Articles tagged "Endothelin"

2021 American Transplant Congress
The Summarized Assessment of Endothelin a Receptors Expression in Renal Transplant Compartments is Associated with Antibody Mediated Rejection
M. Banasik¹, K. Nowanska¹, P. Donizy², K. Koscielska-Kasprzak³, S. Zmonarski¹, M. Kuriata-Kordek¹, A. Tukiendorf⁴, A. Hałoń², D. Janczak⁵, M. Krajewska¹
¹Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland, ²Department of Pathomorphology and Oncological Cytology, Wroclaw Medical University, Wroclaw, Poland, ³Research laboratory, Wroclaw Medical University, Wroclaw Medical University, Wroclaw, Poland, ⁴Department of Public Health, Wroclaw Medical University, Wroclaw, Poland, ⁵Department of General, Vascular and Transplant Surgery, Wroclaw Medical University, Wroclaw, Poland
*Purpose: The presence of non-HLA anti-endothelin A receptor antibodies may be important in transplant injury but the expression of the endothelin A receptor (ETA receptor)…
2020 American Transplant Congress
Non-HLA Antibodies in Severe Post-Operative Thrombotic Microangiopathy among Kidney Transplant Recipients
R. Bonakdar, P. Serrano Rodriguez
University of North Carolina Hospitals, Chapel Hill, NC
*Purpose: From August 2018 until July 2019, an alarming 6% of kidney transplant recipients at this transplant center had biopsy-proven thrombotic microangiopathy (TMA) within 1…
2018 American Transplant Congress
Human Atrial Natriuretic Peptide (hANP) in Cold Storage of Donation after Cardiac Death Livers: A New Tool for Protecting Vascular Endothelia?
Y. Nigmet,¹ K. Hata,¹ Y. Okamura,¹ I. Tamaki,¹ T. Tsuruyama,² H. Hirao,¹ T. Kubota,¹ J. Kusakabe,¹ J. Yoshikawa,¹ T. Goto,¹ T. Tajima,¹ H. Tanaka,¹ S. Uemoto.¹
¹Department of Surgery, Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University, Kyoto, Japan; ²Center for Anatomical, Pathological, and Forensic Medical Research, Kyoto University, Kyoto, Japan.
Aim: Current critical shortage of donor organs has led to acceptance of donation after cardiac death (DCD) livers for transplantation. Human atrial natriuretic peptide (hANP)…
2018 American Transplant Congress
Endothelin A Receptor (ETaR) siRNA Ameliorates Renal Ischemia Reperfusion Injury through Upregulating Expression of eNOS in Rats
Y. Jia, L. Li, T. Zhu.
Shanghai Key Labratory of Organ Transplantation, Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Aims: To explore the protective effect of Endothelin A Receptor (ETaR) siRNA on renal ischemia reperfusion injury and its underlying mechanism.Methods: The model of unilateral…
2016 American Transplant Congress
Preformed Antibodies Against AT₁R and EDNRA Correlate with Rejection Post-Transplant.
A. Gareau,¹ C. Wiebe,^1,2 D. Pochinco,² I. Gibson,³ D. Rush,¹ P. Nickerson.^1,2,4
¹Internal Medicine, University of Manitoba, Winnipeg, MB, Canada; ²Diagnostic Services of Manitoba, Winnipeg, MB, Canada; ³Pathology, University of Manitoba, Winnipeg, MB, Canada; ⁴Immunology, University of Manitoba, Winnipeg, MB, Canada.
Studies have investigated the potential pathogenic effects of non-HLA antibodies (Ab), with a few reporting that Ab against the angiotensin II type 1 receptor (AT1R)…