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Articles tagged "Hyperglycemia"

  • 2015 American Transplant Congress

    Human iPS Cell-Derived Pancreatic β-Cells Correct Hyperglycemia in Diabetic Mice

    G. Manzar,1,2,3 E.-M. Kim,1,2 P. Rotti,3 N. Zavazava.1,2,3

    1Internal Medicine, University of Iowa, Iowa City, IA; 2VA Medical Center, Iowa City, IA; 3Biomedical Engineering, University of Iowa, Iowa City, IA.

    Type I diabetes (T1D) is an autoimmune disorder that leads to the destruction of pancreatic β-cells. The consequences of T1D are dysregulation of metabolism leading…
  • 2015 American Transplant Congress

    Pancreatic Islet Survival Under Confinement

    A. Rodriguez, S. Sigrist, E. Maillard.

    UMR DIATHEC EA 7294, Centre Européen d'Etude du Diabète, Strasbourg, France.

    The main advantage of cell therapy is the possibility to immune-isolate the graft in a device to avoid immune suppressive regimen. In islet transplantation field,…
  • 2015 American Transplant Congress

    The Use of a Nurse Practitioner Led Transitional Diabetes Clinic Following Transplantation

    N. Cardinez, P. Segal, S. Trohonel.

    Endocrinology Department, University Health Network - Toronto General Hospital, Toronto, ON, Canada.

    The incidence of new onset diabetes after transplant [NODAT] ranges from 2% to 53%, also Type1 [T1DM] and Type 2 [T2DM] diabetes are common in…
  • 2015 American Transplant Congress

    Diabetes Exacerbates Liver Ischemia and Reperfusion Injury By Activating the AGE-RAGE Pathway in Kupffer Cells

    S. Yue, J. Zhu, J. Rao, J. Kupiec-Weglinski, R. Busuttil, Y. Zhai.

    Surgery, UCLA, Los Angeles, CA.

    Although pre-transplant diabetes has been documented as a risk factor for mortality post-liver transplant, the underlying mechanism remains obscure. In a murine liver partial warm…
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