ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Hepatitis C"

  • 2020 American Transplant Congress

    Effect of Glecaprevir/Pibrentasvir on Weight-Adjusted Tacrolimus Trough/Dose Ratios in Heart and Kidney Recipients

    D. Nnani1, A. Campbell1, M. Ajaimy2, S. R. Patel3, O. Saeed3, D. J. Goldstein4, J. Graham5, U. P. Jorde3

    1Pharmacy, Montefiore Medical Center, Bronx, NY, 2Medicine, Montefiore Medical Center, Bronx, NY, 3Division of Cardiology, Department of Medicine, Montefiore Medical Center, Bronx, NY, 4Cardiothoracic Surgery, Montefiore Medical Center, Bronx, NY, 5Surgery, Montefiore Medical Center, Bronx, NY

    *Purpose: An innovative strategy to meet the demands of patients requiring heart or kidney transplantation is the acceptance of hepatitis C viremic organs. Direct acting…
  • 2020 American Transplant Congress

    Utilization of Organs from Donors Exposed to Hepatitis C: ? Standard of Care

    M. Marvin1, S. Gaines2, P. Mohan3, A. Kotru1, C. Koo1, B. Addissie4, A. Unzueta4, S. Khurana4

    1Transplantation and Liver Surgery, Geisinger, Danville, PA, 2Pharmacy, Geisinger, Danville, PA, 3Nephrology, Geisinger, Danville, PA, 4Hepatology, Geisinger, Danville, PA

    *Purpose: To report the results of a clinical program to utilize livers and kidneys from donors exposed to Hepatitis C.*Methods: We initially started to explore…
  • 2020 American Transplant Congress

    Multi-Organ Procurement Organization Review of the Impact of Reactive Anti-HCV and HCV NAT Results

    C. C. Muse, C. A. Hostetler, R. A. Squires, J. P. Orlowski

    LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK

    *Purpose: Previously a single organ procurement organization (OPO) reviewed data from a 15 month cohort (1/1/2016 to 3/31/17) and concluded that donors who tested positive…
  • 2020 American Transplant Congress

    Utilization of Kidneys from Deceased Donors with Positive Hepatitis C Nucleic Acid Amplification Testing (HCV NAT+)

    K. L. King, S. A. Husain, S. Mohan

    Columbia University, New York, NY

    *Purpose: With modern direct-acting antiviral agents, transplantation of kidneys from HCV NAT+ deceased donors for recipients with or without HCV has expanded the kidney supply.…
  • 2020 American Transplant Congress

    Evaluating the Effect of HCV Status on the KDPI in the Era of DAA Therapy

    J. Husson1, S. Curreli2, B. Ravichandran3, E. Wilson4

    1Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, 2Institute of Human Virology, Baltimore, MD, 3University of Maryland Medical Center, University of Maryland School of Pharmacy, Baltimore, MD, 4Institue of Human Virology, University of Maryland School of Medicine, Baltimore, MD

    *Purpose: The association between KDPI and kidney graft outcomes is limited in the era of DAA therapy.*Methods: We analyzed adult renal transplants, at the University…
  • 2020 American Transplant Congress

    Viral Kinetics of De Novo HCV Infection and Response to Antiviral Therapy in Liver and Kidney Transplant Recipients Receiving HCV-Viremic Donors

    N. Terrault1, J. Burton2, E. Verna3, C. Mobley4, D. Victor4, J. Trotter5, C. Niemann6, R. Rubin7

    1University of Southern California, Los Angeles, CA, 2UC, Denver, CO, 3Columbia Universeity, New York, NY, 4Houston Methodist, Houston, TX, 5Baylor University, Dallas, TX, 6UCSF, San Francisco, CA, 7Piedmont Atlanta Hosptial, Atlanta, GA

    *Purpose: There is general agreement that expanded use of organs from HCV-viremic donors is desirable, including in recipients without HCV infection. However, the optimal treatment…
  • 2020 American Transplant Congress

    Transplanting Livers from Hepatitis C Virus Positive Donors; Is it Worth the Risk?

    J. W. Mensink1, B. Van Hoek2, B. Schaefer3, M. D. Van Rosmalen4, I. P. Alwayn5, A. E. Braat5

    1Leiden University Medical Center, Leiden, Netherlands, 2Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands, 3Dutch Transplant Foundation, Leiden, Netherlands, 4Eurotransplant International Foundation, Leiden, Netherlands, 5Transplant Surgery, Leiden University Medical Center, Leiden, Netherlands

    *Purpose: Before the introduction of Direct-Acting Antivirals (DAAs), only selected organs from Hepatitis C virus (HCV) positive donors were successfully transplanted into HCV positive recipients.…
  • 2020 American Transplant Congress

    Hepatitis C Antibody Seroconversion in Kidney Transplant Patients from HCV Antibody Positive/NAT Negative Donors Does Not Deteriorate Renal Allograft Outcome

    R. Rattanavich, M. De Vera, T. Hoang, R. Villicana

    Loma Linda University, Transplant Institute, San Bernadino, CA

    *Purpose: Prior studies have shown that almost 50% of kidney transplant patients from hepatitis C Ab+/NAT - donors have seroconverted but its impact on renal…
  • 2020 American Transplant Congress

    HCV Viremic Kidneys for Uninfected Recipients with DAA Treatment Offers Sustained Virologic Response

    J. Torabi, A. Montal, M. Ajaimy, L. Lirano, Y. Azzi, C. Pynadath, E. Akalin, J. Melvin, M. Kinkhabwala, S. Greenstein, J. P. Rocca, J. A. Graham

    Montefiore Medical Center, Bronx, NY

    *Purpose: Development of direct acting anti-viral medications (DAA) have offered cure rates for hepatitis C infection (HCV) approaching 100%. This has provided the ability to…
  • 2020 American Transplant Congress

    Real-World Experiences in the Transplantation of Hepatitis C Positive Kidneys

    J. M. Steinbrink, J. Byrns, L. Crona, M. Ellis, S. Sanoff, E. K. Maziarz, C. R. Wolfe

    Duke University, Durham, NC

    *Purpose: With advancements of direct-acting antivirals, transplantation of HCV-NAT+ (HCV+) organs to HCV-negative (HCV-) recipients has been used to decrease wait times without apparent sacrifice…
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