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American Transplant Congress abstracts

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Articles tagged "Hepatitis C"

  • 2017 American Transplant Congress

    Kidney Transplantation in HCV+ Recipients in a New Era of Diagnostics and Therapeutics.

    C. Traynor, S. Bumb, C. Berg, M. Ellis, J. Roberts, A. Muir, L. King, C. Brady, S. Sanoff.

    Duke University Medical Center, Durham, NC

    BackgroundHepatitis-C infected persons (HCV+) evaluated for kidney transplantation receive rigorous staging of their liver disease, often including liver biopsy. Meanwhile, studies have shown that despite…
  • 2017 American Transplant Congress

    The Safety and Efficacy of Directly-Acting Antivirals with or without Ribavirin for HCV Genotype 1 Infection: A Systematic Review and Meta-Analysis.

    Z. Guo, J. Gu, X. He, G. Chen.

    The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Previous studies have reported that ribavirin-free regimens are effective for treating chronic hepatitis C virus genotype 1 infection. However, the efficacy and safety of ribavirin-free…
  • 2017 American Transplant Congress

    Willingness of End-Stage Renal Disease Patients (ESRD) without Hepatitis C (HCV) to Accept a HCV+ Kidney.

    P. Reese,1 D. Goldberg,1 A. Mussell,1 M. McCauley,1 D. Sawinski,1 N. Molina,2 R. Tomlin,2 S. Doshi,1 P. Abt,1 E. Blumberg,1 C. Thiessen,2 S. Kulkarni,2 G. Esnaola.2

    1UPENN, Philadelphia, PA; 2Yale, New Haven, CT

    Background: New HCV drugs could reduce the risks of donor-derived HCV infection. However, it is unknown if HCV-negative (HCV-) ESRD patients would accept an HCV+…
  • 2017 American Transplant Congress

    Direct Acting Antiviral Drugs Are Highly Effective in Hepatitis C (HCV) Patients with End Stage Renal Disease (ESKD) and Advanced Liver Disease (ALD).

    J. Korula, T. Shah, E. Ranger, E. Barba, D. Vu, R. Naraghi.

    Multi Transplant Organ Center, St Vincent Medical Center, Los Angeles, CA

    Reports of efficacy of Direct Acting Antiviral drugs (DAA) > 90% in treatment of chronic HCV genotype 1, [GT1, 12 wk Sustained Viral Response (SVR12)]…
  • 2017 American Transplant Congress

    Ambiguous Nucleic Acid Tests (NAT) Results – Case of a Donor with Intermittent HCV NAT(+) but No HCV Transmission.

    M. Nowicki,1,2 H. Prince,2 C. Chinchilla,2 C. De Los Santos,2 J. Trageser,3 L. Stocks.3

    1Mendez National Institute of Transplantation Foundation, Los Angeles, CA; 2VRL-Eurofins, Los Angeles, CA; 3Lifesharing OPO, San Diego, CA

    Background Less than 0.2 % of initially NAT(+) upon retesting are reported as NAT negative. However, there is a concern that these results could be…
  • 2017 American Transplant Congress

    Assessment of Attitudes Toward Use of Hepatitis C Positive Liver Allografts in US Transplant Centers.

    S. Kilaru,1 E. Tapper,2 M. Curry.3

    1Medicine, NYU School of Medicine, New York, NY; 2Medicine, University of Michigan, Ann Arbor, MI; 3Medicine, Beth Israel Deaconess Medical Center, Boston, MA

    Background:Direct-acting antivirals (DAAs) have been shown to have high cure rates in hepatitis C (HCV)-positive liver transplantation (LT) recipients. The organ donor shortage has led…
  • 2017 American Transplant Congress

    Nonmelanoma Skin Cancer Rates Are Not Affected by Chronic HIV(+) or HCV(+) Infection in Organ Transplant Recipients.

    K. Nadhan, E. Usedom, S. Shipman, A. Doyle, G. Malat, E. Buchanan, C. Chung.

    Dermatology, Drexel, Philadelphia

    Purpose: HIV and HCV are two immune dysregulatory processes that may exacerbate the risk of nonmelanoma skin cancer (NMSC) in organ transplant recipients (OTR), a…
  • 2017 American Transplant Congress

    A Multi-Center Experience of Direct Acting Anti-Viral Agents in HCV Positive Patients Receiving HCV Positive Livers.

    N. Kapila,1 B. Zervos,2 B. Ismail,1 C. Lindenmeyer,3 V. Sanghi,3 K. Menon,3 G. Schnickel,2 J. Rivas,2 D. Reino,2 A. Tzakis.2

    1Gastroenterology, Cleveland Clinic, Weston, FL; 2Transplant, Cleveland Clinic, Weston, FL; 3Gastroenterology, Cleveland Clinic, Cleveland, OH

    Background: HCV cirrhosis is the leading indication for liver transplantation in the U.S. The development of direct acting anti-viral agents (DAAs) has changed the approach…
  • 2017 American Transplant Congress

    A Single Center's Experience of Direct Acting Anti-Viral Agents in HCV Positive Patients Receiving an HCV Positive Kidney.

    N. Kapila,1 B. Zervos,2 B. Ismail,1 G. Schnickel,2 J. Rivas,2 D. Reino,2 N. Agrawal,2 A. Tzakis.2

    1Gastroenterology/Hepatology, Cleveland Clinic, Weston, FL; 2Transplant, Cleveland Clinic, Weston, FL

    Background: Nearly 8% of patients in the U.S. undergoing hemodialysis are Hepatitis C (HCV) positive. There is a survival benefit in HCV positive patients who…
  • 2017 American Transplant Congress

    Does Cirrhosis Regress in HCV Liver Transplant Recipients Achieving Sustained Virologic Response in the Era of Direct-Acting Antiviral Agents?

    J. Putra,1 T. Schiano,2 M. Fiel.1

    1Pathology, Icahn School of Medicine at Mount Sinai, New York, NY; 2Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY

    Background: Treatment with direct-acting antiviral agents (DAAs) in HCV patients is associated with high sustained virologic response (SVR) rates. It is hoped that cirrhosis regresses…
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