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American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2016 American Transplant Congress

    The Impact of Different Immunosuppressive Protocols on Early and Long Term Outcomes After Kidney and Pancreas Transplantation.

    A. Rajab, R. Pelletier, A. El-Hinnawi, E. Elkhammas, G. Bumgardner, M. Henry.

    Surgery/Transplant, The Ohio State University Wexner Medical Center, Columbus, OH.

    Between January 1990 and December 2014, 800 combined kidney pancreas transplant procedures were performed at The Ohio State University. The immunosuppressive protocols have changed significantly…
  • 2016 American Transplant Congress

    Appraisal of Alternative Immunosuppression Regimens in Intestinal Transplant Recipients: A Single Center Experience.

    R. Patel, M. Keck, D. Collier, M. Vacha.

    Nebraska Medicine, Omaha, NE.

    Purpose: The purpose of this study was to compare outcomes (acute cellular rejection, graft loss, mortality) in intestinal transplant recipients who were converted from the…
  • 2016 American Transplant Congress

    High Tacrolimus Dose Requirements at Month 6 Are Associated with Inferior Graft Function in Renal Transplant Patients.

    O. Rissling, S. Brakemeier, L. Lehner, F. Halleck, O. Staeck, D. Schmidt, K. Budde.

    Department of Nephrology, Charité Universitaetsmedizin, Berlin, Germany.

    Introduction: Tacrolimus (Tac), the mainstay of immunosuppression in renal transplant (tx) patients (pts) is known for drug induced nephrotoxicity, which may limit graft survival.Methods: In…
  • 2016 American Transplant Congress

    Steroid Use May Not Increase Risk of Fracture in Kidney Transplant Patients.

    N. Sarabu, K. Kucharski, D. Hricik, A. Padiyar, A. Huml, J. Augustine.

    Internal Medicine, Division of Nephrology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH.

    Introduction: Chronic steroid use is associated with bone mineral loss, and osteoporosis. However, it is not clear if chronic steroid use in post-kidney transplant patients…
  • 2016 American Transplant Congress

    Tumor-Necrosis-Factor-α Antagonist Therapy for Inflammatory Bowel Disease After Liver Transplantation.

    R. Parekh, M. Segovia, N. Kaur.

    Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI.

    Background:The safety and effectiveness of tumor-necrosis-factor-α antagonist (anti-TNF-α) therapy for inflammatory bowel disease (IBD) has not been well-established in patients after liver transplantation (LT). We…
  • 2016 American Transplant Congress

    Excellent Results of Living-Related Renal Transplant Recipients Treated with High-Dose Mizoribine – Comparison of Taclorimus with CsA for Two Years Result by a Japanese Multicenter Study.

    N. Yoshimura, K. Nishimura, K. Akioka, M. Shimazu, K. Nose, T. Nishioka, N. Nakamura, K. Uchida, T. Nakatani, H. Ushigome.

    Japanese Multicenter Study Group of High Dose Mizoribine in Kidney Transplantation, Kyoto, Japan.

    (Aims) Mizoribine (MZR) has been developed as an immunosuppressive agent, but has a less potent immunosuppressive effect up to 3 mg/kg/day. The widespread use of…
  • 2016 American Transplant Congress

    Long-Term Outcomes in Pediatric Live-Donor Liver Transplantation.

    N. Celik,1 A. Ganoza,2 F. Vyas,1 J. Squires,3 V. Venkat,3 G. Bond,1 K. Soltys,1 R. Sindhi,1 R. Squires,3 A. Humar,2 G. Mazariegos.1

    1Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Thomas E. Starzl Transplantation Institute, Department of Surgery at UPMC, Pittsburgh, PA; 3Division of Pediatric Gastroenterology, CHP of UPMC, Pittsburgh, PA.

    Aim: To determine the incidence of allograft and medical factors characterizing optimal patient outcomes 3 year or more after pediatric live-donor liver transplantation (LDLT). Methods:…
  • 2016 American Transplant Congress

    Targeting the Constitutively Active PI3K/Akt/mTOR Signaling Pathway in Epstein-Barr Virus B Cell Lymphomas.

    A. Sang, G. Ivison, C. Esquivel, S. Krams, O. Martinez.

    Division of Abdominal Transplantation, Stanford School of Medicine, Stanford, CA.

    Epstein-Barr virus (EBV) B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD) is a major problem in organ transplantation. Reduction of immunosuppression sometimes result in tumor…
  • 2016 American Transplant Congress

    Rapamycin Encapsulated Nanoparticles as Pre-Treatment in Lung Transplantation.

    G. Bazzle,1 S. Dixit,2 K. Patel,3 A.-M. Broome,2 S. Nadig,1,3 C. Atkinson.1,3

    1Microbiology and Immunology, Medical University of South Carolina, Charleston, SC; 2Department of Radiology, Medical University of South Carolina, Charleston, SC; 3Department of Surgery, Medical University of South Carolina, Charleston, SC.

    Introduction: While short-term lung transplant outcomes have improved over the years, long-term survival rates remain stagnant. Many injuries occur to the donor organ before transplantation,…
  • 2016 American Transplant Congress

    Earlier Repletion of Lymphocytes After Alemtuzumab Induction Is Associated with a Lower Incidence of Infection Following Renal Transplantation.

    M. Willicombe, D. Goodall, A. McLean, D. Taube.

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Introduction: Alemtuzumab has been increasingly used as an induction agent in renal transplantation, although the optimal dose is unknown. We have previously reported that alemtuzumab…
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