- 2017 American Transplant Congress - Avascular Necrosis in Kidney Transplant Recipients: Recent Data from a Cohort Study.Avascular osteonecrosis (AVN) is the most disabling bone complication after kidney transplantation (KT). Its incidence decreased from 15% to 4% after the introduction of cyclosporine…
- 2017 American Transplant Congress - Outcomes Following Solitary Pancreas Transplantation – Do Steroids Matter?- University of Illinois Hospital, Chicago Background: Corticosteroids remain the cornerstone of maintenance immunosuppression following pancreas transplantation but are associated with significant short- and long-term complications. Data regarding steroid sparing regimens…
- 2017 American Transplant Congress - Recurrence of IgA Nephropathy After Kidney Transplantation in Maintenance Steroids versus Steroid Avoidance Regimens: A UNOS/OPTN Analysis.- Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA Background: There has been an increase in the use of steroid-avoidance regimens. However, there is some evidence to suggest that steroid avoidance may be associated…
- 2017 American Transplant Congress - Glucocorticoid Receptor – Relaxin Signaling in Liver Transplant Ischemia-Reperfusion Injury (IRI): From Bench-to-Bedside.Background: Glucocorticoid receptor (GR) serves as a receptor for relaxin (RLX), a pregnancy hormone, with novel vasoactive and tissue remodeling properties. A phase III clinical…
- 2017 American Transplant Congress - Kidney-Specific Immunosuppression without Adverse Systemic Effects.Purpose: Immunosuppressive therapy is often accompanied by severe adverse effects. To overcome this, the aim of this study was the evaluation of a kidney-specific drug…
- 2017 American Transplant Congress - Dexamethasone Prolongs Cardiac Allograft Survival in a Murine Model Through Myeloid-Derived Suppressor Cells.Recently, myeloid-derived suppressor cells (MDSCs) have attracted considerable attention because of their cancer-promoting and immunosuppressive effects. The glucocorticoid (GC) dexamethasone (Dex) is an important immunosuppressive…
- 2016 American Transplant Congress - Clinical Factors That Determine the Appropriateness of Early Steroid Withdrawal.Early steroid withdrawal (ESW) has been a popular option for recipients with low-immunological risk. However, no quantitative tools are available to assess the risk, i.e.…
- 2016 American Transplant Congress - Comparison of Efficacy of Different Regimens for Treating Recurrent IgA Nephropathy After Kidney Transplantation.Background Recurrent IgA nephropathy is a common complication after kidney transplantation. How to treat recipients with recurrent IgA nephropathy is still controversial. There are two…
- 2015 American Transplant Congress - Human Leukocyte Antigen Mismatch and Steroid Maintenace in Kidney Transplantation- Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA. Kidney transplant recipients (KTRs) with zero/minimal HLA mismatches against their donors enjoy superior long term outcomes related to diminished immune response of the recipient against…
- 2015 American Transplant Congress - The Use of a Nurse Practitioner Led Transitional Diabetes Clinic Following Transplantation- Endocrinology Department, University Health Network - Toronto General Hospital, Toronto, ON, Canada. The incidence of new onset diabetes after transplant [NODAT] ranges from 2% to 53%, also Type1 [T1DM] and Type 2 [T2DM] diabetes are common in…
