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Articles tagged "Heart transplant patients"

  • 2015 American Transplant Congress

    Electronic Health Service to Improve Therapeutic Drug Monitoring of Immunosuppressants

    M. Barten,1 J. Garbade,2 I. Hausladen,2 F. Mohr.2

    1Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany; 2Cardiac Surgery, University Leipzig Heart Center, Leipzig, Germany.

    PurposeTherapeutic drug monitoring (TDM) of immunosuppressants is critical to avoid rejection or toxic side effects by under- or over-immunosuppression after heart transplantation (HTx). Hence, in…
  • 2015 American Transplant Congress

    Acute Kidney Injury and Outcome After Cardiac Transplantation

    G. Fortrie,1 O. Manintveld,2 K. Caliskan,2 M. Betjes.1

    1Internal Medicine, Div. of Nephrology, Erasmus Medical Center, Rotterdam, Netherlands; 2Cardiology, Erasmus Medical Center, Rotterdam, Netherlands.

    Background:Chronic kidney disease (CKD) is a frequently seen complication after cardiac transplantation and is partly explained by the prolonged use of calcineurin inhibitors. However, few…
  • 2015 American Transplant Congress

    Correlation of Longitudinal Gene-Expression Profiling Score to Cytomegalovirus Infection: Results from the Outcomes AlloMap® Registry

    M. Kanwar,1 J. Yee,2 G. Ewald,3 S. Murali,1 J. Teuteberg.4

    1Allegheny Singer Research Institute, Pittsburgh, PA; 2CareDx, Inc., Brisbane, CA; 3Washington University, St. Louis, MO; 4University of Pittsburgh Medical Center, Pittsburgh, PA.

    Purpose: Cytomegalovirus (CMV) infection has been implicated in the pathogenesis of allograft rejection, which is reflected by high gene-expression profiling (GEP) scores. In the IMAGE…
  • 2015 American Transplant Congress

    The Impact of Administrating Everolimus Before Cytomegalovirus Infection to Prevent CMV Recurrence in Heart Transplant Recipients

    M. Ishida, K. Toda, T. Nakamura, S. Miyagawa, Y. Yoshikawa, S. Fukushima, S. Saito, D. Yoshioka, K. Kubota, T. Ueno, T. Kuratani, Y. Sawa.

    Cardiovascular Surgery, Osaka University, Suita, Osaka, Japan.

    Purpose – Cytomegalovirus (CMV) infection is a major complication in heart transplant recipients. Recent trials indicate that the use of the mammalian target of rapamycin…
  • 2015 American Transplant Congress

    Clinical Use of Gene-Expression Profiling to Monitor for Rejection After Cardiac Transplantation – Which Patients and When?

    J. Teuteberg,1 M. Shullo,1 T. Wolf,2 P. Prasad,2 G. Ewald.3

    1University of Pittsburgh Medical Center, Pittsburgh, PA; 2CareDx, Inc., Brisbane, CA; 3Washington University, St. Louis, MO.

    Background: Gene-expression profiling (GEP), in place of endomyocardial biopsy, is increasing. GEP testing is intended for low-risk asymptomatic patients (pts); thus, the profile of pts…
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