ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Epstein-Barr virus (EBV)"

  • 2016 American Transplant Congress

    Targeting the Constitutively Active PI3K/Akt/mTOR Signaling Pathway in Epstein-Barr Virus B Cell Lymphomas.

    A. Sang, G. Ivison, C. Esquivel, S. Krams, O. Martinez.

    Division of Abdominal Transplantation, Stanford School of Medicine, Stanford, CA.

    Epstein-Barr virus (EBV) B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD) is a major problem in organ transplantation. Reduction of immunosuppression sometimes result in tumor…
  • 2016 American Transplant Congress

    Monocytic TNF-α Response to EBV Peptides as a Mean to Identify Over-Immunosuppressed Kidney Transplant Recipients.

    P. Vallin,1 O. Désy,1 S. Béland,1 E. Wagner,2 S. De Serres.1

    1Renal Division, Quebec University Health Center, Laval University, Quebec, QC, Canada; 2Immunology and Histocompatibility Laboratory, Quebec University Health Center, Laval University, Quebec, QC, Canada.

    Background. The reduction in acute rejection rates seen with the current triple immunosuppressive maintenance regimen has come at the expense of an increased risk of…
  • 2016 American Transplant Congress

    Chronic High Epstein-Barr Viral Load Carriage in Pediatric Kidney Transplant Recipients.

    M. Yamada,1 P. Fadaker,1 C. Nguyen,1 A. Ganoza,2 A. Humar,2 M. Michaels,1,2 M. Green.1,2

    1Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, PA; 2Surgery, University of Pittsburgh, Pittsburgh, PA.

    BackgroundThe development of Epstein-Barr virus (EBV) infection and post-transplant lymphoproliferative disorder (PTLD) is normally associated with a high EBV viral load in peripheral blood. Observations…
  • 2016 American Transplant Congress

    Rare Presentation of PTLD as Parotitis.

    R. Pullalarevu, A. Posadas Salas, G. Mour, T. Srinivas, N. Salazar, P. Mohan.

    Medicine, MUSC, Charleston, SC.

    28y/o AAF w/ hx of CAH, HTN, and ESRD, was on HD for 3 yrs. Pt was EBV seronegative prior to transplant (tx). She received…
  • 2015 American Transplant Congress

    Clinical and Virologic Outcomes in High-Risk Adult EBV D+/R- Organ Transplant Recipients

    D. Kumar, N. Patil, S. Husain, C. Chaparro, A. Humar.

    UHN, Toronto, Canada.

    Background:EBV D+/R- organ transplant recipients are a high risk group for developing PTLD. This subgroup of patients has been primarily evaluated in pediatric populations with…
  • 2015 American Transplant Congress

    Epstein Barr Virus Modulates Host Cell MicroRNA-194 to Promote IL-10 Production in B Cell Lymphomas

    A. Harris-Arnold, S. Schaffert, O. Hatton, C. Esquivel, S. Krams, O. Martinez.

    Surgery/Division of Abdominal Transplant, Stanford University School of Medicine, Stanford, CA.

    Epstein Barr virus (EBV) infection is associated with the development of post-transplant lymphoproliferative disorder (PTLD) which can manifest as aggressive B cell lymphomas in transplant…
  • 2015 American Transplant Congress

    Post-Transplant Lymphoproliferative Disorders Following Alemtuzumab Induction in Kidney Transplantation

    H. Sawhney, R. Charif, J. Galliford, A. Mclean, D. Taube.

    Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, England, United Kingdom.

    Post-Transplant Lymphoproliferative Disorder (PLTD) is a well-recognised serious complication in renal transplant recipients. Induction with lymphocyte depleting agents such as thymoglobulin has been associated with…
  • 2015 American Transplant Congress

    B Cell MicroRNA as Biomarkers for Epstein-Barr Virus Associated Post-Transplant Lymphoproliferative Disorder

    A. Harris-Arnold, V. Kaul, S. Shaffert, O. Hatton, C. Esquivel, S. Krams, O. Martinez.

    Surgery/Division of Abdominal Transplant, Stanford University School of Medicine, Stanford, CA.

    Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of organ transplantation and is commonly associated with Epstein Barr virus (EBV) infection. EBV viral loads…
  • 2015 American Transplant Congress

    Genetic Diversity Epstein-Barr Virus Latent Gene EBNA-1 Among Transplant Patients and Patients With Infectious Mononucleosis

    K. Sullivan,1 S. Isabel,1 E. Maria,1 P. Tara,1 Y. Simon,1 K. Nasser,1 N. Vicky,2 A. Upton.1

    1Department of Infections Diseases, Hospital for Sick Children, Toronto, ON, Canada; 2Transplant Centre, Hospital for Sick Children, Toronto, ON, Canada.

    Introduction:-The distribution of Epstein Barr Virus (EBV)-associated pathologies varies worldwide. It is associated with the majority of cases of post-transplant lymphoproliferative disorder (PTLD). The EBNA-1…
  • 2015 American Transplant Congress

    Preemptive Rituximab Therapy of Epstein-Barr Virus (EBV) Infection to Prevent Post-Transplant Lymphoproliferative Disease (PTLD) After Pediatric Solid Organ Transplantation (SOT)

    Y. Ahn,1 N.-J. Yi,2 S. Min,2 I.-S. Ha,1 H. Cheong,1 H. Kang.1

    1Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea; 2Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.

    Purpose: More than 90% of pediatric PTLD after solid organ transplantation is associated with EBV infection. Reduction in immunosuppression is the first step to prevent…
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