2020 American Transplant Congress
Epidemiology of EBV Infection and EBV Load Kinetics after Pediatric Living Donor Liver Transplantation
National Center for Child Health and Development, Tokyo, Japan
*Purpose: Epstein-Barr virus (EBV) is a ubiquitous virus that infects more than 90% of adult population worldwide. EBV infection after pediatric liver transplantation (LT) accounts…2020 American Transplant Congress
Transplant Monitoring and PTLD Detection with B Cell Receptor Repertoire Analysis in a Large Prospective Pediatric Cohort
*Purpose: Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. The Clinical Trials of Organ Transplantation in Children (CTOT-C)-06 is a…2020 American Transplant Congress
Patterns of Belatacept Use and Risk of Post-Transplant Lymphoproliferative Disorder (PTLD) in US Kidney Transplant Recipients – Analysis of Organ Procurement and Transplantation Network (OPTN) Database
1United Network for Organ Sharing (UNOS), Richmond, VA, 2Bristol-Myers Squibb, Princeton, NJ
*Purpose: Belatacept, a selective T-cell costimulation blocker, was approved in 2011 for the prophylaxis of organ rejection in Epstein-Barr virus (EBV)-seropositive kidney transplant recipients. PTLD…2020 American Transplant Congress
Long-Term Outcomes of Patients with Epstein-barr Virus-Driven Post-Transplant Lymphoproliferative Disease Following Solid Organ Transplant or Allogeneic Hematopoietic Cell Transplant Treated with Tabelecleucel in an Expanded Access Program Study
*Purpose: There is a need for effective, well‑tolerated therapies in pts who develop Epstein-Barr virus-driven post-transplant lymphoproliferative disease (EBV+ PTLD) after solid organ (SOT) or…2020 American Transplant Congress
Genome-Wide Analysis of Epstein Barr Virus Identifies Variations in the Latency Gene EBNA3C That Are Associated with Post Transplant Lymphoproliferative Disorder
Stanford University Sch of Med, Stanford, CA
*Purpose: Epstein Barr virus (EBV) is a gamma herpes virus that is associated with a variety of human malignancies including EBV+ B cell lymphomas in…2020 American Transplant Congress
Role of CAR-T Cell Therapy in Post Transplant Lymphoproliferative Disorder
Transplant, Washington University in St. Louis, Saint Louis, MO
*Purpose: Chimeric Antigen Receptor (CAR) T cells are a genetically modified autologous immunotherapy that uses a patient’s own T cells modified with a chimeric antigen…2020 American Transplant Congress
Valganciclovir for Epstein-Barr Virus Prevention after Pediatric Kidney Transplant
1Intermountain Healthcare, Salt Lake City, UT, 2University of Utah, Salt Lake City, UT
*Purpose: Epstein-Barr virus (EBV) infection after pediatric kidney transplant (pKTx) is common and can lead to post transplant lymphoproliferative disorder (PTLD). Valganciclovir (VGN) is used…2020 American Transplant Congress
Vira-ome: A Tool for an Unbiased Plasma Virome Analysis of SOT Recipients from Cell-Free DNA Sequences
R&D, Viracor-Eurofins, Lee's Summit, MO
*Purpose: Blood virome of healthy individuals is frequently predominated by member of families such as Herpesvirus, Anellovirus and Polyomaviridae. The viral load of commensal species…2019 American Transplant Congress
Anti-ebv Antibody (ebv-ab) And Ebv-specific Cytotoxic T Cell (ebv-tc) Positivity Are Essential To Control Viremia In Seronegative (sero[-]) Pediatric Kidney Transplant Recipients (ped Ktx Pts).
Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: EBV infection represents a significant morbidity factor in KTx Pts, especially EBV sero(-) Ped as infections tend to be more severe and recurrent, increasing…2019 American Transplant Congress
Quantitative Epstein-Barr Virus Viral Load Monitoring in Pediatric Kidney Transplantation
*Purpose: Epstein Barr virus (EBV) belongs to the family of herpesvirus and is associated with a wide range of malignancies, including post-transplant lymphoproliferative disorder (PTLD).…
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