2015 American Transplant Congress
1-Year Safety and Efficacy of Eculizumab in Adult aHUS Patients, With or Without a History of Renal Transplant
Background: Atypical hemolytic-uremic syndrome (aHUS) is a life-threatening, chronic disease of complement-mediated TMA. In aHUS, renal transplantation is associated with post-transplant (TP) TMA and ∼50–70%…2015 American Transplant Congress
Hypothermic Machine Perfusion Improves Kidney Viability through Amelioration of Vasospasm and Edema of Podocytes and Renal Tubular Epithelial Cells
Hypothermic machine perfusion (MP) may improve outcome after transplantation from donors after cardiac death (DCD) kidneys, but protective mechanisms of MP remain largely unknown. To…2015 American Transplant Congress
Acute Kidney Injury in the Early Post Kidney Transplant Period: Frequency, Etiology and Significance
Acute kidney injury (AKI) post kidney transplant has not been well described using current diagnostic criteria. The frequency and etiology of AKI in the first…2015 American Transplant Congress
Age-Dependent Decline in Glomerular Filtration Rate: A US Population-Based Study
Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA.
Background and aim: Reduced renal function is nearly a universal complication experienced by organ transplant recipients, in part related to nephrotoxicity of calcineurin inhibitors. With…2015 American Transplant Congress
NK-Cell Subset Distribution, Renal Function and Biopsy Findings in Kidney Transplant Recipients With HLA Donor-Specific Antibodies
Background: Detection of post-transplant donor-specific anti-HLA antibodies(DSA) constitutes a risk factor for kidney transplant (KT) loss. NK-cell antibody-dependent cell mediated cytotoxicity(ADCC) has been proposed to…2015 American Transplant Congress
Longitudinal eGFR Modelling to Understand Rates of eGFR Decline in Renal Transplantation in the United Kingdom
Background: The rate of decline in eGFR (slope) has been independently associated with a higher risk of cardiovascular events and all cause mortality in kidney…2015 American Transplant Congress
Acute Kidney Injury and Outcome After Cardiac Transplantation
Background:Chronic kidney disease (CKD) is a frequently seen complication after cardiac transplantation and is partly explained by the prolonged use of calcineurin inhibitors. However, few…2015 American Transplant Congress
MDRD4 Equation Is Better Than CKD-EPI, Cockroft-Gault and Nankivell Equations to Estimate Glomerular Filtration Rate in Renal Transplantation
To evaluate which estimated GFR (eGFR) equation is the most appropriate to in kidney transplanted (KTx) recipients, we obtained data from all plasma EDTA-Cr51 clearances…2015 American Transplant Congress
100 Protocol Renal Allograft Biopsies at 10 Years: First Look at the Tacrolimus Era
This study examined late renal allograft injury in the Tacrolimus era in 10-yr protocol biopsies (Bx).Methods One hundred 10-yr protocol allograft bx were assessed using…2015 American Transplant Congress
Interstitial Fibrosis Is the Critical Determinant of Impaired Renal Function in Transplant Glomerulopathy
PURPOSE: Transplant glomerulopathy (TGP) represents chronic antibody-mediated injury in the glomerular capillaries after renal transplantation, and is the main cause of graft failure. TGP is…
American Transplant Congress abstracts