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Articles tagged "Hepatitis"

  • 2019 American Transplant Congress

    Introduction of Universal Hepatitis E RNA Screening in Deceased Organ Donors – The UK Experience

    I. Ushiro-Lumb1, K. Tettmar1, I. Johannessen2, K. Simpson2, I. Hart3, J. Timms4, A. Hale5, S. Ijaz6, R. Tedder6, J. Forsythe1

    1NHS Blood and Transplant, London, United Kingdom, 2Royal Infirmary of Edinburgh, Edinburgh, United Kingdom, 3Royal Liverpool University Hospital, Liverpool, United Kingdom, 4University Hospitals Coventry and Warwickshire, Coventry, United Kingdom, 5Public Health England, Leeds, United Kingdom, 6Public Health England, London, United Kingdom

    *Purpose: We aim to describe the strategy and initial results of post-donation, universal screening of deceased organ donors in the UK. HEV RNA is tested…
  • 2018 American Transplant Congress

    Impact of Early Corticosteroid Treatment in Patients with Indeterminate Acute Severe Hepatitis

    E. Mohr,1 R. Sucher,2 T. Müller,3 T. Kaiser,4 T. Berg.1

    1Hepatology, University Clinic Leipzig, Leipzig, Germany; 2Transplant Surgery, University Clinic Leipzig, Leipzig, Germany; 3Hepatology, Charite, Berliin, Germany; 4Laboratory Diagnostics, University Clinic Leipzig, Leipzig, Germany.

    Background and Aims: Discrimination of acute severe autoimmune hepatitis AIH and drug induced liver injury in patients with indeterminate acute severe Hepatitis is challenging. Early…
  • 2017 American Transplant Congress

    Hepatitis E Virus-Associated Cryoglobulinemia in Solid-Organ-Transplant Recipients: A Prospective Study.

    O. Marion,1 F. Abravanel,2 L. Esposito,1 S. Lhomme,2 A. Del Bello,1 J. Izopet,2 N. Kamar.1

    1Nephrology and Organ Transplant Unit, CHU Rangueil, Toulouse, France; 2Laboratory of Virology, CHU Purpan, Toulouse, France

    Hepatitis E virus (HEV) is responsible for acute and chronic autochthonous hepatitis in developed countries, particularly in Western Europe. Conversely to hepatitis B or C,…
  • 2017 American Transplant Congress

    Risk Factor for Hepatitis E Virus Infection Among Solid-Organ-Transplant Patients.

    N. Kamar,1 S. Lhomme,2 F. Abravanel,2 L. Esposito,1 A. Hebral,1 O. Marion,1 A. Del Bello,1 J. Izopet.2

    1Department of Nephrology and Organ Transplantation, Toulouse University Hospital, Toulouse, France; 2Department of Virology, Toulouse University Hospital, Toulouse, France

    Genotype 3 and 4 hepatitis E virus (HEV) infections are prevalent in developed countries and can cause chronic hepatitis, cirrhosis, and extra-hepatic manifestations among solid-organ-transplant…
  • 2016 American Transplant Congress

    Review of Organ Utilization from Increased Infectious Risk Donors.

    A. L'Huillier,1 A. Humar,2 C. Payne,3 D. Kumar.2

    1Division of Infectious Diseases, Hospital for Sick Children and University of Toronto, Toronto, Canada; 2Transplant Infectious Diseases and Multi-Organ Transplant Program, University Health Network, Toronto, Canada; 3Trillium Gift of Life Network, Toronto, Canada.

    IntroductionDonors with an increased risk of transmitting HIV, HBV or HCV (IRDs) are a potential source of organs. There is a lack of data on…
  • 2016 American Transplant Congress

    Long Term Outcome of De-Novo Autoimmune Hepatitis in Pediatric Recipients of Liver Transplantation.

    Y. Avitzur,1 P. McKiernan,2 M. Martinez,3 S. Lobritto,3 D. Kelly,2 V. Ng,1 E. Alonso,4 U. Ekong.5

    1Hospital for Sick Children, Toronto, Canada; 2Birmingham Children's Hospital, Birmingham, United Kingdom; 3Morgan Stanley Children's Hospital, New York; 4Lurie Children's Hospital, Chicago; 5Yale New Haven Children's Hospital, New Haven.

    Background: De-novo autoimmune hepatitis (DAIH) is a chronic immune mediated graft disorder seen following liver transplantation (LT). The long-term course and outcome of DAIH is…
  • 2016 American Transplant Congress

    Ledipasvir/Sofosbuvir (LDV/SOF) for 12 or 24 Weeks Is Safe and Effective in Kidney Transplant Recipients with Chronic Genotype 1 or 4 HCV Infection.

    S. Pol,1 A. Aghemo,2 L. Lin,3 R. Hyland,3 C. Yun,3 J. Spellman,3 M. Natha,3 D. Brainard,3 J. McHutchison,3 M. Bourlière,4 M. Peck-Radosavljevic,6 M. Michael,5 M. Colombo.2

    1Hopital Cochin, Paris, France; 2Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; 3Gilead Sciences Inc, Foster City; 4Hôpital Saint Joseph, Marseilles, France; 5Hannover Medical School, Hannover, Germany; 6Medical University of Vienna, Vienna, Austria.

    Background and Aims: Interferon (IFN) and ribavirin (RBV) for the treatment of chronic hepatitis C (HCV) in kidney transplant recipients is complicated by the risk…
  • 2015 American Transplant Congress

    The Impact of the New Antivirals Sofosfuvir/Ledipasvir on Liver Transplantation for Hepatitis C Cirrhosis

    S. Munoz,1 D. Reich,2 K. Rothstein.1

    1Div of Hepatology, Liver Failure Unit, Hanemann University Hospital, Philadelphia, PA; 2Liver, Kidney and Pancreas Transplant Program, Hahnemann University Hospital, Philadelphia, PA.

    The approval of potent antiviral therapy (AVT) with sofosfuvir/ledipasvir (sof/ldv) for hepatitis C (HCV) dramatically increased cure rates (SVR) to nearly 100%. A recent prospective…
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