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Articles tagged "Hemolytic-uremic syndrome"

  • 2016 American Transplant Congress

    Management of Recurrent aHUS After Adult Kidney transplantation Despite Eculizumab Prophylaxis.

    M. Morton,1 R. Chinnadurai,1 S. Ahmed,2 A. Sharma,2 T. Dutt,2 S. Bhutani,1 H. Denley,1 T. Augustine,1 T. Goodship,3 N. Sheerin,3 M. Picton.1

    1Renal Transplant Unit, Manchester Royal Infirmary, Manchester, United Kingdom; 2Royal Liverpool Hospital, Liverpool, United Kingdom; 3Freeman Hospital, Newcastle, United Kingdom.

    Background Eculizumab (EZB) is approved by NHSE in the UK for prevention and managment of recurrent aHUS after kidney transplantation. Purpose We report aggressive recurrence…
  • 2016 American Transplant Congress

    Thrombotic Microangiopathy After Kidney Transplantation: A Rare but Serious Complication.

    C. Teixeira, I. Pietrobom, A. Lima, N. Tenório, G. Basso, M. Cristelli, L. Viana, G. Kirsztajn, H. Tedesco-Silva, J. Medina-Pestana.

    Universidade Federal de São Paulo, São Paulo, Brazil.

    Purposes: Study the clinical characteristics of cases with thrombotic microangiopathy (TMA) in the renal allograft, identify the triggers of this disease and determine its impact…
  • 2015 American Transplant Congress

    Characteristics and Outcomes of Renal Transplant Recipients With Hemolytic Uremic Syndrome: An OPTN Registry Analysis

    B. Tanriover,1 M. MacConmara,2 R. Saxena,1 Y.-M. Shen.3

    1Medicine/Nephrology, UT Southwestern, Dallas, TX; 2Surgery, UT Southwestern, Dallas, TX; 3Medicine/Hematology, UT Southwestern, Dallas, TX.

    Hemolytic uremic syndrome (HUS) accounts for <1% of renal transplants in the US. There is limited data on the characteristics and outcomes of in pediatric…
  • 2015 American Transplant Congress

    1-Year Safety and Efficacy of Eculizumab in Adult aHUS Patients, With or Without a History of Renal Transplant

    C. Legendre,1 J. Kincaid,2 C. Bedrosian,2 C. Loirat.3

    1University Paris Descartes & Hôpital Necker, Paris, France; 2Alexion, Cheshire, CT; 3Assistance Publique–Hôpitaux Paris, Hôpital Robert-Debré, Paris, France.

    Background: Atypical hemolytic-uremic syndrome (aHUS) is a life-threatening, chronic disease of complement-mediated TMA. In aHUS, renal transplantation is associated with post-transplant (TP) TMA and ∼50–70%…
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