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Articles tagged "Fungal infection"

  • 2018 American Transplant Congress

    Solid Organ Transplantation and Data Mining: Risk Factors for Invasive Fungal Disease in Heart Transplant Recipients

    N. Barros, D. Xie, C. Yek, T. Liu, X. Li, B. Adams-Huet, J. Martinez, S. Garg, J. Grodin, R. Morelend, A. Amin, F. Aras, J. Thibodeau, P. Mammen, M. Peltz, M. Drazner, W. Ring, R. Haley, R. La Hoz.

    UT Southwestern, Dallas, TX.

    We created a database of solid organ transplant (SOT) recipients using innovative data mining tools. This study describing the epidemiology of invasive fungal disease (IFD)…
  • 2018 American Transplant Congress

    Isavuconazole – The Real-World Use Experience

    H. Hassouna, V. Athans, K. Brizendine.

    Cleveland Clinic Foundation, Cleveland, OH.

    Isavuconazole (ISV) is a new triazole approved for treatment of mucormycosis and aspergillosis. Data on its effectiveness outside clinical trials and in patients receiving prior…
  • 2018 American Transplant Congress

    A Retrospective Review of De Novo Coccidioidomycosis among Remote Solid Organ Transplant Recipients in Arizona

    T. Zangeneh,1 J. August,1 N. Beatty,1 K. Asbury,2 L. Mi,2 J. Blair.2

    1Medicine/Division of Infectious Diseases, University of Arizona/Banner University Medical Center/Valley Fever Center for Excellence, Tucson, AZ; 2Medicine/Division of Infectious Diseases, Mayo Clinic Hospital, Phoenix, AZ.

    Background: Solid organ transplant (SOT) recipients residing in a Coccidioides-endemic region that acquire infection are at risk for complicated and protracted infection. Following transplantation, prophylaxis…
  • 2018 American Transplant Congress

    Outcomes of Renal Transplants from Donors with Positive Blood or Urine Cultures

    L. Chen,1 D. Kamiyama,2 L. Francalacci,1 E. Zhu,2 M. Donnelley,2 N. Clayton,2 K. Alman,1 A. De Mattos,1 J. Brown.3

    1Transplant Nephrology, UC Davis Medical Center, Sacramento, CA; 2Pharmacy, UC Davis Medical Center, Sacramento, CA; 3Infectious Diseases, UC Davis Medical Center, Sacramento, CA.

    OBJECTIVES: To evaluate outcomes in renal transplant recipients who received organs from donors with positive blood or urine cultures.METHODS: We performed a retrospective, single-center study…
  • 2018 American Transplant Congress

    Tacrolimus and Isavuconazole Therapy: What about the Drug Interaction?

    C. Gill,1 N. Mercuro,1 R. Kenney,1 A. Jantz,1 B. Summers,1 N. Sulejmani,1 S. Davis.1,2

    1Henry Ford Hospital, Detroit; 2Wayne State University, Detroit, MI.

    Introduction:Isavuconazole (ISV) is a triazole antifungal that is often utilized in solid organ transplant recipients (SOTR) for the treatment of invasive aspergillosis and mucormycosis. Isavuconazole…
  • 2018 American Transplant Congress

    Defective Innate Immune Response to Opportunistic Pathogens in Cytomegalovirus-Infected Monocytes

    P. Sen, A. R. Wilkie, R. Fernandes, R. J. Lane, S. E. Hickman, T. K. Means, E. R. Rosenberg, D. M. Coen, J. A. Fishman, J. El Khoury.

    Transplant and Immunocompromised Group, Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA; Department of Biological Chemistry and Pharmacology, Harvard Medical School, Boston, MA.

    Human cytomegalovirus (CMV) is the most common infection encountered in transplantation and is an important cause of morbidity and mortality in both solid organ and…
  • 2017 American Transplant Congress

    Clinical Risk Factors for Bronchiolitis Obliterans Syndrome (BOS) in Lung Transplant Recipients (LTRs): Results of an International Cohort Study.

    N. Law,1 B. Hamandi,1 C. Fegbeutel,2 F. Silveira,3 E. Verschuuren,4 P. Ussetti,5 P. Chin-Hong,6 A. Solé,7 C.-L. Holmes-Liew,8 E. Billaud,9 P. Grossi,10 O. Manuel,11 D. Levine,12 R. Barbers,13 D. Hadjiliadis,14 L. Singer,1 S. Husain.1

    1University Health Network, Toronto, ON, Canada; 2Hannover Medical School, Hannover, Germany; 3University of Pittsburgh, Pittsburgh, PA; 4University Medical Center Groningen, University of Groningen, Groningen, Netherlands; 5Hospital Puerta de Hierro, Madrid, Spain; 6University of California, San Francisco, CA; 7University and Polytechnic Hospital La Fe, Universidad de Valencia, Valencia, Spain; 8Royal Adelaide Hospital, Adelaide, Australia; 9APHP Hopital Européen G Pompidou, Paris, France; 10University of Insubria, Varese, Italy; 11University Hospital of Lausanne, Lausanne, Switzerland; 12University of Texas Health Science Center San Antonio, San Antonio, TX; 13KECK Medical Center of University of Southern California, Los Angeles, CA; 14University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, PA

    Introduction:Bronchiolitis obliterates syndrome (BOS) is a major impediment in the long term survival of LTRs. The main objective of this study was to identify infectious…
  • 2017 American Transplant Congress

    High Mortality in Transplant Recipients Associated with Coccidioidomycosis Derived from Organ Donors.

    N. Jeyakumar,2 N. Neidlinger,3 M. Salvatore,3 C. Brown,4 T. Carpenter,3 M. Fung,1 P. Chin-Hong.1

    1Department of Medicine, University of California, San Francisco, San Francisco, CA; 2Department of Medicine, University of Miami Miller School of Medicine, Miami, FL; 3Donor Network West, San Ramon, CA; 4Decision Patterns, Oakland, CA

    Purpose Coccidioidomycosis (CI) occurs in 4-9% of solid organ recipients in endemic areas, resulting in 30-63% mortality. CI can be transmitted directly via transplantation, but…
  • 2017 American Transplant Congress

    The Feared Five Fungal Infections in Kidney Transplant Recipients: 20-Year Experience at a Midwestern Center.

    S. Parajuli, A. Wick, S. Pandeya, B. Astor, J. Smith, A. Djamali, D. Mandelbrot.

    University of Wisconsin, Madison, WI

    Invasive fungal infections (IFI) are increasing in kidney transplant recipients (KTR). Here we present our experience with five feared IFIs in KTR transplanted between 01/01/1994…
  • 2017 American Transplant Congress

    Diagnostic Bronchoscopy in Kidney Transplant Recipients with Acute Respiratory Failure: Risk or Value?

    D. Khadzhynov, J. Deissler, F. Halleck, L. Lehner, K. Budde, O. Staeck.

    Nephrology, Charité Universitaetsmedizin, Berlin, Germany

    Introduction:Few data evaluates the differential diagnostic value of bronchoalveolar lavages (FO-BAL) in kidney transplant recipients (KTR) with acute respiratory failure (ARF). We describe the results…
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