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Articles tagged "Hepatitis C"

  • 2020 American Transplant Congress

    Liver Transplantation of Hepatitis C Viremic Donors to Hepatitis C Naive Recipients

    R. K. Gilroy, F. Lopez-Verdugo, G. Harmston, S. Fujita, M. E. Boschert, I. Zendejas, E. J. Frech, A. Gagnon, R. Jones, J. Krong, S. Sell, S. Dow, L. Lindberg, M. Rodriguez-Davalos, D. Alonso

    Transplant Services, Intermountain Healthcare, Murray, UT

    *Purpose: This study describes outcomes, out to 3 years, at one of the first centers in the United States to begin Hepatitis C Virus (HCV)-Nucleic…
  • 2020 American Transplant Congress

    The Economic Impact of HCV D+/R- Kidney Transplantation

    S. Meade1, M. A. Simpson2, E. D. Walshe1, M. E. Akoad2, F. D. Gordon2

    1Lahey Clinic, Burlington, MA, 2Transplantation, Lahey Clinic, Burlington, MA

    *Purpose: In September 2018, we began offering carefully screened kidney transplant candidates the opportunity for transplantation with kidneys from hepatitis C (HCV) positive deceased donors.…
  • 2020 American Transplant Congress

    The Clinical Impact of HCV D+/r- Kidney Transplantation

    S. Meade1, M. A. Simpson2, E. D. Walshe2, M. E. Akoad2, F. D. Gordon2

    1Lahey Clinic, Burlington, MA, 2Transplantation, Lahey Clinic, Burlington, MA

    *Purpose: Transplantation of hepatitis C (HCV) positive organs into HCV negative recipients raises concerns regarding potential for infections unresponsive to DAAs. In September 2018, we…
  • 2020 American Transplant Congress

    The Effect of Pulsatile Pump Perfusion on Hepatitis C Viremia and Transmission in Kidney Transplantation: A Prospective Pilot Study

    R. Forbes1, B. Concepcion1, D. Clapper2, B. Dubray1, A. Miller2, D. Shaffer1, K. Johnson2

    1Vanderbilt University Medical Center, Nashville, TN, 2Tennessee Donor Services, Nashville, TN

    *Purpose: With increasing utilization of hepatitis C (HCV) viremic donor organs for aviremic recipients, there may be a role for kidney pulsatile pump perfusion to…
  • 2020 American Transplant Congress

    Effect of Glecaprevir/Pibrentasvir on Weight-Adjusted Tacrolimus Trough/Dose Ratios in Heart and Kidney Recipients

    D. Nnani1, A. Campbell1, M. Ajaimy2, S. R. Patel3, O. Saeed3, D. J. Goldstein4, J. Graham5, U. P. Jorde3

    1Pharmacy, Montefiore Medical Center, Bronx, NY, 2Medicine, Montefiore Medical Center, Bronx, NY, 3Division of Cardiology, Department of Medicine, Montefiore Medical Center, Bronx, NY, 4Cardiothoracic Surgery, Montefiore Medical Center, Bronx, NY, 5Surgery, Montefiore Medical Center, Bronx, NY

    *Purpose: An innovative strategy to meet the demands of patients requiring heart or kidney transplantation is the acceptance of hepatitis C viremic organs. Direct acting…
  • 2020 American Transplant Congress

    Utilization of Organs from Donors Exposed to Hepatitis C: ? Standard of Care

    M. Marvin1, S. Gaines2, P. Mohan3, A. Kotru1, C. Koo1, B. Addissie4, A. Unzueta4, S. Khurana4

    1Transplantation and Liver Surgery, Geisinger, Danville, PA, 2Pharmacy, Geisinger, Danville, PA, 3Nephrology, Geisinger, Danville, PA, 4Hepatology, Geisinger, Danville, PA

    *Purpose: To report the results of a clinical program to utilize livers and kidneys from donors exposed to Hepatitis C.*Methods: We initially started to explore…
  • 2020 American Transplant Congress

    Multi-Organ Procurement Organization Review of the Impact of Reactive Anti-HCV and HCV NAT Results

    C. C. Muse, C. A. Hostetler, R. A. Squires, J. P. Orlowski

    LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK

    *Purpose: Previously a single organ procurement organization (OPO) reviewed data from a 15 month cohort (1/1/2016 to 3/31/17) and concluded that donors who tested positive…
  • 2020 American Transplant Congress

    Utilization of Kidneys from Deceased Donors with Positive Hepatitis C Nucleic Acid Amplification Testing (HCV NAT+)

    K. L. King, S. A. Husain, S. Mohan

    Columbia University, New York, NY

    *Purpose: With modern direct-acting antiviral agents, transplantation of kidneys from HCV NAT+ deceased donors for recipients with or without HCV has expanded the kidney supply.…
  • 2020 American Transplant Congress

    Evaluating the Effect of HCV Status on the KDPI in the Era of DAA Therapy

    J. Husson1, S. Curreli2, B. Ravichandran3, E. Wilson4

    1Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, 2Institute of Human Virology, Baltimore, MD, 3University of Maryland Medical Center, University of Maryland School of Pharmacy, Baltimore, MD, 4Institue of Human Virology, University of Maryland School of Medicine, Baltimore, MD

    *Purpose: The association between KDPI and kidney graft outcomes is limited in the era of DAA therapy.*Methods: We analyzed adult renal transplants, at the University…
  • 2020 American Transplant Congress

    Viral Kinetics of De Novo HCV Infection and Response to Antiviral Therapy in Liver and Kidney Transplant Recipients Receiving HCV-Viremic Donors

    N. Terrault1, J. Burton2, E. Verna3, C. Mobley4, D. Victor4, J. Trotter5, C. Niemann6, R. Rubin7

    1University of Southern California, Los Angeles, CA, 2UC, Denver, CO, 3Columbia Universeity, New York, NY, 4Houston Methodist, Houston, TX, 5Baylor University, Dallas, TX, 6UCSF, San Francisco, CA, 7Piedmont Atlanta Hosptial, Atlanta, GA

    *Purpose: There is general agreement that expanded use of organs from HCV-viremic donors is desirable, including in recipients without HCV infection. However, the optimal treatment…
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