2017 American Transplant Congress
Lymphoproliferative Disorders After Renal Transplantation Along Two Decades: A Large Longitudinal Study.
In a longuitudinal study,we evaluated the cumulative incidence of Posttransplant limphoproliferative disorders(PTLD),its relationship with Epstein Barr Virus (EBV),classical risk factors and outcome in 21546 single…2017 American Transplant Congress
BK Virus, Cytomegalovirus and Epstein-Barr Virus Reactivation in Renal Transplant Patients: Results from a Large Multicenter Study.
The purpose of this study was to ascertain the prevalence and clinical implications of three of the most relevant opportunistic infections in kidney transplantation, namely…2017 American Transplant Congress
Risk Factors for Post-Transplant Lymphoproliferative Disorders in Epstein-Barr Virus Mismatch Lung Transplant Recipients.
Brigham and Women's Hospital, Boston
Background: Post-transplant lymphoproliferative disorders (PTLD) are associated with significant morbidity and morality. Lung transplant patients appear to have higher rates of PTLD than other solid…2017 American Transplant Congress
EBV-Specific CD8+ T Cells from Pediatric Thoracic vs Abdominal Transplant Recipients Are Shaped Differently by the Chronic EBV Loads with Potential Impact on the Risk of PTLD.
Background: EBV infection and post-transplant lymphoproliferative disorders (PTLD) are life-threatening complications of pediatric solid organ transplantation (Tx). Chronic high EBV viral load (HVL) carriers have…2017 American Transplant Congress
The miRNome of EBV+ PTLD is Distinct from EBV+ Infectious Mononucleosis.
Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of organ transplantation commonly associated with Epstein Barr virus (EBV) infection. More than 90% of the…2017 American Transplant Congress
Genomic Diversity of Epstein-Barr Virus in Post-Transplant Lymphoproliferative Disorder.
Program in Immunology, Stanford University School of Medicine, Stanford, CA
Purpose: In transplant recipients, Epstein-Barr Virus (EBV) is associated with the development of B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD). We used next-generation sequencing…2017 American Transplant Congress
Presence of Anellovirus Nucleic Acid Sequences in Involved Tissue Is Associated with Worse Patient Survival in Post-Transplant Lymphoproliferative Disorder.
Washington University in St Louis School of Medicine, St. Louis
Introduction: PTLD remain a feared complication of organ and tissue transplant, with high morbidity and mortality. While 50-80% of cases are strongly associated with Epstein-Barr…2017 American Transplant Congress
Rituximab Desensitization (DES) and Alemtuzumab Induction Significantly Reduced EBV Viremia and Post-Transplant Lymphoproliferative Disorder (PTLD) in HLA-Sensitized (HS) Kidney Transplant Patients.
Background: PTLD is a serious complication in KTx pts and is usually associated with EBV infection. Recent studies showed that rituximab treatment prior to Tx…2017 American Transplant Congress
Risk of Primary Central Nervous System Lymphoma in Solid Organ Transplant Recipients.
National Cancer Institute, Bethesda, MD
Background: Risk of primary central nervous system lymphoma (PCNSL) is greatly increased in immunosuppressed HIV-infected people. Case series describe PCNSL in solid organ transplant (SOT)…2017 American Transplant Congress
Does EBV Viremia at Time of Transplant Have a Negative Impact on Transplant Outcomes?
University of Minnesota, Minneapolis
Being EBV antibody (Ab) positive at the time of transplant increases the risk of post-transplant lymphoproliferative disorder (PTLD) and is a significant threat to patient…
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