2022 American Transplant Congress
Development of a Dynamic Map of Peripheral Myeloid Cells Associated with Acute Rejection of Vascularized Composite Tissue Allografts
*Purpose: Myeloid cells are involved in early alloactivation in response to organ allografts and can initiate acute rejection. The heterogeneity of myeloid populations and the…2020 American Transplant Congress
The Use of Allosure Donor Derived Cell-Free DNA in a Community Based Kidney Transplant Program
Kidney Transplantation, Christiana Care Hospital, Newark, DE
*Purpose: Donor derived cell-free DNA (dd-cfDNA) has emerged as a marker of kidney allograft injury. Beginning in 2019, the dd-cfDNA monitoring has been introduced as…2019 American Transplant Congress
Chimeric Allografts Induced by Stem Cell Mobilizing Agents in a Mouse Model of Kidney Transplantation: Role of CD133 Stem Cells
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: It has been reported that a stem cell mobilizing therapy using a combination of AMD3100 and low dose FK506 (AF) enabled immunosuppressive-free long-term kidney…2017 American Transplant Congress
Host-Derived, Intragraft Dendritic Cells Are Extensively Cross-Dressed by Donor MHC.
Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsbugh, PA
Host dendritic cells (DC) are the primary driver of transplant rejection in secondary lymphoid tissues where they activate alloreactive T cells. Directly alloreactive T cells…