ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Hepatocellular carcinoma"

  • 2015 American Transplant Congress

    Split and Living Donor Versus Whole Liver Transplantation for Hepatocellular Carcinoma in Adult Recipients: A Single Center Analysis

    O. Boillot, O. Guillaud, J. Dumortier.

    Liver Transplant Unit, Edouard Herriot Hospital, lyon, France.

    INTRODUCTIONThe use of partial liver grafts in the context of hepatocellular carcinoma (HCC) remains a matter ofdebate because of a supposed higher risk of cancer…
  • 2015 American Transplant Congress

    Association Between Polymorphisms of PPM1E Gene and Tumor Size of Hepatocellular Carcinoma Patients

    M.-S. Park,1 S.-K. Kim.2

    1Surgery, Kyung Hee University Hospital, Seoul, Korea; 2Pharmacology, Kyung Hee University, Seoul, Korea.

    The protein phosphatase, Mg2+/Mn2+ dependent, 1E (PPM1E) inactivates multiple substrates including 5'-AMP activate protein kinases (AMPK) which inhibits the growth and survival of cancer cells.…
  • 2015 American Transplant Congress

    Grip Strength, Gait Speed, and Chair Stands Predict Sarcopenia in Male But Not Female Liver Transplant Candidates

    C. Wang, S. Feng, K. Covinsky, H. Hayssen, B. Yeh, J. Lai.

    University of California, San Francisco, San Francisco, CA.

    Background: Sarcopenia, as determined by cross-sectional skeletal muscle index (SMI), is associated with waitlist mortality in liver transplant (LT) candidates, but has limited clinical utility…
  • 2015 American Transplant Congress

    Recurrence of Hepatocellular Carcinoma After Transarterial Chemoembolization (TACE) Alone and TACE in Combination With Other Treatment Modalities

    J. Balogh, A. Islam, A. Saharia, H. Monsour, S. Gordon Burroughs, M. Weiner, A. Gaber, R. Ghobrial.

    General Surgery, Houston Methodist Hospital, Houston, TX.

    AIM:Treatment of hepatocellular carcinoma (HCC) with transarterial chemoembolization (TACE) can help downstage tumors prior to orthotopic liver transplantation (OLT); however, there is a risk of…
  • 2015 American Transplant Congress

    Early Detection of HCC Mutations in Indeterminate Lesions Using Liquid Biopsies

    Y. Lin,1 K. Cavaness,2 Z. Zhang,1 S. Lin,3 K. Korenblat,1 G. Klintmalm,2 W. Chapman.1

    1Washington University, St. Louis, MO; 2Baylor University, Dallas, TX; 3Stanford University, Palo Alto, CA.

    Background Recent sequencing efforts have characterized the mutation profile of hepatocellular carcinoma (HCC); however, the relevance to clinical decision-making has been limited by the infrequency…
  • 2015 American Transplant Congress

    Long-Term Outcome After Liver Transplantation for Unresectable Hepatocellular Carcinoma Following Yttrium-90 Radioembolization Bridging Treatment

    S. Radunz,1 T. Benkoe,1 J. Best,2 A. Bockisch,3 T. Lauenstein,4 H. Baba,5 A. Paul,1 J. Treckmann.1

    1General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany; 2Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany; 3Nuclear Medicine, University Hospital Essen, Essen, Germany; 4Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany; 5Pathology and Neuropathology, University Hospital Essen, Essen, Germany.

    Background: Liver transplantation remains the only curative treatment option for patients with unresectable hepatocellular carcinoma (HCC). Several bridging treatments are employed because the limited availability…
  • 2015 American Transplant Congress

    Listing for Liver Transplantation of Patients With Hepatocellular Carcinoma Using the Extended Toronto Criteria; an Intention-to-Treat Analysis

    G. Sapisochin, N. Goldaracena, J. Laurence, A. Barbas, M. Dib, A. Ghanekar, M. Selzner, L. Lilly, I. McGilvray, M. Cattral, E. Renner, P. Greig, D. Grant.

    Multi-Organ Transplant, Toronto General Hospital. University of Toronto, Toronto, ON, Canada.

    The role of liver transplantation for patients whose HCC exceeds Milan criteria remains controversial. At the University of Toronto, we have reported survivals of a…
  • 2015 American Transplant Congress

    Risk of Post Liver Transplant (LT) Hepatocellular Carcinoma (HCC) Recurrence Is 2-Fold Higher in Women Compared to Men With AFP Levels at LT Between 101-500

    M. Sarkar,1 J. Dodge,2 F. Yao,1 J. Roberts,2 N. Terrault,1 N. Mehta.1

    1Medicine, University of California, San Francisco, San Francisco; 2Surgery, University of California, San Francisco, San Francisco.

    Gender differences in HCC incidence are known, with men at greater risk than women. Pre transplant AFP levels strongly predict post LT HCC recurrence, though…
  • 2015 American Transplant Congress

    Alpha-Fetoprotein as a Modifier of Anatomic Criteria for Transplantation of HCC Patients

    A. Daoud,1,3 M. Ghobrial,1 L. Teeter,2 E. Graviss,2 E. Asham,1 S. Burroughs,1 A. Saharia,1 C. Mobley,1 S. Mogawer,3 A. Sholkamy,3 M. Elshazly,4 M. Boktour,1 A. Gaber.1

    1Transplant Center, Methodist Hospital, Houston, TX; 2Pathology and Genomic Medicine, Methodist Hospital, Houston, TX; 3Internal Medicine Department, Cairo University Medical school, Cairo, Egypt; 4Surgery Department, Cairo University Medical school, Cairo, Egypt.

    Background:The current listing criteria (Milan, UCSF) for Orthotropic Liver Transplants (OLT) in hepatocellular carcinoma (HCC) patients emphasize the anatomic features of the tumor such as…
  • 2015 American Transplant Congress

    The Negative Impact of Hepatitis C Infection (HCV+) On Orthotopic Liver Transplantation (OLT) for Hepatocellular Carcinoma (HCC)

    A. Daoud,1,3 L. Teeter,2 E. Graviss,2 S. Burroughs,1 A. Gaber.1

    1Transplant Center, Methodist Hospital, Houston, TX; 2Pathology and Genomic Medicine, Methodist Hospital, Houston, TX; 3Internal Medicine Department, Cairo University Medical school, Cairo, Egypt.

    Background: HCC is commonly associated with viral infections such as HCV & HBV.Aim: To determine whether Hepatitis viral status has impact on survival after OLT…
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