2019 American Transplant Congress
Influence Of HLA-DR Mismatches On Long Term Outcomes Following Heart Transplantation
Division of Cardiology/ JC Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, TX
*Purpose: In the field of kidney transplantation, there is strong support for the beneficial effect of minimizing donor-recipient HLA incompatibility, and HLA-DR matching in particular…2019 American Transplant Congress
Effect of HLA Mismatch on Recurrence and Graft Loss in Living versus Deceased Kidney Transplant Recipients with IgA Nephropathy
Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: A registry based study from Australia and New Zealand reported increased risk of recurrent IgA nephropathy (IgAN) in zero-HLA-mismatched living donor kidney transplant (LDKT)…2018 American Transplant Congress
Epitope/Eplet Mismatch in Pediatric Renal Transplantation and Development of Donor Specific Antibody
Background: De-novo donor specific antibody (DSA) is one of the strongest independent predictors of graft loss with HLA mismatching being a major risk factor for…2018 American Transplant Congress
Feasibility of a National Class II Matching Strategy for Pediatric Kidney Transplant Candidates
Antibody-mediated rejection (AMR) is a major concern for allograft failure, which could be mitigated by allocation of Class II matched donors. Since children have priority,…2018 American Transplant Congress
High Frequency of HLA-DQ De Novo Donor Specific Antibodies is Independent of the Number of Mismatches in Heart Transplant
Aim: Development of de novo donor specific antibodies (DSA) after heart transplant is associated with an increased risk of allograft failure. The aim of this…2018 American Transplant Congress
Shared HLA Specificities between the Blood and Transplant Donor Increases the Risk of De Novo DSA Development Following Blood Transfusion in Transplant Recipients
Introduction: Blood transfusions post-transplant have been shown to be associated with the development of de novo DSA and inferior allograft outcomes. The mechanisms behind this…2018 American Transplant Congress
HLA Eplet Mismatch and Donor Specific Antibodies in Kidney Transplantation
BACKGROUND: Although HLA matching improves graft survival in kidney transplant recipients (KTx), eplet mismatches provide higher resolution information, and could better predict the development of…2018 American Transplant Congress
The Results of Plasmapheresis and Anti-CD20 Based Desensitization without Intravenous Immunoglobulin in Positive Crossmatch Kidney Transplants
Asan Medical Center, Seoul, Korea.
This study examined the mid-term clinical outcomes in positive crossmatch kidney transplants (XMKT) for patients who received desensitization with plasmapheresis (PP) and anti-CD20 based regimens…2018 American Transplant Congress
Temporal Changes in Impact of HLA Mismatch among Pediatric Kidney Transplant Recipients
Johns Hopkins University School of Medicine, Baltimore, MD.
U.S. pediatric deceased-donor kidney transplantation (pDDKT) allocation now deemphasizes HLA matching to improve equality in access to transplantation, but other national systems still consider HLA…2018 American Transplant Congress
ABO Incompatible Deceased Donor Kidney Transplantation – Time to Remove the Barrier
Objective: To propose a new allocation system for deceased donor kidney transplants that would decrease cold ischemia time, increase HLA matching, decrease kidney discard rates…
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