, CA
*Purpose: Varicella zoster infection is a serious complication of immunosuppression in renal transplant recipients. We examined the prevalence of VZV infection in renal transplant patients…2019 American Transplant Congress
Combination of Ketoconazole and Tacrolimus Increases the Risk of Kidney Transplant Rejection in African Americans
Nephrology, Tulane University, New Orleans, LA
*Purpose: African American patients generally have a rapid metabolism and thus require higher doses of tacrolimus after kidney transplantation. Ketoconazole inhibits tacrolimus metabolism and can…
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