2017 American Transplant Congress
Glucocorticoid Receptor – Relaxin Signaling in Liver Transplant Ischemia-Reperfusion Injury (IRI): From Bench-to-Bedside.
Background: Glucocorticoid receptor (GR) serves as a receptor for relaxin (RLX), a pregnancy hormone, with novel vasoactive and tissue remodeling properties. A phase III clinical…2017 American Transplant Congress
Kidney-Specific Immunosuppression without Adverse Systemic Effects.
Purpose: Immunosuppressive therapy is often accompanied by severe adverse effects. To overcome this, the aim of this study was the evaluation of a kidney-specific drug…2017 American Transplant Congress
Dexamethasone Prolongs Cardiac Allograft Survival in a Murine Model Through Myeloid-Derived Suppressor Cells.
Recently, myeloid-derived suppressor cells (MDSCs) have attracted considerable attention because of their cancer-promoting and immunosuppressive effects. The glucocorticoid (GC) dexamethasone (Dex) is an important immunosuppressive…2017 American Transplant Congress
Avascular Necrosis in Kidney Transplant Recipients: Recent Data from a Cohort Study.
Avascular osteonecrosis (AVN) is the most disabling bone complication after kidney transplantation (KT). Its incidence decreased from 15% to 4% after the introduction of cyclosporine…2017 American Transplant Congress
Outcomes Following Solitary Pancreas Transplantation – Do Steroids Matter?
University of Illinois Hospital, Chicago
Background: Corticosteroids remain the cornerstone of maintenance immunosuppression following pancreas transplantation but are associated with significant short- and long-term complications. Data regarding steroid sparing regimens…2017 American Transplant Congress
Recurrence of IgA Nephropathy After Kidney Transplantation in Maintenance Steroids versus Steroid Avoidance Regimens: A UNOS/OPTN Analysis.
Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA
Background: There has been an increase in the use of steroid-avoidance regimens. However, there is some evidence to suggest that steroid avoidance may be associated…2016 American Transplant Congress
Clinical Factors That Determine the Appropriateness of Early Steroid Withdrawal.
Early steroid withdrawal (ESW) has been a popular option for recipients with low-immunological risk. However, no quantitative tools are available to assess the risk, i.e.…2016 American Transplant Congress
Comparison of Efficacy of Different Regimens for Treating Recurrent IgA Nephropathy After Kidney Transplantation.
Background Recurrent IgA nephropathy is a common complication after kidney transplantation. How to treat recipients with recurrent IgA nephropathy is still controversial. There are two…2015 American Transplant Congress
Human Leukocyte Antigen Mismatch and Steroid Maintenace in Kidney Transplantation
Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA.
Kidney transplant recipients (KTRs) with zero/minimal HLA mismatches against their donors enjoy superior long term outcomes related to diminished immune response of the recipient against…2015 American Transplant Congress
The Use of a Nurse Practitioner Led Transitional Diabetes Clinic Following Transplantation
Endocrinology Department, University Health Network - Toronto General Hospital, Toronto, ON, Canada.
The incidence of new onset diabetes after transplant [NODAT] ranges from 2% to 53%, also Type1 [T1DM] and Type 2 [T2DM] diabetes are common in…
American Transplant Congress abstracts