2018 American Transplant Congress
Tacrolimus and Isavuconazole Therapy: What about the Drug Interaction?
1Henry Ford Hospital, Detroit; 2Wayne State University, Detroit, MI.
Introduction:Isavuconazole (ISV) is a triazole antifungal that is often utilized in solid organ transplant recipients (SOTR) for the treatment of invasive aspergillosis and mucormycosis. Isavuconazole…2018 American Transplant Congress
Defective Innate Immune Response to Opportunistic Pathogens in Cytomegalovirus-Infected Monocytes
Human cytomegalovirus (CMV) is the most common infection encountered in transplantation and is an important cause of morbidity and mortality in both solid organ and…2018 American Transplant Congress
Therapeutic Drug Monitoring (TDM) of Suspension (SUS), Extended-Release (ER), and Intravenous (IV) Posaconazole (POS) at a Large Transplant Center
Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA.
Background: Data on ER and IV POS among organ transplant recipients (OTRs) are limited, and the role of TDM is unclear.Methods: Retrospective study of patients…2018 American Transplant Congress
A Multi-Center Analysis of Risk Factors for Pneumocystis Pneumonia (PCP) in Solid Organ Transplant Recipients
Medicine, London Health Sciences Centre (LHSC), London, ON, Canada.
Introduction: Pneumocystis pneumonia (PCP) is associated with morbidity and mortality in solid organ transplant patients (SOTs). There are increasing reports of late PCP in SOT…2018 American Transplant Congress
Risk Factors for Invasive Fungal Infections among Lung Transplant Recipients
University of Pennsylvania, Philadelphia, PA.
Objective: Lung transplant (LT) recipients are at high risk of invasive fungal infections (IFI) with an estimated 1-year incidence of 8%. Despite advances in antifungal…2018 American Transplant Congress
Pneumocystis jiroveci Pneumonia (PJP) in Kidney and Pancreas Transplant Recipients in the Present Era of Routine Post-Transplant Prophylaxis: Risk Factors and Outcomes
University of Wisconsin, Madison.
PJP after transplant (TX) is associated with substantial morbidity and mortality. In the present era of universal and routine implementation of PJP prophylaxis (PPX) during…2017 American Transplant Congress
Diagnostic Bronchoscopy in Kidney Transplant Recipients with Acute Respiratory Failure: Risk or Value?
Nephrology, Charité Universitaetsmedizin, Berlin, Germany
Introduction:Few data evaluates the differential diagnostic value of bronchoalveolar lavages (FO-BAL) in kidney transplant recipients (KTR) with acute respiratory failure (ARF). We describe the results…2017 American Transplant Congress
Outcomes Following Reduction of Immunosuppression in Solid Organ Transplant Recipients with Cryptococcosis.
Background: Cryptococcosis (crypto) is the third most common fungal infection in solid organ transplant (SOT) recipients. Although reduction of immunosuppression (IS) may improve patient outcomes…2017 American Transplant Congress
MicroRNAs and Long Non-Coding RNAs as Potential Novel Biomarkers in Transplanted Patients with Candida Infection.
There is an urgent need to develop sensitive and specific biomarkers for the early diagnosis of candida infection in transplanted patients. miRNAs and lncRNAs are…2017 American Transplant Congress
Incidence of Fungal and Viral Infections Following Rituximab Use in Kidney Transplant Recipients.
Northwestern Memorial Hospital, Chicago, IL
Rituximab is used off-label in solid organ transplant for desensitization and treatment of antibody-mediated rejection (AMR). It targets CD20 and results in B cell depletion.…
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