Articles tagged "Heart transplant patients"

2021 American Transplant Congress
Management of Drug Interactions During Protocolized Implementation of Posaconazole Immediately Post Heart Transplant
G. Waldman, C. Rogers Marks, J. Clark, A. Woo, L. Irwin, A. Gerlach, G. D. Lewis, J. A. Fishman
Massachusetts General Hospital, Boston, MA
*Purpose: Posaconazole (POSA) is a strong CYP3A4 inhibitor known to increase tacrolimus exposure by up to 4-fold. Initiation requires empiric tacrolimus dose adjustment and close…
2021 American Transplant Congress
Primary Graft Dysfunction in a Risk-Stratified vs. Routine Induction Protocol in Heart Transplant Recipients
J. S. van Zyl¹, H. Zafar¹, P. M. Nguyen², J. Felius¹, T. Sam³, S. A. Hall³
¹Baylor Scott & White Research Institute, Dallas, TX, ²Texas A&M University College of Medicine Health Science Center, Dallas, TX, ³Baylor Scott & White Health, Dallas, TX
*Purpose: Treatment of left ventricular primary graft dysfunction (PGD-LV) is supportive in nature. We aim to evaluate whether a change in induction protocol from a…
2021 American Transplant Congress
Pregnancy Outcomes in 108 Heart Transplant Recipients
L. A. Coscia¹, A. Yusuf¹, S. Rao², S. Constantinescu³, M. J. Moritz⁴
¹Transplant Pregnancy Registry International, Philadelphia, PA, ²University of Virginia Heath System, Charlottesville, VA, ³Lewis Katz School of Medicine at Temple University, Philadelphia, PA, ⁴Surgery, Lehigh Valley Health Network, Allentown, PA
*Purpose: The purpose of this study was to describe 185 pregnancies in 108 heart transplant recipients.*Methods: Data regarding conceptions occurring between June 1987 and Dec…
2021 American Transplant Congress
Infection Rates in Heart Transplant Recipients With Combined Tacrolimus and Sirolimus at High versus Low Concentrations
S. Goyal, J. Lyons, J. Negrelli, M. Liebo, A. Heroux
Loyola University Medical Center, Maywood, IL
*Purpose: Assess the impact of tacrolimus-sirolimus (TAC/SRL) concentration on infection rate in heart transplant recipients (HTR).*Methods: A retrospective review of HTR on TAC/SRL for ≥…
2021 American Transplant Congress
The Pathology of Heart Allograft Biopsies: Discrepancies in Interpretation Between Conventional Histology and the Molecular Microscope Diagnostic (MMDx®) System
P. Randhawa¹, A. Seitz², Y. Huang¹, B. Feingold²
¹Department of Pathology, Pittsburgh, PA, ²Pediatrics, University of Pittsburgh, Pittsburgh, PA
*Purpose: There is growing interest in using transcriptomics to complement histologic evaluation of allograft hearts. The present study scrutinizes discrepancies between histologic and MMDx® systems…
2021 American Transplant Congress
Polyomavirus BK-Associated Nephropathy in Patients After Renal and Extrarenal Transplantation
A. Schwarz¹, J. Schmitz², J. Braesen², C. Bara³, M. Sauer⁴, H. Haller¹, J. Gottlieb⁵
¹Nephrology Department, Hannover Medical School, Hannover, Germany, ²Institute of Pathology, Hannover Medical School, Hannover, Germany, ³Department of Thoracic Surgery, Hannover Medical School, Hannover, Germany, ⁴Department of Pediatric Hematology, Hannover Medical School, Hannover, Germany, ⁵Deparment of Pneumology, Hannover Medical School, Hannover, Germany
*Purpose: Patients with non-renal organ transplantation (TX) may suffer BK-viral nephropathy (BKVN) of their own orthotopic kidneys. We aimed to know if these patients with…
2021 American Transplant Congress
Impact of Statin Intensity on the Incidence of Vascular Events and Graft Survival in Heart Transplant Recipients
E. Kim¹, I. Booth², R. Madathil³, B. Ravichandran¹, M. Demehin², M. Plazak²
¹University of Maryland School of Pharmacy, Baltimore, MD, ²Pharmacy, University of Maryland Medical Center, Baltimore, MD, ³University of Maryland School of Medicine, Baltimore, MD
*Purpose: Cardiac allograft vasculopathy (CAV) limits long-term graft survival of heart transplant (HT) recipients. In addition to decreased synthesis of cholesterol, statins also demonstrate immunomodulatory…
2021 American Transplant Congress
Improving Well-being for Heart Transplant Recipients: Implementation of a Patient Navigator Program
K. Ramonas, K. Ramonas
Health Navigator Foundation, San Francisco, CA
*Purpose: When surveyed, heart transplant recipients cited managing all their healthcare needs as a primary concern 83% of the time (n=23). To respond to this…
2021 American Transplant Congress
Assessing the Impact of Acute Major Adverse Kidney Events on Clinical Outcomes in Heart Transplant Recipients
J. E. Kelly¹, C. Perez¹, D. Taber¹, R. J. Tedford², B. McMahon², S. Alzaidi¹, H. B. Meadows¹
¹Pharmacy, MUSC Health, Charleston, SC, ²Medicine, MUSC Health, Charleston, SC
*Purpose: The purpose of this study was to elucidate contributors to the Major Adverse Kidney Events at 30 days (MAKE-30) outcome in heart transplant recipients…
2020 American Transplant Congress
Distribution of High-Urgency Listing and Regional Variation before and after Implementation of the 2018 US Heart Allocation Policy
T. Cascino¹, M. Skeans², V. Patel¹, M. Colvin¹
¹University of Michigan, Ann Arbor, MI, ²SRTR, Minneapolis, MN
*Purpose: The demand for heart transplant exceeds organ availability. The Organ Procurement and Transplantation Network/United Network for Organ Sharing (OPTN/UNOS) updated heart allocation policy in…

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