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American Transplant Congress abstracts

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Articles tagged "Hepatocellular carcinoma"

  • 2015 American Transplant Congress

    Predictors of Time to Recurrence and Mortality Associated With Recurrent Hepatocellular Carcinoma After Liver Transplantation

    A. Bodzin, D. Reino, K. Lunsford, M. Harlander-Locke, D. Markovich, A. Zarrinpar, F. Kaldas, D. Farmer, R. Busuttil, V. Agopian.

    Transplantation, UCLA, Los Angeles, CA.

    Background: While recurrent hepatocellular carcinoma (HCC) after liver transplantation (LT) portends a poor prognosis, adjuvant therapy may prolong survival. We sought to identify factors that…
  • 2015 American Transplant Congress

    Clinical Impact of 18F-FDG-PET/CT in Living Donor Liver Transplantation for Advanced Hepatocellular Carcinoma

    S. Lee, S. Kim.

    Liver Cancer Center, National Cancer Center, Goyang, Korea.

    Background: The relevant number of patients with hepatocellular carcinoma (HCC) beyond the Milan criteria has undergone living donor liver transplantation (LDLT). However, the prognostic factors…
  • 2015 American Transplant Congress

    Adoptive Immunotherapy With Liver Allograft-Derived NK Cells Improves Recurrence-Free Survival After Living-Donor Liver Transplantation in Patients With Hepatocellular Carcinoma

    N. Tanimine, Y. Tanaka, K. Ishiyama, M. Ohira, S. Shimizu, T. Yano, H. Ohdan.

    Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    Introduction: Previous studies revealed that the recurrence rate of hepatocellular carcinoma (HCC) was still 10–20%, even among liver transplantation (LT) recipients meeting the Milan criteria…
  • 2015 American Transplant Congress

    Liver Transplantation for Hepatocellular Carcinoma inside Milan Criteria: Lower Recurrence in Patients With Hepatitis C Infection

    W. Palmer, D. Lee, J. Burns, A. Keaveny, J. Melendez, J. Nguyen, T. Patel, S. Pungpapong, B. Rosser, R. Paz-Fumagalli, R. Nakhleh, K. Musto, D. Harnois.

    Mayo Clinic, Jacksonville, FL.

    Purpose: Hepatitis C infection (HCV) related-cirrhosis can lead to hepatocellular carcinoma (HCC). Liver transplantation (LT) is the optimal treatment for selected patients with HCC, providing…
  • 2015 American Transplant Congress

    Split and Living Donor Versus Whole Liver Transplantation for Hepatocellular Carcinoma in Adult Recipients: A Single Center Analysis

    O. Boillot, O. Guillaud, J. Dumortier.

    Liver Transplant Unit, Edouard Herriot Hospital, lyon, France.

    INTRODUCTIONThe use of partial liver grafts in the context of hepatocellular carcinoma (HCC) remains a matter ofdebate because of a supposed higher risk of cancer…
  • 2015 American Transplant Congress

    Association Between Polymorphisms of PPM1E Gene and Tumor Size of Hepatocellular Carcinoma Patients

    M.-S. Park,1 S.-K. Kim.2

    1Surgery, Kyung Hee University Hospital, Seoul, Korea; 2Pharmacology, Kyung Hee University, Seoul, Korea.

    The protein phosphatase, Mg2+/Mn2+ dependent, 1E (PPM1E) inactivates multiple substrates including 5'-AMP activate protein kinases (AMPK) which inhibits the growth and survival of cancer cells.…
  • 2015 American Transplant Congress

    Grip Strength, Gait Speed, and Chair Stands Predict Sarcopenia in Male But Not Female Liver Transplant Candidates

    C. Wang, S. Feng, K. Covinsky, H. Hayssen, B. Yeh, J. Lai.

    University of California, San Francisco, San Francisco, CA.

    Background: Sarcopenia, as determined by cross-sectional skeletal muscle index (SMI), is associated with waitlist mortality in liver transplant (LT) candidates, but has limited clinical utility…
  • 2015 American Transplant Congress

    Recurrence of Hepatocellular Carcinoma After Transarterial Chemoembolization (TACE) Alone and TACE in Combination With Other Treatment Modalities

    J. Balogh, A. Islam, A. Saharia, H. Monsour, S. Gordon Burroughs, M. Weiner, A. Gaber, R. Ghobrial.

    General Surgery, Houston Methodist Hospital, Houston, TX.

    AIM:Treatment of hepatocellular carcinoma (HCC) with transarterial chemoembolization (TACE) can help downstage tumors prior to orthotopic liver transplantation (OLT); however, there is a risk of…
  • 2015 American Transplant Congress

    Early Detection of HCC Mutations in Indeterminate Lesions Using Liquid Biopsies

    Y. Lin,1 K. Cavaness,2 Z. Zhang,1 S. Lin,3 K. Korenblat,1 G. Klintmalm,2 W. Chapman.1

    1Washington University, St. Louis, MO; 2Baylor University, Dallas, TX; 3Stanford University, Palo Alto, CA.

    Background Recent sequencing efforts have characterized the mutation profile of hepatocellular carcinoma (HCC); however, the relevance to clinical decision-making has been limited by the infrequency…
  • 2015 American Transplant Congress

    Long-Term Outcome After Liver Transplantation for Unresectable Hepatocellular Carcinoma Following Yttrium-90 Radioembolization Bridging Treatment

    S. Radunz,1 T. Benkoe,1 J. Best,2 A. Bockisch,3 T. Lauenstein,4 H. Baba,5 A. Paul,1 J. Treckmann.1

    1General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany; 2Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany; 3Nuclear Medicine, University Hospital Essen, Essen, Germany; 4Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany; 5Pathology and Neuropathology, University Hospital Essen, Essen, Germany.

    Background: Liver transplantation remains the only curative treatment option for patients with unresectable hepatocellular carcinoma (HCC). Several bridging treatments are employed because the limited availability…
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