2018 American Transplant Congress
Increase in Potentially Resistant Non-Aspergillus Molds Isolated in Lung Transplant Recipients after Voriconazole and Posaconazole Prophylaxis
Background: Lung transplant recipients are at higher risk for invasive fungal infections compared to other solid organs transplant patients. Antifungal prophylaxis with mold-active azoles has…2018 American Transplant Congress
Micafungin Prophylaxis in Liver Transplant Recipients at High Risk for Invasive Fungal Infections
Medstar Georgetown University Hospital, Department of Pharmacy, Washington, DC.
Purpose: This study was conducted to determine the incidence of proven or probable invasive fungal infections in the first 90 days after transplant in high…2018 American Transplant Congress
Solid Organ Transplantation and Data Mining: Risk Factors for Invasive Fungal Disease in Heart Transplant Recipients
We created a database of solid organ transplant (SOT) recipients using innovative data mining tools. This study describing the epidemiology of invasive fungal disease (IFD)…2018 American Transplant Congress
Isavuconazole – The Real-World Use Experience
Cleveland Clinic Foundation, Cleveland, OH.
Isavuconazole (ISV) is a new triazole approved for treatment of mucormycosis and aspergillosis. Data on its effectiveness outside clinical trials and in patients receiving prior…2018 American Transplant Congress
A Retrospective Review of De Novo Coccidioidomycosis among Remote Solid Organ Transplant Recipients in Arizona
Background: Solid organ transplant (SOT) recipients residing in a Coccidioides-endemic region that acquire infection are at risk for complicated and protracted infection. Following transplantation, prophylaxis…2018 American Transplant Congress
Outcomes of Renal Transplants from Donors with Positive Blood or Urine Cultures
OBJECTIVES: To evaluate outcomes in renal transplant recipients who received organs from donors with positive blood or urine cultures.METHODS: We performed a retrospective, single-center study…2018 American Transplant Congress
Tacrolimus and Isavuconazole Therapy: What about the Drug Interaction?
1Henry Ford Hospital, Detroit; 2Wayne State University, Detroit, MI.
Introduction:Isavuconazole (ISV) is a triazole antifungal that is often utilized in solid organ transplant recipients (SOTR) for the treatment of invasive aspergillosis and mucormycosis. Isavuconazole…2018 American Transplant Congress
Defective Innate Immune Response to Opportunistic Pathogens in Cytomegalovirus-Infected Monocytes
Human cytomegalovirus (CMV) is the most common infection encountered in transplantation and is an important cause of morbidity and mortality in both solid organ and…2018 American Transplant Congress
Therapeutic Drug Monitoring (TDM) of Suspension (SUS), Extended-Release (ER), and Intravenous (IV) Posaconazole (POS) at a Large Transplant Center
Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA.
Background: Data on ER and IV POS among organ transplant recipients (OTRs) are limited, and the role of TDM is unclear.Methods: Retrospective study of patients…2018 American Transplant Congress
A Multi-Center Analysis of Risk Factors for Pneumocystis Pneumonia (PCP) in Solid Organ Transplant Recipients
Medicine, London Health Sciences Centre (LHSC), London, ON, Canada.
Introduction: Pneumocystis pneumonia (PCP) is associated with morbidity and mortality in solid organ transplant patients (SOTs). There are increasing reports of late PCP in SOT…
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