ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "FK506"

  • 2015 American Transplant Congress

    Comparison of Renal Outcomes for Liver Transplant Recipients With Pretransplant Renal Dysfunction Receiving Sirolimus Or Tacrolimus With Rabbit Antithymocyte Globulin Induction

    B. Duhart,1 W. Ally,2 V. Rao,3 A. Krauss,4 J. Eason,3 J. Vanatta.3

    1University of Tennessee College of Pharmacy, Memphis, TN; 2Pharmacy, University of Virginia Medical Center, Charlottesville, VA; 3Surgery, Methodist University Hospital Transplant Institute/University of Tennessee Health Science Center, Memphis, TN; 4Pharmacy, Methodist University Hospital, Memphis, TN.

    Published data are limited describing renal outcomes in orthotopic liver transplant (OLT) recipients prescribed de novo sirolimus (SRL) maintenance immunosuppression and rabbit antithymocyte globulin (rATG).…
  • 2015 American Transplant Congress

    Effects of Immunosuppressives On Porcine Renal Microvascular Endothelial Cell–Activated Human T Cell Proliferation: A Cellular Model of Kidney Xenotransplantation In Vitro

    Z.-Y. Wang, M. Tector, S. Nagai, J. Butler, R. Blankenship, S. Downey, J. Estrada, P. Li, A. Tector.

    Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Background: The creation of genetically-modified pigs has brought us closer than ever to clinical xenotransplantation. However, the optimal immunosuppressive doses still need to be established…
  • 2015 American Transplant Congress

    Single Cell Phospho-Protein Analysis Demonstrates That Immunosuppressive Drugs Inhibit MAPK and mTOR Signaling Molecules in Primary Monocytes After Transplantation

    N. Kannegieter, D. Hesselink, R. Kraaijeveld, G. de Graav, M. Betjes, W. Weimar, C. Baan.

    Nephrology and Transplantation, Dept. of Internal Medicine, Erasmus MC, Rotterdam, Netherlands.

    Monocytes have been identified as key players driving rejection processes. It is therefore surprising that there are almost no data available about the impact of…
  • 2015 American Transplant Congress

    Biomarker for Calcineurin Inhibitors Nephrotoxicity in Solid Organ Transplantation: Validation of a Urine Gene Expression Panel

    D. Maluf, R. Gehrau, J. Suh, K. Brayman, C. Bustamante, M. Edmunds, P. Darvishi, V. Mas.

    UVA, Charlottesville, VA.

    Background: We previously described a gene expression signature as biomarker of calcineurin inhibitor nephrotoxicity (CNIT) post renal transplantation. Herein, we aimed to validate the same…
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