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Articles tagged "Hepatitis C"

  • 2018 American Transplant Congress

    Impact of Direct Acting Antiviral Agents (DAAs) for Hepatitis C Virus (HCV)-Induced Liver Diseases on Registration and Outcome on Waiting List (WL) for Liver Transplant (LT)

    C. Antoine,1 C. Jasseron,1 F. Conti,2 S. Dharancy,3 C. Duvoux,4 A. Coilly.5

    1Medical and Scientific Department, Agence de la Biomedecine, Agence de la Biomedecine, La Plaine Saint Denis, Saint Denis, France; 2Department of Hepatology, University Hospital La Pitie, Paris, France; 3Department of Hepatology, University Hospital Huriez, Lille, Nord Pas de Calais, France; 4Department of Hepatology, University Hospital Henri Mondor, Créteil, Val de Marne, France; 5Department of Hepatology, University Hospital Paul Brousse, Villejuif, Val de Marne, France.

    2d-generation DAAs have dramatically improved the management of patients with HCV, including patients with advanced diseases. In France, since 2013, DAA have been largely used,…
  • 2018 American Transplant Congress

    Impact of Direct Antiviral Therapy for Hepatitis C on Acute Rejection and DSA Formation in Kidney Transplant Recipients

    Z. Zaky, S. Armanyous, L. Herlitz, E. Poggio, J. Augustine.

    Cleveland Clinic, Cleveland, OH.

    Background: Hepatitis C virus infection (HCV) has historically portended a poor outcome after kidney transplantation. With recent advent of direct antiviral agents (DAA), there has…
  • 2018 American Transplant Congress

    Impact of Direct Acting Antivirals of Hepatitis C Virus Therapy on Tacrolimus Dosing Post-Liver Transplant

    A. Bixby, L. Fitzgerald, R. Leek, J. Mellinger, S. Tischer.

    Michigan Medicine, Ann Arbor, MI.

    Background: Direct acting antivirals (DAA) have transformed hepatitis C virus (HCV) management post-liver transplant (LT). As HCV clears, hepatic metabolism improves, resulting in decreased tacrolimus…
  • 2018 American Transplant Congress

    Safety and Efficacy of Sofosbuvir-Based Direct-Acting Antiviral Agents in Kidney Transplant Recipients with HCV: A Systematic Review and Meta-Analysis

    X. Wang,1 P. Tan,1 T. Xiang,2 Y. Qiu,1 T. Song,1 T. Lin.1

    1Department of Urology/Institute of Urology/Organ Transplantation Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; 2West China School of Clinical Medicine, Sichuan University, Chengdu, Sichuan Province, China.

    Background: Outcome data on sofosbuvir (SOF)-based therapy in patients with kidney transplantation (KTx) with hepatitis C virus infection are limited with individual studies having a…
  • 2018 American Transplant Congress

    Private Insurance is Associated with Reduce Access to HCV Therapy after Liver Transplantation

    D. Axelrod,1 M. Schnitzler,2 B. Kasiske,3 G. Hess,4 R. Bloom,5 F. Gordon,1 H. Randall,2 K. Lentine.2

    1Lahey Clinic, Burlington; 2Saint Louis U, St. Louis; 3SRTR, Minneapolis; 4Symphony Health, Conshohocken; 5U Penn, Philadelphia.

    Effective treatment for hepatitis C virus (HCV) infection has revolutionized post liver transplant (LTx) care. Administration of direct-acting antiviral agents (DAAs) after HCV+ LTx results…
  • 2018 American Transplant Congress

    Elbasvir-Grazoprevir (Zepatier) is Effective and Safe for the Treatment of Chronic Hepatitis C (HCV) Genotype 1 Virus in the Post Kidney Transplant Patient

    P. Brown, D. Venkat.

    Henry Ford Hospital, Detroit.

    Objective: Limited real world data exists regarding the use of direct acting antivirals (DAA) for HCV viremia in renal transplant patients, particularly those with marked…
  • 2018 American Transplant Congress

    Incidence of Acute Cellular Rejection in Liver Transplant Patients Receiving Direct Acting Antivirals for Hepatitis C Treatment

    D. Bley,1 L. Sagardia,1 R. Ford,2 S. Todd.1

    1Pharmacy, Emory University Hospital, Atlanta, GA; 2School of Medicine, Emory University, Atlanta, GA.

    Direct acting antivirals (DAAs) have been used for the treatment of hepatitis C (HCV) in liver transplant patients since early on after their approval, however…
  • 2018 American Transplant Congress

    One-Year Outcomes in Patients with Advanced Liver Fibrosis or Compensated Cirrhosis from Chronic Hepatitis C Receiving Kidney Transplant Alone

    P. Brown, F. Kumssa, D. Venkat.

    Henry Ford Hospital, Detroit.

    Background: Hepatitis C (HCV) was difficult to treat post-kidney transplant prior to the direct acting antiviral (DAA) era. As such patients with advanced fibrosis and…
  • 2018 American Transplant Congress

    Cost Effectiveness of Hepatitis C Positive Donor Kidney Transplantation for Hepatitis C Negative Recipients with Concomitant Direct-Acting Anti-Viral Therapy

    G. Gupta, Y. Zhang, H. Kale, N. Carroll, R. Sterling.

    Virginia Commonwealth University, Richmond.

    Background: The development of direct acting antiviral (DAA) therapy for hepatitis C virus (HCV) could allow for safe and effective treatment following renal transplantation (RT).…
  • 2018 American Transplant Congress

    Treatment of HCV Infection in Renal Transplant Recipients

    M. Rial, L. Tana, C. Alonso, H. Curcio, E. Chulluyan, D. Casadei.

    Renal Transplant Unit, Instituto de Nefrologia Nephrology, Buenos Aires, Argentina.

    HCV infection is associated to chronic hepatitis, cirrhosis, hepatic carcinoma and increased incidence of diabetes. Combination of new antiviral drugs have demonstrated utility in liver…
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