2020 American Transplant Congress
Ten Year Results of a Single Center Study of Rabbit Anti-Thymocyte Globulin Compared to Alemtuzumab Induction in Simultaneous Pancreas-Kidney Transplantation
Abdominal Transplant Surgery, Wake Forest Baptist Health, Winston Salem, NC
*Purpose: The study purpose was to analyze 10-year outcomes of depleting antibody induction agents in simultaneous pancreas-kidney transplant (SPKT) at a single center*Methods: From 2/02…2020 American Transplant Congress
New-Onset Diabetes after Adult Liver Transplantation in the Korean Organ Transplantation Registry Study
*Purpose: New-onset diabetes after transplantation (NODAT) is a serious complication following liver transplantation (LT). The present study aimed to investigate the incidence of and risk…2020 American Transplant Congress
ESAT-6, A Novel Protein Originally Produced by M. Tuberculosis, Inhibits Central Memory CD8+ T Cell Generation and Allograft Rejection
Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China
*Purpose: Allospecific memory T cells pose a threat to long-term allograft survival since they are somewhat resistant to immunosuppression. The objective of this study is…2020 American Transplant Congress
Management of Adenovirus Enteritis after Intestinal Transplantation
*Purpose: Solid organ transplant recipients are at risk for infection, in part due to immunosuppression. Adenovirus enteritis (AE) is one possible clinical presentation of infection…2020 American Transplant Congress
Treg Use PD-1 for Lymphatic Migration
*Purpose: Regulatory T cell (Treg) lymphatic migration is important for immune tolerance. Treg express both programmed death-1 (PD-1) and its ligand PD-L1, which are important…2020 American Transplant Congress
De Novo NAFLD Post-Liver Transplant is Defined by Altered Lipid Metabolism and Mitochondrial Dysfunction
*Purpose: De Novo Non-alcoholic Fatty Liver Disease (NAFLD) affects up to 35% of liver transplant (LT) recipients transplanted for non-NAFLD indications. Non-alcoholic steatohepatitis (NASH), the…2020 American Transplant Congress
Selective Dual Co-Stimulatory Blockade of CD28/CD80-86 and PD1-PL2 with a Novel Recombinant Bi-Specific Fusion Protein (Hybri-2) Promotes Successful Humoral Desensitization in a Stringent Sensitized Rat Model
*Purpose: Humoral Alloimmune memory is a main barrier for successful kidney transplantation and is orchestrated by a compartmentalized cellular immune response driven by bone-marrow LLPCs…2020 American Transplant Congress
Patterns of Belatacept Use and Risk of Post-Transplant Lymphoproliferative Disorder (PTLD) in US Kidney Transplant Recipients – Analysis of Organ Procurement and Transplantation Network (OPTN) Database
1United Network for Organ Sharing (UNOS), Richmond, VA, 2Bristol-Myers Squibb, Princeton, NJ
*Purpose: Belatacept, a selective T-cell costimulation blocker, was approved in 2011 for the prophylaxis of organ rejection in Epstein-Barr virus (EBV)-seropositive kidney transplant recipients. PTLD…2020 American Transplant Congress
Daily Immunosuppression to Combat Compliance in Adolescent Kidney Transplant
1Surgery, Stanford University, Stanford, CA, 2Pediatrics, Stanford University, Stanford, CA
*Purpose: Medication compliance remains a persistent, multifactorial problem in adolescent renal transplant recipients. Improving adherence in this patient demographic would benefit long-term patient and graft…2020 American Transplant Congress
Late Pneumocystis Jirovecii Pneumonia Often Misdiagnosed
*Purpose: Since 2/2018, we have identified 60 transplant recipients presenting with late PCR confirmed Pneumocystis jirovecii (PJP). Of this initial group, 17 kidney transplant recipients…
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