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Articles tagged "Hepatocellular carcinoma"

  • 2017 American Transplant Congress

    Effect of Embolization History and Tumor Treatment Response on Plasma TGFβ in HCC Patients Listed for Liver Transplantation.

    P. Thevenot,1 K. Núñez,1 J. Gonzalez-Rosario,1 T. Sandow,1 A. Alharbi,1 A. Bokhari,1 D. Wyczechowska,2 A. Ochoa,2 A. Cohen.1

    1Multi-Organ Transplant Institute, Ochsner Health System, New Orleans, LA; 2Stanley S Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA

    Purpose: TGFβ signaling is an integral pathway in hepatocellular carcinoma (HCC) metastasis. In this study, we monitored TGFβ levels and imaging response in HCC patients…
  • 2017 American Transplant Congress

    Expanded Criteria for HCC in Liver Transplantation.

    M. Haberal,1 A. Akdur,1 G. Moray,1 G. Arslan,2 F. Ozcay,3 H. Selcuk,4 H. Ozdemir.5

    1General Surgery and Transplantation, Baskent University, Ankara, Turkey; 2Anesthesiology, Baskent University, Ankara, Turkey; 3Pediatric Gastroenterology, Baskent University, Ankara, Turkey; 4Gastroenterology, Baskent University, Ankara, Turkey; 5Pathology, Baskent University, Ankara, Turkey

    Introduction: Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the third highest cause of death related to malignancy. Since HCC diagnosis is…
  • 2017 American Transplant Congress

    Hepatic Artery and Biliary Complications in Liver Transplant Recipients with Radioembolization Bridging Treatment for Hepatocellular Carcinoma.

    S. Radunz,1 J. Treckmann,1 F. Saner,1 S. Müller,2 J. Theysohn,3 A. Paul,1 T. Benkö.1

    1General, Visceral and Transplant Surgery, University Hospital Essen, Essen, Germany; 2Nuclear Medicine, University Hospital Essen, Essen, Germany; 3Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany

    Locoregional treatments are commonly applied in hepatocellular carcinoma (HCC) patients as a bridge to liver transplantation to prevent tumor progression during waiting time. We hypothesized…
  • 2017 American Transplant Congress

    Blockade of Tim-3 and PD-1 Reverses Dysfunctions of Tumor Infiltrating Lymphocytes in HBV Related Hepatocellular Carcinoma.

    A. Hu, F. Liu, X. Zhu, X. He.

    The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    The immunosuppression of tumor infiltrating lymphocytes (TILs) is associated with rapid progress of hepatitis B virus related hepatocellular carcinoma (HBV-HCC). The inhibition molecules of T…
  • 2017 American Transplant Congress

    Different Prognostic Factors for Early and Late Recurrence After Adult Living Donor Liver Transplantation for Hepatocellular Carcinoma.

    S. Hong, K.-W. Lee, H.-S. Kim, S.-W. Ahn, K. Yoon, H. Kim, N.-J. Yi, K.-S. Suh.

    Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea

    Recurrence after liver transplantation (LT) for hepatocellular carcinoma (HCC) remains unsatisfactory. However, some patients with HCC recurrence after LT show good long-term survival results. The…
  • 2017 American Transplant Congress

    Effects of the Gut-Liver Axis on Ischemia-Mediated Hepatocellular Carcinoma Recurrence in the Mouse Liver.

    L. Orci,1 S. Lacotte,1 V. Delaune,1 G. Oldani,1 F. Slits,1 C. Rossetti,2 L. Rubbia-Brandt,3 P. Morel,1 C. Toso.1

    1Hepato-pancreato-biliary Centre, Department of Surgery, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland; 2Dipartimento di Biotecnologie e Scienze della Vita, Università degli Studi dell'Insubria, Varese, Italy; 3Division of Clinical Pathology, Department of Pathology and Immunology, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland

    Background: There is growing evidence that liver graft ischemia-reperfusion (I/R) is a risk factor for hepatocellular carcinoma (HCC) recurrence after liver transplantation, but the involved…
  • 2017 American Transplant Congress

    The Glasgow Prognostic Score and Its Variants Predict Mortality in Living Donor but Not in Deceased Donor Liver Transplantation for Hepatocellular Carcinoma: A Double-Center Validation Study.

    A. Kaltenborn,1 J. Gwiasda,1 N. Heits,2 F. Braun,2 H. Schrem.1

    1Core Facility Quality Management Transplantation, Hannover Medical School, Hannover, Germany; 2Department of General, Visceral-, Thoracic-, Transplantation- and Pediatric Surgery, University Medical Center Schleswig-Holstein, Kiel, Germany

    The notion that inflammation parameters such as CRP and albumin might have an influence on outcome in malignant disease is gaining interest. Serum CRP- and…
  • 2017 American Transplant Congress

    The Beneficial Effects of mTOR Inhibitors on Liver Resident Natural Killer Cells.

    J. Saparbay, Y. Tanaka, T. Yano, H. Ohdan.

    Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan

    (Background) The immunosuppressive regimen currently used after organ transplantation reduces adaptive components. Therefore, the innate immune cells play pivotal roles in immune surveillance and defense…
  • 2017 American Transplant Congress

    Incidental Hepatocellular Carcinoma in Explanted Livers: An Assessment After LIRADS Introduction.

    S. Garcia Aroz,1 D. Ludwig,2 K. Fowler,2 N. Vachharajani,1 M. Xu,1 Y. Lin,1 M. Doyle,1 W. Chapman.1

    1Surgery, Washington University, St. Louis, MO; 2Radiology, Washington University, St. Louis, MO

    Background: Despite new technologies and improvements in imaging diagnosis, incidental and misdiagnosed hepatocellular carcinomas (HCC) are entities that remain present and problematic in liver transplantation.Methods:…
  • 2017 American Transplant Congress

    Proposal for HCC Exception Points to Match Drop Out Risk.

    H. Yeh,3 M. Akan,1 N.-H. Leung,2 J. Markmann,3 S. Tayur.1

    1CMU, Pittsburgh; 2City U, Hong Kong, Hong Kong; 3MGH, Boston

    Background: Recent changes in HCC exception point policy aims to equalize wait list outcomes between HCC and non-HCC patients, but remains dissociated from tumor biology.…
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