Articles tagged "Glutathione"

2022 American Transplant Congress
HDAC6 Inhibition Mediated Protection from Hepatic Ischemia Reperfusion is Associated with Preserved Glutathione Levels
C. OBrien¹, P. Hernandez¹, S. Concors², Z. Wang¹, G. Ge³, A. Kozikowski⁴, W. Hancock⁵, M. Levine²
¹Surgery, University of Pennsylvania, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Surgery, University of Pensylvania, Philadelphia, PA, ⁴College of Pharmacy, University of Illinois at Chicago, Chicago, IL, ⁵Childrens Hospital of Philadelphia, Philadelphia, PA
*Purpose: Liver Ischemia reperfusion injury (IRI) and Acetaminophen (APAP) toxicity are important causes of acute liver failure in the United States, that lack effective therapy.…
2020 American Transplant Congress
DAMPs and NLRP3 Inflammasome Response in Fatty Liver Grafts Preservation in Different Preservation Solutions
R. G. Bardallo¹, R. G. Teixeira-Silva², A. Panisello-Rosello³, E. Folch-Puy³, J. Rosello Catafau⁴, T. Carbonell⁵
¹Cell Biology, Physiology and Immunology, Faculty of Biology, University of Barcelona, Barcelona, Spain, ²Experimental Pathology, Instituto de Investigaciones Biomedicas de Barcelona, CSIC, Barcelona, Spain, ³Experimental Pathology, Instituto de Investigaciones Biomedicas de Barcelona, Barcelona, Spain, ⁴Experimental Pathology, Instituto de Investigaciones Biomédicas de Barcelona, CSIC, Barcelona, Spain, ⁵Cell Biology, Physiollogy and Immunology, Faculty of Biology, University of Barcelona, Barcelona, Spain
*Purpose: Preservation solutions (UW, HTK and IGL-1) are widely used in clinical liver transplantation. It is well known that the composition of the preservation solution…