ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Donors"

  • 2018 American Transplant Congress

    Are Donation after Cardiac Death (DCD) Kidneys Unsuitable for Pediatric Recipients?

    M. MacConmara,1 S. Levea,2 C. Hwang.1

    1Surgery, UT Southwestern Medical Center, Dallas, TX; 2Medicine, UT Southwestern Medical Center, Dallas, TX.

    Introduction: Despite the fact that the number of pediatric patients listed for kidney transplantation far exceeds the supply of deceased donor kidneys, there is a…
  • 2018 American Transplant Congress

    Donation after Circulatory Death Donor Liver Transplantation without Ischemic Cholangiopathy: Is It Time to Expand DCD Liver Donor Pool?

    C. Kubal,1 P. Mihaylov,1,2 B. Ekser,1 A. Cabrales,1 J. Fridell,1 R. Mangus.1

    1Transplant Surgery, Indiana University, Indianapolis; 2Division of General Surgery, IRCCS Policlinico San Matteo Foundation, University of Pavia, Lombardy, Italy.

    Background: To prevent ischemic cholangiopathy (IC) after liver transplantation (LT), a protocol optimizing peri-operative conditions along with thrombolytic (tissue plasminogen activator) donor flush during DCD…
  • 2018 American Transplant Congress

    Incidence Trends among Deceased Liver Transplant Recipients in the United States, 2011-2016: A Propensity Score-Matched Study

    R. Schilke, M. Safwan, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai.

    Transplant Institute, Henry Ford Hospital, Detroit, MI.

    BackgroundDonation after cardiac death (DCD) donor liver graft is a known risk factor for graft failure secondary to primary non-function (PNF) and/or diffuse cholangiopathy (DC).…
  • 2018 American Transplant Congress

    Intensified Immunosuppression Improves Early Renal Allograft Function after Transplantation in a Porcine Model with Extended Asystolic Warm Ischemic Time

    M. Xu,1 X. Wang,1 S. Garcia-Aroz,1 B. Banan,1 B. Rabe,1 Z. Zhang,1 J. Jia,1 G. Upadhya,1 P. Manning,2 J. Gaut,3 Y. Lin,1 W. Chapman.1

    1Department of Surgery, Section of Abdominal Transplantation, Washington University School of Medicine, St. Louis, MO; 2Arch Oncology, St. Louis, MO; 3Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.

    PURPOSE: Extensive ischemia-reperfusion injury significantly increases the immunogenicity of renal allograft which may be associated with increased risk of acute rejection (AR). This study investigated…
  • 2018 American Transplant Congress

    Reliability of Deceased Donor Procurement Biopsy Images at the Time of Kidney Allocation

    S. Mansour,1 E. Hall,2 P. Reese,3 Y. Jia,1 H. Thiessen-Philbrook,1 G. Moeckel,1 F. Weng,4 P. Revelo,2 M. Khalighi,2 A. Trivedi,5 M. Doshi,6 B. Schroppel,7 C. Parikh.1

    1Yale University School of Medicine, New Haven; 2University of Utah School of Medicine, Salt Lake City; 3Perelman School of Medicine at the University of Pennsylvania, Philadelphia; 4Saint Barnabas Medical Center, Livingston; 5Hartford Hospital, Hartford; 6Wayne State University, Detroit; 7University Hospital, Ulm, Germany.

    Histological findings of procurement deceased-donor kidney biopsies contribute to organ allocation decisions. Representative images of pathology on biopsy slides are often uploaded into United Network…
  • 2018 American Transplant Congress

    Self-Reported Post-Surgical Pain Following Living Kidney Donation

    A. Fleishman,1 J. Schold,2 P. Morrissey,3 J. Whiting,4 J. Vella,4 L. Kayler,5 D. Katz,6 J. Jones,6 B. Kaplan,7 M. Pavlakis,1 D. Mandelbrot,8 J. Rodrigue.1

    1Beth Israel Deaconess Medical Center, Boston; 2Cleveland Clinic, Boston; 3Rhode Island Hospital, Providence; 4Maine Medical Center, Portland; 5University of Buffalo, Buffalo; 6University of Iowa, Iowa City; 7May Clinic, Scottsdale; 8University of Wisconsin, Madison.

    The Kidney Donor Outcomes Cohort (KDOC) is an NIH-funded observational cohort study evaluating outcomes in living kidney donors (LKDs) at 6 US centers. LKDs completed…
  • 2018 American Transplant Congress

    Predicting Early and Late eGFR Variability in Kidney Transplant Recipients

    K. Soliman, D. Taber, S. Zemin, V. Rao.

    Department of Medicine and Department of Surgery, MUSC, Charleston, SC.

    Introduction: eGFR variability is a known risk factor for graft loss. It is unclear what modifiable factors are significantly associated with this variability and if…
  • 2018 American Transplant Congress

    Outcomes of Renal Transplants from Donors with Positive Blood or Urine Cultures

    L. Chen,1 D. Kamiyama,2 L. Francalacci,1 E. Zhu,2 M. Donnelley,2 N. Clayton,2 K. Alman,1 A. De Mattos,1 J. Brown.3

    1Transplant Nephrology, UC Davis Medical Center, Sacramento, CA; 2Pharmacy, UC Davis Medical Center, Sacramento, CA; 3Infectious Diseases, UC Davis Medical Center, Sacramento, CA.

    OBJECTIVES: To evaluate outcomes in renal transplant recipients who received organs from donors with positive blood or urine cultures.METHODS: We performed a retrospective, single-center study…
  • 2018 American Transplant Congress

    Use of Hepatitis-C Treatments after Kidney Transplantation: Impact of the Direct-Acting Antiviral Era

    K. Lentine, D. Axelrod,2 R. Bloom,3 H. Xiao,1 D. Segev,4 T. Alhamad,5 H. Randall,1 R. Ouseph,1 V. Dharnidharka,5 D. Brennan,4 N. Lam,6 A. Naik,7 G. Hess,8 B. Kaiske,9 M. Schnitzler.1

    1Saint Louis U, St. Louis; 2Lahey, Burlington; 3U Penn, Philadelphia; 4Johns Hopkins, Baltimore; 5Washington U, St. Louis; 6U Alberta, Edmonton, Canada; 7U Michigan, Ann Arbor; 8Hennepin, Minneapolis; 9Symphony Health, Conshohocken.

    Hepatitis C virus (HCV) infection in kidney transplant (KTx) donors or recipients has correlated with adverse outcomes, partly due to limited treatment options. Development of…
  • 2018 American Transplant Congress

    Livers from Donation after Circulatory Death Donors Can Be Safely Used for Retransplantation

    O. van Leeuwen,1 M. van Reeven,2 J. Erdmann,3 H. Metselaar,4 A. van den Berg,5 B. van Hoek,6 W. Polak,2 R. Porte.1

    1Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; 2Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands; 3Department of Surgery, Leiden University Medical Center, Leiden, Netherlands; 4Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Netherlands; 5Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, Netherlands; 6Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands.

    Introduction: After donation after circulatory death (DCD) liver transplantation (LT), non-anastomotic biliary strictures (NAS) and early allograft dysfunction (EAD) are more frequently observed than after…
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