Articles tagged "Donors"

2018 American Transplant Congress
Use of Hepatitis-C Treatments after Kidney Transplantation: Impact of the Direct-Acting Antiviral Era
K. Lentine, D. Axelrod,² R. Bloom,³ H. Xiao,¹ D. Segev,⁴ T. Alhamad,⁵ H. Randall,¹ R. Ouseph,¹ V. Dharnidharka,⁵ D. Brennan,⁴ N. Lam,⁶ A. Naik,⁷ G. Hess,⁸ B. Kaiske,⁹ M. Schnitzler.¹
¹Saint Louis U, St. Louis; ²Lahey, Burlington; ³U Penn, Philadelphia; ⁴Johns Hopkins, Baltimore; ⁵Washington U, St. Louis; ⁶U Alberta, Edmonton, Canada; ⁷U Michigan, Ann Arbor; ⁸Hennepin, Minneapolis; ⁹Symphony Health, Conshohocken.
Hepatitis C virus (HCV) infection in kidney transplant (KTx) donors or recipients has correlated with adverse outcomes, partly due to limited treatment options. Development of…
2018 American Transplant Congress
Livers from Donation after Circulatory Death Donors Can Be Safely Used for Retransplantation
O. van Leeuwen,¹ M. van Reeven,² J. Erdmann,³ H. Metselaar,⁴ A. van den Berg,⁵ B. van Hoek,⁶ W. Polak,² R. Porte.¹
¹Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; ²Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands; ³Department of Surgery, Leiden University Medical Center, Leiden, Netherlands; ⁴Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Netherlands; ⁵Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, Netherlands; ⁶Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands.
Introduction: After donation after circulatory death (DCD) liver transplantation (LT), non-anastomotic biliary strictures (NAS) and early allograft dysfunction (EAD) are more frequently observed than after…
2018 American Transplant Congress
Hard-To-Place Kidney Offers: System- Level Predictors of Discard
L. Kayler,¹ J. Nie,² K. Noyes,² M. Leeman,³ R. Narvaez.¹
¹Dept of Surgery, University at Buffalo, Buffalo, NY; ²Dept of Epidemiology and Environmental Health, University at Buffalo, Buffalo, NY; ³Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY.
Background: Deceased-donor kidney discard rates remain high. Inefficiencies in the allocation of hard-to-place kidneys may be contributing to discard suggesting that system-level factors represent opportunities…
2018 American Transplant Congress
Diffuse Optical Non-Invasive Organ Risk (DONOR) Indexing Using Diffuse Reflectance Spectroscopy for Pre-Transplant Evaluation
H. Borron,¹ D. Piao,² A. Hawxby,³ H. Wright,³ E. Rubin.⁴
¹College of Medicine, University of Oklahoma, Oklahoma City, OK; ²School of Electrical and Computer Engineering, Oklahoma State University, Stillwater, OK; ³Oklahoma Transplant Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK; ⁴Pathology, University of Oklahoma, Oklahoma City, OK.
Purpose: Due to large transplant waitlists, a rapid, non-invasive method to evaluate organ quality for transplantation is needed. Diffuse optical spectroscopy (DOSi) is an optical…
2018 American Transplant Congress
Comparison of Continuous Normothermic Ex Vivo Kidney Perfusion to Hypothermic Preservation Methods in Pig Kidneys Donated after Cardiac Death
M. Hamar,^1,2 P. Urbanellis,¹ D. Kollmann,¹ I. Linares,¹ M. Kaths,¹ D. Bagli,³ A. Konvalinka,⁴ I. Mucsi,¹ A. Ghanekar,¹ L. Robinson,² M. Selzner.¹
¹Multi Organ Transplant Program, TGH, Toronto, ON, Canada; ²Division of Nephrology, The Hospital of Sick Children, Toronto, ON, Canada; ³Dept. of Surgery (Urology) & Physiology, The Hospital of Sick Children, Toronto, ON, Canada; ⁴Dept. of Medicine and Institute of Medical Science, UHN and Univ. of Toronto, Toronto, ON, Canada.
Background: Strategies to decrease preservation-related injury in renal grafts donated after circulatory death urgently needed. This highlights the importance of direct comparison of dynamic preservation…
2018 American Transplant Congress
Effect of Kidney Allocation System on a Solitary, Isolated, Rural Transplant Program
K. Brown,² S. Hill,² L. Lipscomb,² A. Jones,² J. Africa.¹
¹Glickman Institute, Cleveland Clinic, Cleveland, OH; ²Urology and Renal Transplant, Charleston Area Medical Center, Charleston, WV.
The new kidney allocation system (KAS) was expected to create an impact on smaller, rural and geographically isolated centers.Methods. We examined the changes by the…
2018 American Transplant Congress
Transplantation of Restored Kidneys from Living Related Donors after Small Renal Tumor Resection: Report of 5 Cases
Y. Ogawa,¹ S. Shiroma,² K. Kojima,² R. Mannami,² M. Mannami,² N. Mitsuhata,² M. Nishi,⁴ H. Afuso.³
¹Urology, Tokyo-West Tokushukai Hospital, Akishima, Tokyo, Japan; ²Urology, Uwajima Toikushukai Hospital, Uwajima, Ehime, Japan; ³Urology, Okinawa Chubu Tokushukai Hospital, Okinawa, Japan; ⁴Urology, Saint Martin's Hospital, Sakaide, Kagawa, Japan.
Purpose: We launched a clinical trial registered at ClinicalTrials.gov that aimed to study the utility and safety of restored kidney transplantation between family members using…
2018 American Transplant Congress
High Kidney Donor Profile Index (KDPI) Donor Kidneys: Use Them, Don't Lose Them!
D. Harriman, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, M. Gautreaux, W. Doares, S. Kaczmorski, R. Stratta.
Surgery, Medicine, Pathology, Pharmacy, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Introduction: With the development of the Kidney Donor Profile Index (KDPI) and a new Kidney Allocation System (KAS) implemented on 12/4/14, the expanded criteria donor…
2018 American Transplant Congress
Multi-Center Examination of the Reliability and Validity of the Live Donor Assessment Tool (LDAT) as an Enhancement to the Psychosocial Evaluation of Living Donors
D. LaPointe Rudow,¹ S. Jowsey-Gregoire,² F. Desrosiers,³ J. Trompeta,⁴ LDAT Study Group.¹
¹RMTI, Mount Sinai Hosptial, NY, NY; ²Mayo Clinic, Rochester, MN; ³NYPH, NY, NY; ⁴UCSF, San Francisco, CA.
Purpose: The LDAT is the first psychosocial assessment tool developed to standardize live donor (LD) psychosocial evaluations (PsychE). It assesses motivation, LD knowledge/expectations, support, closeness…
2018 American Transplant Congress
The THINKER Trial: Quality of Life Results at 6- and 12-Month Follow-Up among Hepatitis C-Negative Patients Who Received Kidney Transplants from Deceased Donors with Hepatitis C Infection
V. Potluri, D. Goldberg, A. Peter, B. Emily, B. Roy, S. Deirdre, M. Levine, J. Trofe-Clark, M. Bleicher, S. Goral, A. Sicilia, S. Nazarian, R. Reddy, P. Porrett, P. Reese.
Univ of Pennsylvania, Philadelphia, PA.
Background: Short-term (6-month) data from the first 10 subjects in the pilot THINKER-1 trial (NCT02743897; funder: Merck) suggested that kidneys from HCV-infected donors could be…

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