ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2020 American Transplant Congress

    Is it Time for Immune Screening for Belatacept-Treated Stable Kidney Transplant Patients for Adjust the Immunosuppression?

    M. C. Rial1, F. Caro2, N. Ambrosi2, D. Guerrieri2, A. Calleri1, E. Chuluyan1, D. Casadei1

    1ITAC, Buenos Aires, Argentina, 2CEFYBO, UBA, Buenos Aires, Argentina

    *Purpose: Belatacept is a co-stimulation blocker for primary maintenance immunosuppression in kidney transplant recipients. The goal of this work was to study the immunological status…
  • 2020 American Transplant Congress

    Incidence of Rejection One Year after Liver Transplantation Associated with Early versus Late Steroid Withdrawal

    S. Yun, L. Miko, J. Ahmad

    The Mount Sinai Hospital, New York, NY

    *Purpose: The adverse effects associated with steroid use make earlier steroid withdrawal desirable, but the optimal time for withdrawal after liver transplantation (LT) is not…
  • 2020 American Transplant Congress

    Perceived Barriers Are Associated with Immunosuppressive Medication Adherence among Japanese Kidney Transplant Recipients: A Cross-Sectional Study

    M. Takada1, K. Oda2, T. Kaitani2, M. Fujii2

    1The Graduate School of Nursing, Sapporo City University, Sapporo, Japan, 2School of Nursing, Sapporo City University, Sapporo, Japan

    *Purpose: Nonadherence to immunosuppressive medication after kidney transplantation is associated with a high risk of acute rejection and allograft loss. This study aimed to investigate…
  • 2020 American Transplant Congress

    Clinical Study of Standard versus Reduced Dose Tacrolimus Combined with Generic Mycophenolate Mofetil in De Novo Kidney Transplantation

    J. Bang, C. Oh

    Department of Surgery, Ajou University Medical School, Suwon, Korea, Republic of

    *Purpose: The lowering of calcineurin inhibitor exposure is possibly considered as the proper strategy to prevent calcineurin inhibitor induced nephrotoxicity in kidney transplant. This clinical…
  • 2020 American Transplant Congress

    Morbidity in Lung Transplant for Connective Tissue Disease

    S. Minkove1, E. Bush2, P. Shah1

    1Pulmonary and Critical Care, Johns Hopkins, Baltimore, MD, 2Thoracic Surgery, Johns Hopkins, Baltimore, MD

    *Purpose: To evaluate the post-lung transplant comorbidities of patients with connective tissue disease (CTD) compared with an age-matched cohort of patients transplanted for idiopathic pulmonary…
  • 2020 American Transplant Congress

    De Novo Dosing of LCP-Tacrolimus Using Conservative Weight-Based Strategy Resulted in Supratherapeutic Trough Levels in Majority of Patients

    J. Dann, J. Geyston, M. Wassimi, K. Brayman, A. Doyle

    University of Virginia Health System, Charlottesville, VA

    *Purpose: Due to ongoing national drug shortages, our center transitioned to de novo use of LCP-tacrolimus (LCPT) in kidney transplant patients using a conservative dosing…
  • 2020 American Transplant Congress

    Evaluation of Pretransplant Serologies and Vaccination Rates in Kidney Transplant Candidates

    S. Schneider, C. Truax, A. Carlson, B. Clark, B. Sirandas, L. Smith

    Department of Pharmacy Services, University of Utah Health, Salt Lake City, UT

    *Purpose: Assessing serologic status presents opportunities to provide live vaccinations to solid organ transplant (SOT) candidates. This is especially important given the increased risk of…
  • 2020 American Transplant Congress

    B Cell Depletion with Anti-CD20 mAb Exacerbates Anti-Donor CD4+ T Cell Responses in Highly Sensitized Transplant Model

    A. Tanaka, K. Ide, Y. Tanaka, M. Ohira, H. Tahara, H. Morimoto, H. Ohdan

    Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan

    *Purpose: Preformed donor-specific anti-human leukocyte antigen antibodies (DSAs) have been associated with detrimental effects in transplant recipients. To eliminate preformed DSAs, we desensitized DSA-positive recipients…
  • 2020 American Transplant Congress

    Antibiotic Stewardship and Inpatient C. Difficile Testing in Solid Organ Transplant Recipients, the Value of Multi-Level Checks and Balances

    M. Kueht, R. Britt, R. Ferren, M. Mujtaba, R. Ramirez, R. Kulkarni, A. Lea, J. Fair, D. Reynoso

    University of Texas Medical Branch, Galveston, TX

    *Purpose: Diarrhea in the solid organ transplant recipient is a commonly encountered problem and is often multifactorial in etiology. Due to the combination of peri-operative…
  • 2020 American Transplant Congress

    Trough Level Compliance in Immunosuppression is Important to Protect Renal Function after Liver Transplantation – An Additional Analysis from the Hephaistos Study

    P. Schemmer1, F. Braun1, H. J. Schlitt1, A. Pascher1, C. G. Klein1, U. Neumann1, I. Kroeger2, P. Wimmer2, B. Nashan1

    1Hephaistos, Study Group, Germany, 2Novartis Pharma GmbH, Nürnberg, Germany

    *Purpose: Most immunosuppressive drugs are dosed according to trough levels (C0-levels). To achieve the optimal balance between efficacy and safety, it is important to avoid…
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