ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Donors"

  • 2018 American Transplant Congress

    Shared Genetic Ancestry as a Predictor of Medium Term Renal Transplant Outcome in Deceased Donor Transplants

    C. Stapleton,1 On behalf of the UK and Ireland Renal Transplant Consortium, P. Conlon,2 G. Cavalleri.1

    1Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland; 2Department of Nephrology, Beaumont Hospital, Dublin, Ireland.

    Sibling transplant pairs have better transplant outcomes than unrelated donor recipient (DR) pairs indicating that shared genetic ancestry between donors and recipients can aid in…
  • 2018 American Transplant Congress

    Ex Vivo Bloodless Oxygen Carrier for Perfusion of DCD Kidneys during Subnormothermic Storage

    P. Luke,1,2 M. Richard-Mohamed,2 A. Haig,3 R. Mayer,2 S. Aquil,2 A. Sener,2 A. Jevnikar,1,2 R. Bhattacharjee.1,2

    1Matthew Mailing Centre for Translational Transplant Studies, London, ON, Canada; 2Multi-Organ Transplant Program, London Health Sciences Centre, London, ON, Canada; 3Pathology and Laboratory Medicine, London Health Sciences Centre, London, ON, Canada.

    Background: Non-oxygenated static or machine perfusion in cold (4[deg]C) remains the gold standard in transplantation and an optimal method of oxygen delivery to ischemic kidneys…
  • 2018 American Transplant Congress

    Kidney and Liver DCD Outcomes – A Five Year Review

    J. Buggs,1 J. Boone,2 M. Adesunkanmi,2 R. Mehta,2 E. Rogers,3 A. Kumar,4 A. Alsina,1 V. Bowers.1

    1Transplant Surgery, Tampa General Medical Group, Tampa General Hospital, Tampa, FL; 2Pre-Med Undergraduate, University of South Florida, Tampa, FL; 3Transplant Research, Tampa General Hospital, Tampa, FL; 4Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL.

    Background: The demand for organ transplantation exceeds the supply and has led to an increase in use of donation after cardiac death (DCD) solid organs…
  • 2018 American Transplant Congress

    Livers from Diabetic Donors Can Safely Be Used in Donation after Circulatory Death Liver Transplantation

    I. Brüggenwirth,1 I. Vasiliauskaire,2 A. Westerkamp,1 W. Polak,2 A. Braat,3 R. Porte.1

    1Surgery, UMCG, Groningen, Netherlands; 2Surgery, Erasmus MC, Rotterdam, Netherlands; 3Surgery, LUMC, Leiden, Netherlands.

    Liver grafts from donors with a history of diabetes mellitus (DM) have been associated with reduced graft survival after liver transplantation. Transplantation centers are often…
  • 2018 American Transplant Congress

    Influence of Liver Allograft Steatosis on Postoperative Acute Kidney Injury

    C. Jadlowiec,1 S. Mao,2 D. Abdelwahab,1 A. Nehra,2 T. Taner.2

    1Mayo Clinic, Phoenix, AZ; 2Mayo Clinic, Rochester, MN.

    With the ongoing organ shortage, there has been an increased interest in using moderately steatotic liver allografts. The impact of such allografts on recipients' post-liver…
  • 2018 American Transplant Congress

    Trends in Liver Transplantation with Older Liver Donors in the United States

    C. Haugen, X. Luo, A. Thomas, C. Holscher, J. Garonzik-Wang, M. McAdams-DeMarco, D. Segev.

    Surgery, JHU, Baltimore.

    As the US population ages, older liver donors (OLDs) represent a potential expansion of the donor pool. Historically, grafts from OLDs have been associated with…
  • 2018 American Transplant Congress

    Impact of ELAD C3A Cell Conditioned Medium Enhanced Perfusate Fluid on Functional Recovery of Extended Criteria Donor Livers during Normothermic Machine Perfusion

    S. Afford,2 L. Wallace,2 R. Laing,2 Y. Botteon,2 D. He,3 S. Soundararajan,4 D. Mirza,1 R. Ashley,3 J. Brotherton,3 H. Mergental,1 D. Reich.4

    1Queen Elizabeth Hospital, Birmingham, United Kingdom; 2University of Birmingham, Birmingham, United Kingdom; 3Vital Therapies Inc, San Diego, CA; 4Drexel University, Philadelphia.

    Reconditioning of donor livers by Normothermic Machine Perfusion (NMP) is already increasing the numbers of transplantable organs from the extended criteria donors. The hepatoblastoma-derived cell…
  • 2018 American Transplant Congress

    Donor and Procedural Variability in DCD Liver Transplant: Is It Time to Come to a Consensus?

    L. Ruffolo, M. Balceniuk, R. Hernandez Alejandro.

    Department of Surgery, University of Rochester Medical Center on Behalf of the IDOL Consortium, Rochester, NY.

    Background:Donation after cardiocirculatory death liver transplantation (DCD LT) has re-emerged in part because of insufficient grafts for patients on waiting lists. Unfortunately, DCD LT has…
  • 2018 American Transplant Congress

    A Decade of Dual Kidney Transplantation Reveals Excellent Patient Outcomes from Otherwise Discarded Organs

    I. Rajput, S. Farid, A. Hakeem, M. Jameel, N. Ahmad, O. Masood.

    Department of Organ Transplantation, St. James's University Hospital, Leeds, United Kingdom.

    IntroductionBridging the disparity between the kidney waiting list and donor pool remains challenging. For highly sensitised patients and older recipients the wait is contributing to…
  • 2018 American Transplant Congress

    HLA Typing, Panel Reactive Antibody and Donor Specific Antigen Tests Are Not Necessary for Successful Parathyroid Allotransplantation

    E. Kanimdan,1 B. Goncu,2 Y. Gelmez,3 O. Idiz,4 C. Toka,5 B. Ozdemir,2 H. Basoglu,6 N. Ozten Kandas,7 E. Yucesan,8 Y. Ersoy,5 R. Kazancioglu,9 E. Aysen.5

    1Bezmialem Vakif University, Faculty of Medicine, Department of Medical Biology, Istanbul, Turkey; 2Bezmialem Vakif University, Experimental Research Center, Istanbul, Turkey; 3Istanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Immunology, Istanbul, Turkey; 4Istanbul Training and Research Hospital, Department of General Surgery, Istanbul, Turkey; 5Bezmialem Vakif University, Faculty of Medicine, Department of General Surgery, Istanbul, Turkey; 6Bezmialem Vakif University, Faculty of Medicine, Department of Biophysics, Istanbul, Turkey; 7Bezmialem Vakif University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Istanbul, Turkey; 8Bezmialem Vakif University, Institute of Life Sciences and Biotechnology, Istanbul, Turkey; 9Bezmialem Vakif University, Faculty of Medicine, Department of Internal Medicine, Istanbul, Turkey.

    Permanent hypoparathyroidism(PH) is incurable condition and requires life long drug therapy.Unique therapeutic option is parathyroid allotransplantation(PA).Some studies use routinely but emprically HLA typing,PRA(panel reactive antibody)…
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