ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Epstein-Barr virus (EBV)"

  • 2018 American Transplant Congress

    Survival, Cancer and PTLD Diagnosis after Late EBV Infection in Adult Kidney Transplantation

    M. Morton,1 G. Scullin,2 K. Daga,2 P. Klapper,2 P. Vallely,2 M. Picton.1

    1Department of Renal Medicine, Manchester Royal Infirmary, Manchester, United Kingdom; 2Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, United Kingdom.

    Introduction: While EBV seronegative recipients have a high risk of early PTLD knowledge is lacking regarding the implications of EBV DNAemia in stable patients in…
  • 2018 American Transplant Congress

    Follow-Up and Outcomes of Epstein-Barr Virus Negative Recipients after a Kidney Transplant from an Epstein-Barr Virus Positive Donor

    C. Dudreuilh, E. Asgari, R. Hilton.

    Departments of Nephrology and Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

    Introduction: Post-transplant lymphoproliferative disorder (PTLD) is one of the most serious complications of chronic immunosuppression after an organ transplant. One of the major risk factors…
  • 2018 American Transplant Congress

    Use of Cyclin-Dependent Kinase Inhibitors to Reduce Gammaherpesvirus Reactivation

    J. Hazleton,1 L. van Dyk.2

    1Pediatrics, Division of Infectious Diseases, University of Colorado School of Medicine, Aurora, CO; 2Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO.

    Infection with the gammaherpesvirus EBV occurs in over 90% of humans and leads to lifelong viral latency with intermittent reactivation that is typically controlled through…
  • 2018 American Transplant Congress

    Presentation and Outcomes of Post-Transplant Proliferative Disorder at a Single Institution Pediatric Transplant Center

    G. Ramos-Gonzalez,1 A. Allain,1 T. Agur,1 L. O'Melia,1 S. Staffa,2 S. Burchett,1 B. Siegele,3 O. Weinberg,3 N. Rodig,1 R. Fawaz,1 T. Singh,1 D. Freiberger,1 K. Heung Bae.1

    1Pediatric Transplant Center, Boston Children's Hospital, Boston, MA; 2Department of Surgery, Boston Children's Hospital, Boston, MA; 3Department of Pathology, Boston Children's Hospital, Boston, MA.

    Purpose: The aim of this study was to characterize features present at the time of post-transplant lymphoproliferative disorder (PTLD) diagnosis, as well as outcomes, following…
  • 2018 American Transplant Congress

    Post-Transplant Lymphoproliferative Disorder after Kidney Transplantation: A Single Institute Experience with Focus on Epstein-Barr Virus Status

    P. Zhang,1 R. King,1 K. Ristow,2 L. Cornell,1 F. Cosio,3 T. Habermann,2 M. Alexander.1

    1Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN; 2Divsion of Hematology and Oncology, Mayo Clinic, Rochester, MN; 3Divsion of Nephrology and Hypertension, Mayo Clinic, Rochester, MN.

    Background: Comparing to other types of solid organ transplant, the Post-Transplant Lymphopro- liferative Disorder (PTLD) in kidney transplant recipients (KTRs) is relatively rare. Due to…
  • 2018 American Transplant Congress

    Multi-Visceral Transplant in an HIV Positive Recipient – One Year Survival

    S. Nagaraju, R. Mangus, J. Fridell.

    Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Human immunodeficiency virus (HIV) is associated with hypercoagulability and thrombotic events. Highly active anti-retroviral therapy (HAART) has improved long term survival. More patients with HIV…
  • 2018 American Transplant Congress

    Val-Ganciclovir Prophylaxis Delays Onset of EBV Viremia in the First Year Post-Solid Organ Transplantation in High-Risk Patients

    S. Albatati,1 A. Sharma,2 S. Gantt,1 K. Haubrich,1 A. Wright,1 T. Blydt-Hansen.1

    1University of British Columbia, Vancouver, Canada; 2University of Manitoba, Winnipeg, Canada.

    Introduction: Donor-derived primary Epstein-Barr virus (EBV) infection poses serious risks to EBV naïve children post-solid organ transplantation, including development of EBV-related PTLD. Currently, there is…
  • 2018 American Transplant Congress

    Cancer Incidence after Kidney Transplantation in Saudi Arabia, Comparing Different Induction Agents

    H. AlEid, S. Raza, T. Ali, I. Alahmadi, S. Aleid, D. Broering.

    Kidney and Pancreas Transplantation, King Faisal Specialist Hospital, Riyadh, Saudi Arabia.

    Cancer incidence varies among different induction agents and different population. We aim to compare the incidence of cancer post kidney transplantation among different induction agents…
  • 2018 American Transplant Congress

    Genomic Diversity of Epstein Barr Virus in Post-Transplant Lymphoproliferative Disorder

    E. Maloney,1 V. Busque,2 S. Hui,2 S. Krams,1,2 C. Esquivel,1,2 O. Martinez.1,2

    1Stanford Immunology, Stanford University School of Medicine, Stanford, CA; 2Department of Surgery/Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA.

    Purpose: In transplant recipients, Epstein-Barr Virus (EBV) is associated with the development of B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD). We utilized next-generation sequencing…
  • 2018 American Transplant Congress

    Prospective Analysis of EBV+ PTLD Incidence in Pediatric Transplant Recipients in the Modern Era

    O. Martinez,1 S. Krams,1 M. Lapasaran,1 S. Boyd,2 D. Bernstein,2 C. Twist,3 K. Weinberg,2 D. Gratzinger,2 B. Tan,2 B. Armstrong,4 D. Ikle,4 M. Brown,5 M. Robien,5 C. Esquivel,1 The CTOTC-06 Investigators.

    1Surgery/Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford; 2Stanford University School of Medicine, Stanford; 3Roswell Park, Buffalo; 4Rho, Chapel Hill; 5NIAID/NIH, Bethesda.

    Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. The Clinical Trials of Organ Transplantation in Children (CTOTC)-06 is an NIAID-sponsored…
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