ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Epstein-Barr virus (EBV)"

  • 2019 American Transplant Congress

    Epstein Barr Virus DNA Integration in B Cell Lymphomas of Post-Transplant Lymphoproliferative Disorder

    M. C. McPherson, O. M. Martinez

    Surgery, Division of Abdominal Transplant, Stanford University School of Medicine, Stanford, CA

    *Purpose: Epstein Barr virus-positive (EBV+) B cell lymphomas can arise in immunosuppressed individuals, such as organ transplant recipients in the context of post-transplant lymphoproliferative disorder…
  • 2019 American Transplant Congress

    Genomic Variations in Epstein Barr Virus are Associated with Post-Transplant Lymphoproliferative Disorder

    M. Arvedson, E. Maloney, C. Esquivel, O. Martinez, S. Krams

    Stanford Univ School of Med, Stanford, CA

    *Purpose: Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of organ transplantation characterized by abnormal proliferation of lymphoid cells in the setting of immunosuppression.…
  • 2019 American Transplant Congress

    Post-Transplant Lymphoproliferative Disorders after Living-Donor Liver Transplantation: A Retrospective Cohort Study in 1,900 Cases of Single Center Experience

    T. Tajima1, K. Hata1, H. Haga2, M. Nishikori3, J. Kusakabe1, I. Tamaki1, T. Ito1, T. Kaido1, A. Takaori-Kondo3, S. Uemoto1

    1Div. of HBP Surgery and Transplantation, Dept. of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2Dept. of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan, 3Dept. of Hematology and Oncology, Kyoto University Graduate School of Medicine, Kyoto, Japan

    *Purpose: Post-transplant lymphoproliferative disorders (PTLD) is relatively rare but the most common, life-threatening neoplasms after organ transplantation. Because of their heterogeneity from benign to malignant…
  • 2019 American Transplant Congress

    Post-transplant Lymphoproliferative Disorder Following Intestine Transplantation: Contemporary Single Center Experience

    A. Zimmerman, J. Hawksworth, A. Kroemer, P. Radkani, K. Khan, S. Kaufman, N. Yazigi, S. Subramanian, T. Fishbein, C. Matsumoto

    Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC

    *Purpose: The purpose of this study was to examine the characteristics and risk factors for PTLD after intestinal transplant.*Methods: Retrospective review of intestinal transplant recipients…
  • 2018 American Transplant Congress

    Val-Ganciclovir Prophylaxis Delays Onset of EBV Viremia in the First Year Post-Solid Organ Transplantation in High-Risk Patients

    S. Albatati,1 A. Sharma,2 S. Gantt,1 K. Haubrich,1 A. Wright,1 T. Blydt-Hansen.1

    1University of British Columbia, Vancouver, Canada; 2University of Manitoba, Winnipeg, Canada.

    Introduction: Donor-derived primary Epstein-Barr virus (EBV) infection poses serious risks to EBV naïve children post-solid organ transplantation, including development of EBV-related PTLD. Currently, there is…
  • 2018 American Transplant Congress

    Cancer Incidence after Kidney Transplantation in Saudi Arabia, Comparing Different Induction Agents

    H. AlEid, S. Raza, T. Ali, I. Alahmadi, S. Aleid, D. Broering.

    Kidney and Pancreas Transplantation, King Faisal Specialist Hospital, Riyadh, Saudi Arabia.

    Cancer incidence varies among different induction agents and different population. We aim to compare the incidence of cancer post kidney transplantation among different induction agents…
  • 2018 American Transplant Congress

    Genomic Diversity of Epstein Barr Virus in Post-Transplant Lymphoproliferative Disorder

    E. Maloney,1 V. Busque,2 S. Hui,2 S. Krams,1,2 C. Esquivel,1,2 O. Martinez.1,2

    1Stanford Immunology, Stanford University School of Medicine, Stanford, CA; 2Department of Surgery/Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA.

    Purpose: In transplant recipients, Epstein-Barr Virus (EBV) is associated with the development of B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD). We utilized next-generation sequencing…
  • 2018 American Transplant Congress

    Prospective Analysis of EBV+ PTLD Incidence in Pediatric Transplant Recipients in the Modern Era

    O. Martinez,1 S. Krams,1 M. Lapasaran,1 S. Boyd,2 D. Bernstein,2 C. Twist,3 K. Weinberg,2 D. Gratzinger,2 B. Tan,2 B. Armstrong,4 D. Ikle,4 M. Brown,5 M. Robien,5 C. Esquivel,1 The CTOTC-06 Investigators.

    1Surgery/Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford; 2Stanford University School of Medicine, Stanford; 3Roswell Park, Buffalo; 4Rho, Chapel Hill; 5NIAID/NIH, Bethesda.

    Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. The Clinical Trials of Organ Transplantation in Children (CTOTC)-06 is an NIAID-sponsored…
  • 2018 American Transplant Congress

    Detection of Different Gene Expression Profiles in CD8+ T Cells from Chronic High EBV Load Carriers after Pediatric Heart and Liver Transplantation

    M. Yamada,1,2 C. Macedo,2 X. Gu,2 M. Michaels,1,2 M. Green,1,2 C. Nguyen,1,2 U. Chandran,3 B. Feingold,1,2 G. Mazariegos,1,2 D. Metes.1,2

    1Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Thomas E. Starzl Transplantation Institute, Pittsburgh, PA; 3Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA.

    Background: EBV infection and post-transplant lymphoproliferative disorders (PTLD) are life-threatening complications of pediatric solid organ transplantation (Tx). The risk for PTLD varies by transplanted organ,…
  • 2018 American Transplant Congress

    Viral-Specific Cytotoxic T-Cell (Viral-Tc) Responses in Highly-HLA-Sensitized Patients (HS) Maintained on Tacrolimus and Everolimus Post-HLAi Kidney Transplant

    S. Ge,1 M. Chu,1 A. Karasyov,1 D. Lovato,1 J. Kahwaji,2 A. Vo,1 J. Choi,1 S. Louie,1 S. Jordan,1 M. Toyoda.1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; 2Kidney Transplantation, Kaiser Permanente Medical Center, Los Angeles, CA.

    Introduction: Viral infections represent significant infectious complications post- kidney transplant which may be increased with desensitization. CMV, EBV and BKV infections are the most prevalent.…
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