ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Hyperglycemia"

  • 2019 American Transplant Congress

    FK506 Influence Glucose Metabolism by Short Chain Fatty Acid

    W. Jiao1, Z. Zhang1, L. Liu2, X. Hu1

    1Urology, Capital Medical University Beijing Chaoyang Hospital, Beijing, China, 2GI Divison, West China Hospital, Beijing, China

    *Purpose: FK506 is one of the most common immunosuppressant drugs in organ transplantation, which have been demonstrated to cause glucose metabolism disorder and alterd the…
  • 2019 American Transplant Congress

    Belatacept Based Simultaneous Calcineurin Inhibitor Avoidance/Early Corticosteroid Withdrawal is Associated with Low New Onset Diabetes Risk

    A. R. Shields1, P. West-Thielke2, E. S. Woodle1, D. B. Kaufman3, J. Lipscomb4, J. P. Leone5, A. Wiseman6, E. King4, A. J. Matas7, R. R. Alloway for the BEST Study Group4

    1Transplant Surgery, U of Cincinnati, Cincinnati, OH, 2UIC, Chicago, IL, 3Transplant Surgery, U of Wisconsin, Madison, WI, 4U of Cincinnati, Cincinnati, OH, 5Tampa General, Tampa, FL, 6U of Colorado, Denver, CO, 7U Minnesota, Minneapolis, MN

    *Purpose: Calcineurin inhibitor (CNI) and/or corticosteroid (CCS) therapy are associated with significant risk of new onset diabetes after transplantation (NODAT). An important consideration for simultaneous…
  • 2019 American Transplant Congress

    The Impact of Sleeve Gastrectomy Following Liver Transplant in Patients with Non-Alcoholic Steatosis: A Five-Year Experience

    M. C. Morris1, A. D. Jung1, Y. Kim1, V. K. Dhar1, S. Shah1, D. Schauer2, E. Smith2, T. Diwan1

    1Surgery, University of Cincinnati, Cincinnati, OH, 2Medicine, University of Cincinnati, Cincinnati, OH

    *Purpose: Non-alcoholic steatohepatitis (NASH) cirrhosis is an increasingly common indication for liver transplantation (LT) in the United States and obese patients continue to be at…
  • 2019 American Transplant Congress

    Blood Group Incompatible Living Donor Kidney Transplantation in Patients with End-Stage Kidney Disease Due to Diabetes Kidney Disease

    J. Uchida1, A. Kosoku1, K. Kabei1, S. Nishide1, H. Shimada1, K. Maeda2, Y. Yoshikawa3, T. Iwai1, N. Kuwabara1, T. Naganuma1, N. Kumada4, Y. Takemoto1, T. Nakatani1

    1Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, 2Nursing, Osaka City University Hospital, Osaka, Japan, 3Osaka City University, Osaka, Japan, 4Urology, Suita Municipal Hospital, Suita, Japan

    *Purpose: Diabetes is a growing public health problem, and diabetes kidney disease (DKD) is the most prevalent chronic kidney disease and the major cause of…
  • 2019 American Transplant Congress

    HbA1c as a Noninvasive Predictor of Chronic Histopathologic Changes in Living Donors for Kidney Transplantation

    K. Tanaka1, S. Nishida1, K. Kinoshita1, Y. Hidaka1, M. Toyoda2, A. Inadome3, A. Takeda4, H. Yokomizo5, S. Uekihara6, J. Shoji7, S. Yamanaga1

    1Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, 2general medicine, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, 3Urology, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, 4Nephrology, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Japan, 5Surgery, Japanese Red Cross Kumamoto Hospital, kumamoto, Japan, 6general medicine, Japanese Red Cross Kumamoto Hospital, kumamoto, Japan, 7Nephrology, UCSF Connie Frank Transplant Center, San francisco, CA

    *Purpose: The degree of chronic histopathologic changes in renal allografts, including interstitial fibrosis, tubular atrophy, and arteriolar hyalinosis, can have clinical implications in long-term allograft…
  • 2019 American Transplant Congress

    Impact of Hepatitis C Viremia on Post-Transplant Diabetes Mellitus Development in Liver Transplant Recipients

    K. Klein1, J. Nelson2, B. Crowther1, C. Guerra3, E. Kincaide1, K. V. Speeg4, N. Alkhouri5, R. Hall1

    1University Health System, The University of Texas at Austin, College of Pharmacy, Pharmacotherapy Division, Austin, TX, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 2University Health System, San Antonio, TX, 3The University of Texas Health Science Center at San Antonio, University of the Incarnate Word Feik School of Pharmacy, San Antonio, TX, 4University Health System, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 5University Health System, The University of Texas Health Science Center at San Antonio, Texas Liver Institute, San Antonio, TX

    *Purpose: Compare incidence of post-transplant diabetes mellitus (PTDM) in hepatitis C virus (HCV) patients with and without viremia at the time of orthotopic liver transplantation…
  • 2019 American Transplant Congress

    Hyperglycemia Aggravates Acute Liver Injury by Promoting Macrophage NLRP3 Activation via AMPK/mTOR-Dependent Autophagy Inhibition

    H. ZHOU, Q. Wang, R. Liu, S. Zhou, F. Cheng, X. Wang, L. Lu

    The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    *Purpose: The detrimental effects of diabetes mellitus/hyperglycemia include an increase in the oxidative stress response and an enhanced inflammatory response. Despite an increased understanding of…
  • 2019 American Transplant Congress

    Inpatient versus Outpatient Management of Hyperglycemia in Post-Transplant Patients Following High Dose Steroid Pulses for Acute Rejection

    J. L. Wisniewski1, W. Bruneau2, E. A. Cohen2

    1University of Connecticut, School of Pharmacy, Storrs, CT, 2Yale New Haven Hospital, New Haven, CT

    *Purpose: Acute cellular rejection (ACR) occurs in approximately ten percent of all transplant patients and is typically treated with multiple infusions of high-dose steroids (HDS).…
  • 2018 American Transplant Congress

    Hyperglycemia Aggravates Hepatic Ischemia and Reperfusion Injury by Inhibiting Liver Resident Macrophage M2 Polarization via C/EBP-Homologous Protein-Mediated Endoplasmic Reticulum Stress

    Z. Rao, J. Sun, X. Pan, Z. Chen, H. Sun, P. Zhang, M. Gao, Z. Ding, C. Liu.

    Anesthesiology, First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

    Background:Aggravated liver ischemia and reperfusion (IR) injury has been observed in hyperglycemic hosts, but its underlying mechanism remains undefined. The aim of the study was…
  • 2018 American Transplant Congress

    The Price of Diabetes Medication Management in Kidney Transplantation: Similar Rates of Readmissions, but More Healthcare Utilization

    J. Hardcopf, H. Meadows, N. Pilch, C. Perez, N. Patel, J. Fleming, H. Corbo, T. Harrison, B. O'Brien, D. DuBay, D. Taber.

    Medical University of South Carolina, Charleston, SC.

    Background: The aim of this study was to determine whether changing diabetes (DM) medications during the index admission for kidney transplant (KT) is significantly associated…
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