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American Transplant Congress abstracts

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Articles tagged "Hypersensitivity"

  • 2021 American Transplant Congress

    Kidney Transplant Associated Allergy Transfer After Living Donation

    K. López-Vega, S. Davis

    Division of Renal Diseases and Hypertension, Anschutz Medical Campus, University of Colorado, Aurora, CO

    *Purpose: Donor to recipient IgE-mediated food allergy transfer has been described in non-kidney solid organ transplant. Here, we report a novel case of an adult…
  • 2019 American Transplant Congress

    Use of mTOR Inhibitors in Hypersensitized Kidney Transplant Recipients: Breaking False Myths

    D. Cucchiari1, A. Molina-Andujar1, E. Montagud-Marrahi1, F. J. Centellas-Pérez2, I. Revuelta1, F. Oppenheimer1, F. Diekmann1

    1Renal Transplant Unit, Hospital Clínic, Barcelona, Spain, 2Complejo Hospitalario Universitario, Albacete, Spain

    *Purpose: Many centers avoid the use of mTOR inhibitors (mTORi) in hypersensitized kidney transplant recipients and usually employ an immunosuppression based on Mycophenolic Acid (MPA),…
  • 2018 American Transplant Congress

    Glycolytic Bias in mTORC2-Deficient Dendritic Cells Potentiates Antigen-Specific Immunity and Accelerates Graft Rejection

    A. Watson,1 H. Dai,1 J. Diaz-Perez,2 A. Menk,3 M. Killeen,2 G. Delgoffe,3 A. Mathers,2 A. Thomson.1

    1Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; 2Dermatology, University of Pittsburgh, Pittsburgh, PA; 3Cancer Institute, University of Pittsburgh, Pittsburgh, PA.

    The mechanistic target of rapamycin (mTOR) is known to function in two complexes: mTOR complex 1 (mTORC1) and mTORC2. While the function of mTORC1 in…
  • 2018 American Transplant Congress

    Targeting LTβR Classical NFκB Signaling Facilitates Inflammation Resolution

    W. Piao, Y. Xiong, L. Li, V. Saxena, J. Bromberg.

    UMB, Baltimore.

    Background:Contact hypersensitivity (CHS) is a reliable model to assess the immune cell-mediated cutaneous inflammatory response, which includes the three phases of priming/sensitization, elicitation, and resolution,…

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