Articles tagged "Heart transplant patients"

2022 American Transplant Congress
An Updated Estimate of Post-Transplant Survival After Implementation of the New Donor Heart Allocation Policy
K. A. Lazenby¹, N. Narang², K. M. Pelzer³, G. Ran¹, W. F. Parker³
¹Pritzker School of Medicine, University of Chicago, Chicago, IL, ²Advocate Heart Institute, Advocate Christ Medical Center, Chicago, IL, ³Department of Medicine, University of Chicago, Chicago, IL
*Purpose: Published estimates showing lower post-transplant survival after implementation of the new heart allocation policy may be biased downward due to incomplete follow-up on surviving…
2022 American Transplant Congress
Outcome of Heart Transplantation After Pseudomonas Left Ventricular Assist Device Infection
L. Thirunavukarasu Murugan¹, C. Koval², J. Banzon³
¹Infectious Disease, Cleveland Clinic, Cleveland, OH, ²Cleveland Clinic Foundation, Cleveland, OH, ³Cleveland Clinic, Cleveland, OH
*Purpose: Pseudomonas aeruginosa (PA) is the most common gram-negative bacteria to cause left ventricular assist device (LVAD) infection. Management is difficult given limited oral antibiotic…
2022 American Transplant Congress
Outcomes in Hepatitis C (HCV) Viremic Grafts to HCV Negative Recipients in Heart Transplantation: A Multicenter Study of Differing Treatment Strategies
K. Ryland¹, B. Aqel², D. Steidley², P. Patel¹, S. Pungpapong³
¹Mayo Clinic, Jacksonville, FL, ²Mayo Clinic, Phoenix, AZ, ³Mayo Clinic College of Medicine, Jacksonville, FL
*Purpose: Using HCV viremic grafts for heart transplantation (HT) improves donor supply and shortens wait times. However, treatment strategies are variable post-transplant. This study aims…
2022 American Transplant Congress
Ventricular Modeling Following Bariatric Surgery Decreases Need for Heart Transplantation
R. Choudhury¹, A. Rouhi², G. Hoeltzel³, Y. Bababekov¹, A. Suarez-Pierre⁴, A. Yule¹, N. Vigneshwar⁴, N. Williams⁵, K. Dumon², T. Nydam¹
¹Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, ³General Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, ⁴Cardiothoracic Surgery, University of Colorado Hospital, Aurora, CO, ⁵General Surgery, Hospital of the University of Pennsylvania, Aurora, CO
*Purpose: For obese patients with congestive heart failure (CHF), aggressive weight loss has been associated with ventricular remodeling. Many have suggested offering bariatric surgery for…
2022 American Transplant Congress
Using Wearable Technology to Assess Activity in Children After Heart Transplant
J. B. Edelson¹, D. Gandla², S. M. Paridon¹, J. W. Rossano¹, M. J. O'Connor¹, M. Lane-Fall², B. Keating²
¹Children's Hospital of Philadelphia, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA
*Purpose: Evaluating activity tolerance following heart transplant (HT) provides an objective marker of functional status, can guide cardiac rehabilitation, identifies those patients with increased cardiovascular…
2022 American Transplant Congress
Heart-Kidney Transplantation Appears to Be Acceptable for Patients Greater Than 65 Years of Age
T. Singer-Englar, M. Kittleson, J. Patel, N. Patel, S. Kim, D. Chang, E. Kransdorf, L. Czer, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Heart-kidney transplantation (HKTx) has been found to improve survival in patients with advanced kidney disease who undergo heart transplantation. It is not known whether…
2022 American Transplant Congress
Use of Pronase to Identify HLA Crossmatch Antibody Interference
N. Hendren¹, C. Lacelle¹, S. Carter¹, J. L. Grodin¹, E. Hardin², M. Farr³, S. Garg¹
¹UT Southwestern, Dallas, TX, ²University of Texas Southwestern Medical Center, Dallas, TX, ³University of Texas Southwestern, Dallas, TX
*Purpose: Solid organ transplant centers should maintain vigilance that antibody therapies can impact HLA crossmatch results.*Methods: N/A*Results: A 46-year-old man with Mayo stage IV cardiac…
2022 American Transplant Congress
Phenytoin To Expedite Sirolimus & Tacrolimus Elimination: A Case Report
A. Lemke, B. A. Boilson, R. Razonable, S. A. Bernard
Mayo Clinic, Rochester, MN
*Purpose: Sirolimus (SIR), a mammalian target of rapamycin inhibitor (mTORi), may be used with or without a calcineurin inhibitor after heart transplant (HT). The anti-proliferative…
2022 American Transplant Congress
The Trajectory of Donor-Derived Cell-Free DNA (dd-cfDNA) Complements the Baseline Measurements in Heart Transplant Surveillance for Rejection
P. Shah¹, R. Cheng², H. Eisen³, B. D. Lowes⁴, L. Lourenco Jenkins⁵, Y. Fu⁵, K. Qu⁵, J. Teuteberg⁶, E. DePasquale⁷
¹Inova Heart and Vascular Institute, Falls Church, VA, ²University of Washington Heart Institute, Seattle, WA, ³Pennsylvania State University, Hershey, PA, ⁴University of Nebraska Medical Center, Omaha, NE, ⁵CareDx, Brisbane, CA, ⁶Stanford University, Stanford, CA, ⁷University of Southern California, Los Angeles, CA
*Purpose: Changes in dd-cfDNA levels over time may identify patients with evolving alloimmune injury, providing complementary information to the donor fraction. We explored the dd-cfDNA…
2022 American Transplant Congress
Impact of Cytomegalovirus Infection on mRNA Expression Utilizing the Molecular Microscope in Heart Transplant Recipients
S. S. Patlolla, J. Van Zyl, K. Castro, S. Mckean, R. Patel, S. Carey, A. Alam, S. Hall
Cardiology, Baylor University Medical Center, Dallas, TX
*Purpose: Little is known about the effect of CMV infection on transplant messenger RNA expression utilizing the molecular microscope (MMDx) in the absence of acute…