2020 American Transplant Congress
Sparing the Nephron in Liver Transplant Recipients with Antithymocyte Bridging: A Four Year Experience
*Purpose: Renal function decline after liver transplant (LT) remains a significant issue. Using antithymocyte globulin (rATG) to delay tacrolimus (TAC) initiation may impact renal deterioration;…2020 American Transplant Congress
Depletional Profiles of Human and Rhesus Specific Anti-Thymocyte Globulins in Rhesus Macaques
*Purpose: Rabbit anti-human ATG (rATG; Thymoglobulin®) is the most commonly used formulation for depletional induction therapy in the United States. However, given that it is…2020 American Transplant Congress
Adenovirus Infection in Pediatric Liver Transplant Recipients: A Single Center Experience
*Purpose: Immunosuppression predisposes children to primary viral or latent infections after liver transplantation (LT). The impact of adenovirus infections on morbidity and mortality remains largely…2020 American Transplant Congress
Laminin Alpha5 Regulates T Cell Entry and Distribution in Lymph Nodes in Immunity
1UMB, Baltimore, MD, 2Harvard University, Boston, MA
*Purpose: Laminin α5 (Lama5) and α4 (Lama4) are lymph node (LN) stromal fibers whose expression ratio influences CD4+ T cell migration and stimulation. We hypothesized…2020 American Transplant Congress
Development of DSA Class II is Associated with Immunosuppressive Monotherapy and Increased Risk for Graft Fibrosis, Chronic Rejection and Graft Loss
*Purpose: Recent studies have suggested a negative impact of class 2 DSA on short term outcome of OLT recipients. The aim of this study was…2020 American Transplant Congress
Targeted Urine Metabolomics for Monitoring Renal Allograft Injury and Immunosuppression
University of California San Francisco, San Francisco, CA
*Purpose: The purpose of this study was to apply high-throughput metabolomics and machine learning to identify surrogate urine metabolite biomarkers for acute rejection vs. BK…2020 American Transplant Congress
Plasma Microbiome Profiles of Liver Transplant Patients with Operational Tolerance
*Purpose: Microbiome has emerged as a key modulator of organ homeostasis and immune system function with altered microbiota and microbiome - host interactions contributing to…2020 American Transplant Congress
The Use of Cell-Free MicroRNAs for the Diagnosis of Allograft Rejection in Liver Transplant Recipients Using Standard and Novel Direct Detection Platforms
*Purpose: Standard immunosuppression therapy (IST) in liver transplant (LTx) recipients requires a delicate balance to prevent side effects and allograft rejection (AR). There is no…2020 American Transplant Congress
Graft versus Host Disease in Liver Transplant Recipients: A Case Series
Cleveland Clinic Florida, Weston, FL
*Purpose: Graft Versus Host Disease (GvHD) is a serious and potentially fatal disease that is rarely observed in solid organ transplant recipients; however, we report…2020 American Transplant Congress
Medication Non-Adherence (MNA) Mitigation Practices and Health Care Professional (HCP) Perceptions at U.S. Transplant Centers
*Purpose: Extensive literature exists on risk factors and mitigating strategies for MNA, however information on MNA management within U.S. transplant centers is scarce. This survey…
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