ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Epstein-Barr virus (EBV)"

  • 2018 American Transplant Congress

    Peptides Encoded by EBV Latent Cycle Proteins Affect NK Cell Reactivity

    B. Mbiribindi, C. Romero Moreno, C. Esquivel, O. Martinez, S. Krams.

    Department of Surgery, Stanford University School of Medicine, Stanford, CA.

    Introduction: Epstein–Barr virus (EBV) infects more than 90% of adults worldwide and is associated with several malignancies, including post-transplant lymphoproliferative disorder (PTLD). Although EBV infection…
  • 2018 American Transplant Congress

    Do We Need to Worry about EBV DNAemia in the Late Post-Transplant Period?

    M. Morton,1 K. Daga,2 P. Klapper,2 M. Picton,1 P. Vallely.2

    1Department of Renal Medicine, Manchester Royal Infirmary, Manchester, United Kingdom; 2University of Manchester, Manchester, United Kingdom.

    Background: Despite detectable Epstein-Barr virus (EBV) in blood, kidney transplant patients (KTR) may have no apparent clinical consequence. This study aims to explore the clinical…
  • 2018 American Transplant Congress

    Lymphocyte Proportions Post Thymectomy Are Associated with Allergic Disorders in Heart Transplanted Children

    T. Kim,1 L. Ionescu,1,2,3 N. Avdimiretz,4 M. Larsen,1,2,3 F. Murdoch,1,2 B. Motyka,1,2,3 S. Gilmour,1,2 L. West,1,2,3 S. Urschel.1,2,3

    1Pediatrics, University of Alberta, Edmonton, AB, Canada; 2Stollery Children's Hospital, Edmonton, AB, Canada; 3Alberta Transplant Institute, Edmonton, Canada; 4The Hospital for Sick Children, Toronto, Canada.

    Background: Allergic disorders are more common in pediatric heart transplant (HTx) recipients than non-transplanted children, with young age at HTx and thymectomy being risk factors.…
  • 2018 American Transplant Congress

    Decreased Post Heart Transplant Survival with Epstein-Barr Virus Mismatch in the Current Era

    M. Kittleson, J. Patel, E. Kransdorf, S. Dimbil, R. Levine, S. Mersola, D. Geft, D. Chang, L. Czer, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: Epstein-Barr virus (EBV) has been implicated in a multitude of cancers, including B-cell lymphoma, Burkitt's lymphoma, CNS lymphoma, gastric cancer and nasopharyngeal carcinoma. Previous…
  • 2018 American Transplant Congress

    Survival, Cancer and PTLD Diagnosis after Late EBV Infection in Adult Kidney Transplantation

    M. Morton,1 G. Scullin,2 K. Daga,2 P. Klapper,2 P. Vallely,2 M. Picton.1

    1Department of Renal Medicine, Manchester Royal Infirmary, Manchester, United Kingdom; 2Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, United Kingdom.

    Introduction: While EBV seronegative recipients have a high risk of early PTLD knowledge is lacking regarding the implications of EBV DNAemia in stable patients in…
  • 2018 American Transplant Congress

    Follow-Up and Outcomes of Epstein-Barr Virus Negative Recipients after a Kidney Transplant from an Epstein-Barr Virus Positive Donor

    C. Dudreuilh, E. Asgari, R. Hilton.

    Departments of Nephrology and Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

    Introduction: Post-transplant lymphoproliferative disorder (PTLD) is one of the most serious complications of chronic immunosuppression after an organ transplant. One of the major risk factors…
  • 2018 American Transplant Congress

    Use of Cyclin-Dependent Kinase Inhibitors to Reduce Gammaherpesvirus Reactivation

    J. Hazleton,1 L. van Dyk.2

    1Pediatrics, Division of Infectious Diseases, University of Colorado School of Medicine, Aurora, CO; 2Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO.

    Infection with the gammaherpesvirus EBV occurs in over 90% of humans and leads to lifelong viral latency with intermittent reactivation that is typically controlled through…
  • 2018 American Transplant Congress

    Presentation and Outcomes of Post-Transplant Proliferative Disorder at a Single Institution Pediatric Transplant Center

    G. Ramos-Gonzalez,1 A. Allain,1 T. Agur,1 L. O'Melia,1 S. Staffa,2 S. Burchett,1 B. Siegele,3 O. Weinberg,3 N. Rodig,1 R. Fawaz,1 T. Singh,1 D. Freiberger,1 K. Heung Bae.1

    1Pediatric Transplant Center, Boston Children's Hospital, Boston, MA; 2Department of Surgery, Boston Children's Hospital, Boston, MA; 3Department of Pathology, Boston Children's Hospital, Boston, MA.

    Purpose: The aim of this study was to characterize features present at the time of post-transplant lymphoproliferative disorder (PTLD) diagnosis, as well as outcomes, following…
  • 2018 American Transplant Congress

    Post-Transplant Lymphoproliferative Disorder after Kidney Transplantation: A Single Institute Experience with Focus on Epstein-Barr Virus Status

    P. Zhang,1 R. King,1 K. Ristow,2 L. Cornell,1 F. Cosio,3 T. Habermann,2 M. Alexander.1

    1Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN; 2Divsion of Hematology and Oncology, Mayo Clinic, Rochester, MN; 3Divsion of Nephrology and Hypertension, Mayo Clinic, Rochester, MN.

    Background: Comparing to other types of solid organ transplant, the Post-Transplant Lymphopro- liferative Disorder (PTLD) in kidney transplant recipients (KTRs) is relatively rare. Due to…
  • 2018 American Transplant Congress

    Multi-Visceral Transplant in an HIV Positive Recipient – One Year Survival

    S. Nagaraju, R. Mangus, J. Fridell.

    Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Human immunodeficiency virus (HIV) is associated with hypercoagulability and thrombotic events. Highly active anti-retroviral therapy (HAART) has improved long term survival. More patients with HIV…
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