2015 American Transplant Congress
Can Gene-Expression Profiling Score Help Explain the Adverse Clinical Outcomes Seen in Gender-Mismatched Heart Transplants?
Background: Gene-expression profiling (GEP) testing, in conjunction with clinical assessment, is an established laboratory test intended to aid in the identification of acute cellular rejection…2015 American Transplant Congress
Donor-Derived Cell-Free DNA Is Stable in Non-Rejecting Heart Transplant Recipients in the CARGO II Multicenter Trial
1CareDx, Inc, Brisbane, CA; 2Drexel University, University of Philadelphia, Philadelphia, PA.
Purpose: An elevated fraction of donor-derived cell-free DNA (dd-cfDNA) detected in the venous blood of recipients has been shown to be correlated to rejection of…2015 American Transplant Congress
Molecular Testing for Microcirculation Injury Enhances the Assessment of Antibody-Mediated Rejection in Human Cardiac Allograft Biopsies
BACKGROUND: Despite continuous attempts to refine diagnostic consensus, accurate assessment of Antibody-mediated rejection (AMR) is an ongoing unmet need. The microcirculation represents the primary target…2015 American Transplant Congress
Molecular Correlates of Endothelial mTOR Activation in Heart Transplants Recipients
Paris Transplant Group & ATAGC, Paris - Edmonton, France.
BackgroundThe detection of phosphorylated effectors of the mTOR pathway in endothelial cells has been associated with in allograft rejection in animal models. The aim of…2015 American Transplant Congress
Single-Center Analysis of Adult, Combined Heart-Liver Transplant (CHLT) Recipients
Background: Combined heart-liver transplantation (CHLT) is life-saving for patients with end-stage heart-liver diseases. This is a review of patients who underwent CHLT at a single-center.Methods:…
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