ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2015 American Transplant Congress

    Interference of Therapeutic Antibodies Used in Desensitization Protocols On Lymphocytotoxicity Crossmatch Results

    D. Milongo,1,3 G. Vieu,2,4,3 S. Blavy,2,4 A. Del Bello,1,3 F. Sallusto,5 L. Rostaing,1,3 N. Kamar,1,3 N. Congy-Jolivet.2,4,3

    1Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France; 2Laboratoire d'Immunologie, CHU de Toulouse, Toulouse, France; 3Université Toulouse III Paul-Sabatier, Toulouse, France; 4Laboratoire d'Immunogénétique Moléculaire, EA 3034, Université Toulouse III Paul-Sabatier, Toulouse, France; 5Department of Urology, CHU Rangueil, Toulouse, France.

    Background: Therapeutic antibodies used to desensitize patients awaiting a human leukocyte antigen (HLA) or ABO-mismatched graft are suspected to interfere with the lymphocytotoxicity crossmatch (LCT-XM)…
  • 2015 American Transplant Congress

    CMV prevalence in Mauritian and Indonesian Cynomolgus Macaques: Significance in Transplantation and CMV Disease Models

    K. Premanand,1 E. Szilagyi,1 J. Yu,1 R. Patel,1 A. Antony,1 M. Willman,2 D. Berman-Weinberg,2 D. Han,2 A. Vaidya,3 E. Silva,3 K. McHenry,3 D. Salomon,4 N. Kenyon,2 A. Bartholomew.1

    1University of Illinois, Chicago; 2Univerisity of Miami, Miami; 3University of Illinois, Urbana; 4Scripps, San Diego.

    Despite the finding that most macaques express high serologic titers of anti-CMV antibody, susceptibility to disease appears to be variable post-transplant. This observation led us…
  • 2015 American Transplant Congress

    Steroid-Free Quadruple Induction Regimen With Basiliximab, Everolimus, Mycophenolate and Very Low Dose Tacrolimus Reduces Incidence of Biopsy-Proven Acute Rejection and Toxicity Profile Compared to the Standard Triple Regimen

    M. Miura, H. Higashiyama.

    Department of Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.

    Objectives: Nephrotoxicity of calcineurin inhibitors (CNI) in kidney allografts has been a significant clinical problem even with low exposure regimens. On the other hand, CNI-free…
  • 2015 American Transplant Congress

    Safety and Efficacy of Low Dose and Very Low Dose Extended-Release Tacrolimus / MMF in De Novo Kidney Transplant Recipients

    Y. Watarai,1 M. Okada,1 K. Futamura,1 K. Ito,1 T. Yamamoto,1 M. Tsujita,1 T. Hiramitsu,1 N. Goto,1 S. Narumi,1 T. Kobayashi.2

    1Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan; 2Applied Immunology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

    Recently, once-daily tacrolimus extended-release formulation (TACER) has been accepted in kidney transplantation, however its optimal dosing are not well evaluated. We have validated low dose…
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