2018 American Transplant Congress
Impact of De Novo DSA Development and Management on Kidney Transplant Outcomes
Multiple studies have shown that development of donor specific antibodies (DSAs) can have a negative impact on renal allograft outcomes resulting in decreased renal function,…2018 American Transplant Congress
Outcomes of Organ Transplantation from Donors with Cancer History
Purpose: The inherent challenges of selecting an acceptable donor for each of the increasing numbers and acuity of recipients has led programs to take increased…2018 American Transplant Congress
Using the Remuzzi Score to Guide Single vs. Dual Transplantation Mitigates the Risk of Early Graft Failure
Surgery, University of Cambridge, Cambridge, United Kingdom.
BackgroundExpanded criteria circulatory death donors (DCD) may represent an underutilised donor pool. Our centre has used urgent pre-implantation biopsy (Remuzzi score) to guide single (SKT)…2018 American Transplant Congress
Early versus Late Cytomegalovirus Prophylaxis after Kidney Transplant
Duke University Hospital, Durham, NC.
Background: Prophylaxis against cytomegalovirus (CMV) is recommended in high-risk patients (CMV D+/R-) and those who are CMVR+ and getting T-cell depletional therapy. It is unclear…2018 American Transplant Congress
Economic Evaluation of Contemporary Kidney Transplant Practice
Kidney transplantation (KTx) has been established as the optimal therapy for medically suitable patients with end-stage renal disease, prolonging survival and reducing health care spending.…2018 American Transplant Congress
Reducing Discards for Deceased Kidney Donors over Age 50 by Restricting Biopsy Criteria
Clinical Division, Gift of Life Michigan, Ann Arbor, MI.
The placement of kidneys from deceased organ donors of advanced age is an ongoing challenge. An Organ Procurement Organization (OPO) evaluated its discard rate for…2018 American Transplant Congress
Major Adverse Cardiovascular Events Following Simultaneous Pancreas and Kidney Transplantation. A Study of the United Kingdom Transplant Registry
BackgroundPatients with type 1 diabetes mellitus (T1DM) and end-stage renal disease (ESRD) suffer increased cardiovascular morbidity and mortality. Simultaneous pancreas and kidney transplantation (SPKT) improves…2018 American Transplant Congress
Val-Ganciclovir Prophylaxis Delays Onset of EBV Viremia in the First Year Post-Solid Organ Transplantation in High-Risk Patients
1University of British Columbia, Vancouver, Canada; 2University of Manitoba, Winnipeg, Canada.
Introduction: Donor-derived primary Epstein-Barr virus (EBV) infection poses serious risks to EBV naïve children post-solid organ transplantation, including development of EBV-related PTLD. Currently, there is…2018 American Transplant Congress
Clinical Response to Salvage Bortezomib Therapy for Antibody Mediated Rejection and Mixed Acute Rejection in a High Immunologic Risk Renal Transplant Population
University of Illinois at Chicago, Chicago, IL.
Background: Proteasome inhibitor (PI) containing regimens treat antibody mediated rejection (AMR) and mixed acute rejection (MAR) due to elimination of donor specific antibody (DSA). Commonly,…2017 American Transplant Congress
The Use of a Furosemide Stress Test (FST) for Assessment of Discarded Deceased Donor Kidneys in an Ex-Vivo Normothermic Perfusion Model.
Department of Surgery, UC Davis Medical Center, Sacramento, CA
Studies have shown that Ex-Vivo Normothermic Perfusion (EVNP) has the potential to assess viability and function of high-risk deceased donor kidneys. A diuretic response to…
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