2021 American Transplant Congress
Novel Morphologic Biomarkers of Cardiac Allograft Remodeling are Associated with Multiple Peri- and Post-transplant Inflammatory Processes
*Purpose: It has long been recognized that transplanted hearts develop a stiffened, restrictive physiology at an accelerated rate compared to native hearts. While this is…2020 American Transplant Congress
Foxp3+ Innate and TGF-ß+ Adaptive Regulatory Immune Cells in Quilty Lesions are Associated with Acceptance of Heart Allograft
University of Texas Southwestern Medical Center, Dallas, TX
*Purpose: To evaluate the cellular composition of Quilty lesions in heart transplant biopsies and their association with acceptance or rejection of cardiac allografts.*Methods: This study…2019 American Transplant Congress
Reference Ranges Donor-Derived Cell-Free DNA in a Heart Transplant Population
1Saint Luke's, Kansas City, MO, 2CareDx, Brisbane, CA, 3University of Los Angeles, Los Angeles, CA
*Purpose: Elevations in donor-derived cell-free DNA (dd-cfDNA) ≥0.20 % in heart transplant recipients (HTR) has been shown to be associated with a probability of acute…2017 American Transplant Congress
Antibody Mediated Rejection and Donor Specific Antibodies in Heart Transplant Patients: Single Center Experience.
BACKGROUND AND AIMS: Preexisting donor specific antibodies (DSA) cause acute antibody mediated rejection (AMR), which can be avoided during pre-transplant work up. Diagnosis and management…2016 American Transplant Congress
Development and Validation of a Molecular Microscope Diagnostic System (MMDx) for Heart Transplant Biopsies.
The diagnosis of heart transplant rejection by histology in endomyocardial biopsies (EMB) is challenging. A molecular system (MMDx) has been developed to assess both T…2016 American Transplant Congress
Assessment of Molecular Mechanisms of Non-Transplant Cardiac Hypertrophy in Cardiac Allograft Hypertrophy – An Exploratory Gene Array Study of Myocardial Biopsy Samples.
Cardiac Allograft Hypertrophy (CAH) develops in up to 80% of patients as early as six months post-transplant, and is associated with decreased quality of life…2015 American Transplant Congress
Inverse Monocytic Subset Profile in Blood and Tissue During Heart Transplant Rejection
Introduction: Increased monocytic infiltration of heart transplant tissue is documented during acute rejection. It is still unclear how changes in circulating monocyte pool relate to…
American Transplant Congress abstracts