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American Transplant Congress abstracts

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Articles tagged "Epstein-Barr virus (EBV)"

  • 2018 American Transplant Congress

    Post-Transplant Lymphoproliferative Disorder after Kidney Transplantation: A Single Institute Experience with Focus on Epstein-Barr Virus Status

    P. Zhang,1 R. King,1 K. Ristow,2 L. Cornell,1 F. Cosio,3 T. Habermann,2 M. Alexander.1

    1Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN; 2Divsion of Hematology and Oncology, Mayo Clinic, Rochester, MN; 3Divsion of Nephrology and Hypertension, Mayo Clinic, Rochester, MN.

    Background: Comparing to other types of solid organ transplant, the Post-Transplant Lymphopro- liferative Disorder (PTLD) in kidney transplant recipients (KTRs) is relatively rare. Due to…
  • 2018 American Transplant Congress

    Multi-Visceral Transplant in an HIV Positive Recipient – One Year Survival

    S. Nagaraju, R. Mangus, J. Fridell.

    Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Human immunodeficiency virus (HIV) is associated with hypercoagulability and thrombotic events. Highly active anti-retroviral therapy (HAART) has improved long term survival. More patients with HIV…
  • 2018 American Transplant Congress

    Val-Ganciclovir Prophylaxis Delays Onset of EBV Viremia in the First Year Post-Solid Organ Transplantation in High-Risk Patients

    S. Albatati,1 A. Sharma,2 S. Gantt,1 K. Haubrich,1 A. Wright,1 T. Blydt-Hansen.1

    1University of British Columbia, Vancouver, Canada; 2University of Manitoba, Winnipeg, Canada.

    Introduction: Donor-derived primary Epstein-Barr virus (EBV) infection poses serious risks to EBV naïve children post-solid organ transplantation, including development of EBV-related PTLD. Currently, there is…
  • 2018 American Transplant Congress

    Cancer Incidence after Kidney Transplantation in Saudi Arabia, Comparing Different Induction Agents

    H. AlEid, S. Raza, T. Ali, I. Alahmadi, S. Aleid, D. Broering.

    Kidney and Pancreas Transplantation, King Faisal Specialist Hospital, Riyadh, Saudi Arabia.

    Cancer incidence varies among different induction agents and different population. We aim to compare the incidence of cancer post kidney transplantation among different induction agents…
  • 2018 American Transplant Congress

    Genomic Diversity of Epstein Barr Virus in Post-Transplant Lymphoproliferative Disorder

    E. Maloney,1 V. Busque,2 S. Hui,2 S. Krams,1,2 C. Esquivel,1,2 O. Martinez.1,2

    1Stanford Immunology, Stanford University School of Medicine, Stanford, CA; 2Department of Surgery/Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA.

    Purpose: In transplant recipients, Epstein-Barr Virus (EBV) is associated with the development of B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD). We utilized next-generation sequencing…
  • 2018 American Transplant Congress

    Prospective Analysis of EBV+ PTLD Incidence in Pediatric Transplant Recipients in the Modern Era

    O. Martinez,1 S. Krams,1 M. Lapasaran,1 S. Boyd,2 D. Bernstein,2 C. Twist,3 K. Weinberg,2 D. Gratzinger,2 B. Tan,2 B. Armstrong,4 D. Ikle,4 M. Brown,5 M. Robien,5 C. Esquivel,1 The CTOTC-06 Investigators.

    1Surgery/Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford; 2Stanford University School of Medicine, Stanford; 3Roswell Park, Buffalo; 4Rho, Chapel Hill; 5NIAID/NIH, Bethesda.

    Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. The Clinical Trials of Organ Transplantation in Children (CTOTC)-06 is an NIAID-sponsored…
  • 2018 American Transplant Congress

    Detection of Different Gene Expression Profiles in CD8+ T Cells from Chronic High EBV Load Carriers after Pediatric Heart and Liver Transplantation

    M. Yamada,1,2 C. Macedo,2 X. Gu,2 M. Michaels,1,2 M. Green,1,2 C. Nguyen,1,2 U. Chandran,3 B. Feingold,1,2 G. Mazariegos,1,2 D. Metes.1,2

    1Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Thomas E. Starzl Transplantation Institute, Pittsburgh, PA; 3Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA.

    Background: EBV infection and post-transplant lymphoproliferative disorders (PTLD) are life-threatening complications of pediatric solid organ transplantation (Tx). The risk for PTLD varies by transplanted organ,…
  • 2018 American Transplant Congress

    Viral-Specific Cytotoxic T-Cell (Viral-Tc) Responses in Highly-HLA-Sensitized Patients (HS) Maintained on Tacrolimus and Everolimus Post-HLAi Kidney Transplant

    S. Ge,1 M. Chu,1 A. Karasyov,1 D. Lovato,1 J. Kahwaji,2 A. Vo,1 J. Choi,1 S. Louie,1 S. Jordan,1 M. Toyoda.1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; 2Kidney Transplantation, Kaiser Permanente Medical Center, Los Angeles, CA.

    Introduction: Viral infections represent significant infectious complications post- kidney transplant which may be increased with desensitization. CMV, EBV and BKV infections are the most prevalent.…
  • 2018 American Transplant Congress

    Peptides Encoded by EBV Latent Cycle Proteins Affect NK Cell Reactivity

    B. Mbiribindi, C. Romero Moreno, C. Esquivel, O. Martinez, S. Krams.

    Department of Surgery, Stanford University School of Medicine, Stanford, CA.

    Introduction: Epstein–Barr virus (EBV) infects more than 90% of adults worldwide and is associated with several malignancies, including post-transplant lymphoproliferative disorder (PTLD). Although EBV infection…
  • 2018 American Transplant Congress

    Do We Need to Worry about EBV DNAemia in the Late Post-Transplant Period?

    M. Morton,1 K. Daga,2 P. Klapper,2 M. Picton,1 P. Vallely.2

    1Department of Renal Medicine, Manchester Royal Infirmary, Manchester, United Kingdom; 2University of Manchester, Manchester, United Kingdom.

    Background: Despite detectable Epstein-Barr virus (EBV) in blood, kidney transplant patients (KTR) may have no apparent clinical consequence. This study aims to explore the clinical…
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