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Articles tagged "Hepatocellular carcinoma"

  • 2019 American Transplant Congress

    Outcomes of Liver Transplantation for Mixed Hepatocellular-Cholangiocarcioma

    M. Najjar1, K. Bruestle1, P. Jiang1, S. Robbins-Juarez1, R. Hwang1, A. Mathur1, E. C. Verna1, A. Griesemer1, B. Samstein1, T. Kato1, Y. M. Saenger1, K. J. Halazun2, J. C. Emond1

    1Columbia University Medical Center, New York, NY, 2Weill Cornell Medicine, New York, NY

    *Purpose: Mixed hepatocholangiocarcinomas (HCC-CCA) are rare tumors with both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) differentiations. They are usually associated with a worse prognosis than…
  • 2019 American Transplant Congress

    Resource Utilization in Hepatocellular Carcinoma Liver Transplantation before and after the Six Month Wait Time

    J. Sokolich1, W. McClellan2, J. Buggs1, E. Rogers1, K. Barber1, K. Cocuy1, A. Kumar2

    1Tampa General Hospital, Tampa, FL, 2University of South Florida, Tampa, FL

    *Purpose: The purpose of this study was to determine any difference in resource utilization since the implementation of the mandatory six month wait-time policy for…
  • 2018 American Transplant Congress

    Impact of Mammalian Target of Rapamycin Inhibitors on Hepatocellular Carcinoma Recurrence after Liver Transplant

    N. Hendon,1 D. Salerno,1 C. Sammons,1 K. Halazun.2

    1Pharmacy, NewYork-Presbyterian Hospital, New York, NY; 2Surgery, Weill Cornell Medical College, New York, NY.

    Despite limited benefit to patients within Milan criteria on explant, mTORi are routinely utilized for prevention of hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT).…
  • 2018 American Transplant Congress

    Liver Transplantation for Patients with Hepatocellular Carcinoma Presenting beyond Milan Criteria: Analysis of 789 Patients from the US Multicenter HCC Transplant Consortium

    V. Agopian, United States Multicenter HCC Transplant Consortium.

    UCLA, LA.

    Objective: OPTN has recently approved MELD prioritization for HCC patients beyond Milan Criteria (MC) who are downstaged (DS) with locoregional therapy (LRT) prior to liver…
  • 2018 American Transplant Congress

    Liver Transplantation for Hepatocellular Carcinoma Outperform Other Populations in the New Hepatitis C Era

    A. Alsina,1 A. Athienitis,2 J. Buggs,1 E. Fallon,3 E. Parkinson,3 C. Albers,3 N. Kemmer.3

    1Transplantation Surgery, Tampa General Hospital, Tampa, FL; 2Muma College of Business, University of South Florida, Tamoa, FL; 3Transplant Hepatology, Tampa General Hospital, Tampa, FL.

    Background: Long term results of HCC liver transplants (LTx) in the recent era of direct-acting antivirals (DAA) against hepatitis C (HCV) are not available. We…
  • 2018 American Transplant Congress

    Improving Prognostication amongst Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma: An International, 16-Center Study to Validate and Recalibrate HALTHCC

    D. Firl,1 K. Sasaki,1 S. Kimura,2 W. Dumronggittigule,3 A. Gorgen,4 J. Lerut,5 M. Rossi,6 U. Cillo,7 A. Viveiros,8 E. Tsochatzis,9 G. Otto,10 G. Ettorre,11 G. Tisone,12 M. Vivarelli,13 S. Agnes,14 J. Markmann,2 T. Ikegami,15 T. Kaido,16 G. Sapisochin,4 V. Agopian,3 Q. Lai,5,6 F. Aucejo.1

    1CCF, Cleveland; 2MGH, Boston; 3UCLA, LA; 4UHN, Toronto, Canada; 5SLH, Louvain, Belgium; 6UH, Rome, Italy; 7UP, Padua, Italy; 8MUI, Innsbruck, Austria; 9UCL, London, United Kingdom; 10UM, Mainz, Germany; 11SCH, Rome, Italy; 12TVU, Rome, Italy; 13AOU, Torrette Ancona, Italy; 14AGH, Rome, Italy; 15KU, Kyoto, Japan; 16KU, Kyushu, Japan.

    Objective: Prognosticating outcomes in liver transplant (LT) for hepatocellular carcinoma (HCC) continues to challenge the field. Whereas adoption of the binary Milan Criteria (MC) generalized…
  • 2018 American Transplant Congress

    Predictive Value of mRECIST in HCC Response to the Neoadjuvant Locoregional Therapies and Prognosis Affected by the Peak AFP Level before Liver Transplantation

    M. Xu,1 T. Fraum,2 S. Garcia-Aroz,1 N. Vachharajani,1 N. Saad,3 K. Fowler,2 Y. Lin,1 W. Chapman.1

    1Department of Surgery, Section of Abdominal Transplantation, Washington University School of Medicine, St. Louis, MO; 2Department of Radiology, Washington University School of Medicine, St. Louis, MO; 3Department of Imaging Sciences, University of Rochester Medical Center, Rochester, NY.

    PURPOSE: The modified response evaluation criteria in solid tumors (mRECIST) has been used to assess the response of hepatocellular carcinoma (HCC) to locoregional therapy (LRT)…
  • 2018 American Transplant Congress

    HLA-DR4 Matching and Hepatocellular Carcinoma Recurrence after Liver Transplantation

    M. Xu, S. Garcia-Aroz, N. Vachharajani, Y. Lin, W. Chapman.

    Department of Surgery, Section of Abdominal Transplantation, Washington University School of Medicine, St. Louis, MO.

    PURPOSE: The phenomenon of graft versus host disease after orthotopic liver transplantation (OLT) is estimated at approximately 1-2%, suggesting that under some circumstances, the graft…
  • 2018 American Transplant Congress

    Vascular Invasion and Survival after Liver Transplantation for Hepatocellular Carcinoma: A Study from the European Liver Transplant Registry

    H-.C. Pommergaard, A. Rostved, R. Adam, L. Thygesen, M. Salizzoni, M. Bravo, D. Cherqui, F. Filipponi, K. Boudjema, V. Mazzaferro, O. Soubrane, J. García-Valdecasas, J. Prous, A. Pinna, J. O'Grady, V. Karam, C. Duvoux, A. Rasmussen.

    Rigshospitalet, Copenhagen, Denmark; Rigshospitalet, Copenhagen, Denmark; Hôpital Universitaire Paul Brousse, Villejuif, France; National Institute of Public Health, Copenhagen, Denmark; A.O.U. Città della Salute e della Scienza di Torino, Turin, Italy; Hospital Virgen del Rocio, Sevilla, Spain; Hôpital Universitaire Paul Brousse, Villejuif, France; University of Pisa Medical School Hospital, Pisa, Italy; Hôpital Pontchaillou, Rennes, France; Istituto Nazionale Tumori, Milan, Italy; Beaujon Hospital, Clichy, France; Hospital Clínic, Barcelona, Spain; Hospital Universitari de Bellvitge, Barcelona, Spain; S. Orsola Hospital, Bologna, Italy; King's College Hospital, London, United Kingdom; Hôpital Universitaire Paul Brousse, Villejuif, France; Henri Mondor Hospital, Créteil, France; Rigshospitalet, Copnehagen, Denmark.

    PurposeStudies suggest that vascular invasion may be a superior prognostic marker compared with traditional selection criteria, e.g. Milan criteria. We aimed to investigate the prognostic…
  • 2018 American Transplant Congress

    Post-Transplant Outcomes under the New HCC Exception Policy

    T. Ishaque, A. Massie, C. Haugen, D. Segev.

    Surgery, Johns Hopkins Medical Institute, Baltimore, MD.

    In October 2015, OPTN implemented a new policy for liver allocation, under which hepatocellular carcinoma (HCC) patients receive exception points only after a 6-month delay.…
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