ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Donors"

  • 2015 American Transplant Congress

    Causes of Poor Renal Function of Kidney Transplants from Uncontrolled Donation After Cardiac Death Donors (UDCDD)

    M. Molina, E. González, E. Gutiérrez, E. Morales, E. Hernández, A. Sevillano, N. Polanco, J. Cabrera, M. Praga, A. Andres.

    Nephrology, Hospital 12 de Octubre, Madrid, Spain.

    INTRODUCTION: Kidneys grafts from UDCDD have higher ischemia injury. It develops in higher primary non function, lower graft survival and worst renal function compared to…
  • 2015 American Transplant Congress

    Prospective Measurement of Plasma Neutrophil Gelatinase-Associated Lipoprotein in Living Kidney Donors

    Y. Yoon,1 K. Choi,2 D. Joo,3 K. Huh,3 M. Kim,3 S. Kim,3 Y. Kim,3 S. Yang,2 W. Han.1

    1Department of Urology, Yonsei University College of Medicine, Seoul, Korea; 2Department of Urology, CHA University, Seongnam-si, Korea; 3Department of Transplantation Surgery, Yonsei University College of Medicine, Seoul, Korea.

    Introduction: Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker for acute kidney injury. This study was conducted to determine the clinical implications of perioperative plasma NGAL…
  • 2015 American Transplant Congress

    Effect of Distinct Immunosuppressive Protocols On the Profile of Cytokines Expression in Renal Transplant Recipients of Extended Criteria Donor Kidneys

    C. Montoro Mazeti,1 C. Zangrossi Dezotti,1 I. Fernandes-Charpiot,1,2 H. Caldas,1 M. Baptista,1,2 M. Abbud Filho.1,2,3

    1Laboratory of Immunology and Experimental Transplantation, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto, SP, Brazil; 2Department of Medicine, Division of Nephrology, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto, SP, Brazil; 3Urology and Nephrology Institute, Urology and Nephrology Institute, Sao Jose do Rio Preto, SP, Brazil.

    Background: Transplant recipients (RTx) of kidneys classified as extended criteria (ECD) seems to have worst outcomes when compared with RTx of standard kidneys (SCD) and…
  • 2015 American Transplant Congress

    Ischemic Cholangiopathy Following Liver Transplantation from Donation After Circulatory Death Donors: Role of Tissue Plasminogen Activator Flush

    C. Kubal,1 R. Mangus,1 J. Fridell,1 M. Wingler,2 S. Nagai,1 B. Ekser,1 J. Tector.1

    1Department of Surgery, Indiana University, Indianapolis, IN; 2Indiana Organ Procurement Organization, Indianapolis, IN.

    Background: Formation of microthrombi within the peribiliary arterial plexus causing necrosis of biliary epithelium may be responsible for ischemic cholangiopathy (IC) after donation after circulatory…
  • 2015 American Transplant Congress

    "In-House" Controlled Oxygenated Rewarming After Initial Static Cold Storage: First Clinical Application in Marginal Donor Livers

    D. Hoyer,1 Z. Mathé,1 A. Gallinat,1 A. Canbay,2 J. Treckmann,1 U. Rauen,3 A. Paul,1 T. Minor.4

    1General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany; 2Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany; 3Institute of Physiological Chemistry, University Hospital Essen, Essen, Germany; 4Surgical Research Division, University Hospital Bonn, Bonn, Germany.

    IntroductionControlled oxygenated rewarming of cold stored livers by machine perfusion demonstrated a strong protective effect in preclinical studies. Here we report on the first clinical…
  • 2015 American Transplant Congress

    Delivery of Heme Oxygenase-1-Cell Penetrating Peptide (HO-1-CPP) Into Hepatocytes, Kupffer and Islet Cells in In Vitro and Ex Vivo Models of Cold Ischemia

    A. Venkatachalam,1 C. Wood,1 Q. Hu,1 I. Alwayn.2

    1Surgery, Dalhousie University, Halifax, NS, Canada; 2Surgery, Pathology, Microbiology & Immunology, Surgical Lead Multi Organ Transplant Program, QEII Health Sciences Center, Dalhousie University, Halifax, NS, Canada.

    In an attempt to increase the number of donor organs available to transplantation extended criteria donor (ECD) organs are more frequently considered. Unfortunately, ECD organs…
  • 2015 American Transplant Congress

    Evaluation of Geographically Distant Living Kidney Donors: A Barrier to Living Donation?

    F. Weng, N. Dhillon, L. Davis, R. Goldberg, A. Patel, K. Tibaldi, M. Morgievich, S. Mulgaonkar.

    Renal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ.

    Introduction: Living kidney donors often live far from the recovering transplant center where they donate. We sought to determine (1) characteristics of these geographically distant,…
  • 2015 American Transplant Congress

    Long-Term Outcomes of Transplantation Using Kidneys from Expanded Criteria Donors

    O. Aubert,1 Kamar,2 Vernerey,1 Viglietti,1 Duong van Huyen,1 Rabant,1 Rostaing,2 Congy,2 Guilbeau-Frugier,2 Martinez,1 Delahousse,1 Glotz,1 Jouven,1 Legendre,1 Lefaucheur,1 Loupy.1

    1Paris Translational Research Center for organ Transplantation, Paris, France; 2Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France.

    BackgroundSince the initial definition of ECD established in 2002, their use worldwide has evolved unequally, resulting in a high discard rate. A better understanding of…
  • 2015 American Transplant Congress

    Kidneys from Living Donors With High Body Mass Index Do Not Have Inferior Outcomes

    K. Koutroutsos, S. Chong, D.-A. Moutzouris, R. Charif, J. Galliford, J. McDermott, D. Taube, M. Loucaidou.

    Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    The disparity between donor kidney availability and demand has increased utilization of kidneys from marginal living donors. Data regarding outcome of transplantation from living donors…
  • 2015 American Transplant Congress

    Correlation Between Level of Biomarkers Measured in Perfusate of Machine-Preserved ECD/DCD Kidneys and Post-Transplant Graft Function

    E. Ablorsu,1 S. Zouwail,2 P. Laftsidis,1 B. Cook,1 L. Szabo.1

    1Cardiff Transplant Unit, University Hospital for Wales, Cardiff, United Kingdom; 2The Medical Biochemistry and Immunology Department, University Hospital for Wales, Cardiff, United Kingdom.

    Background:DCD and ECD kidneys are associated with higher risk of failure compare to SCD kidneys. Therefore we see increasing need to identify sensitive tool to…
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