ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Donors"

  • 2017 American Transplant Congress

    Intended and Unexpected Impact of the New Kidney Allocation System on a Large Volume Transplant Program.

    A. de Mattos, M. Alnimri, L.-X. Chen, J. Sageshima, C. Santhanakrishnan, R. Perez.

    University of California Davis, Sacramento, CA

    On December 4, 2014 the new Kidney Allocation System (KAS) went into effect in the United States. The intentions of KAS were to increase the…
  • 2017 American Transplant Congress

    Warm Ischemic Time as an Additive Predictor of Graft Survival in KDPI/KDRI Era of Kidneys from Donors After Cardiac Death: A Single-Center Experience Over Three Decades.

    M. Kusaka,1 Y. Kubota,1 H. Takahashi,2 H. Sasaki,1 M. Takenaka,1 N. Fukami,1 T. Kenmochi,3 R. Shiroki,1 K. Hoshinaga.1

    1Urology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan; 2Division of Medical Statistics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan; 3Organ Transplant Surgery, Fujita Health University School of Medicine, Toyoake, Aichi, Japan

    It is important to predict the outcome of grafts prior to kidney transplantation and establish an appropriate allocation system, particularly to consider expanded criteria donors…
  • 2017 American Transplant Congress

    Intraomental Non-Purified Islet Transplantation Isolated from DCD Donor Pancreas.

    S. Wang, G. Pei, Y. Liu, Z. Wang, B. Zhang, Y. Xie, J. Wang, Z. Shen.

    Transplant Center, Tianjin First Center Hospital, Tianjin, China

    Objective: We have proved that omentum was a more efficient site to perform non-purified islet transplantation with more safety in Beagle dog islet auto-transplantation model.…
  • 2017 American Transplant Congress

    A Humanized Anti-CD47 Monoclonal Antibody Therapy Alleviates Ischemia-Reperfusion Injury of Porcine Renal Allografts Donated After Cardiac Death.

    M. Xu,1 B. Banan,1 X. Wang,1 D. Chirumbole,1 B. Rabe,1 S. Garcia-Aroz,1 D. Nayak,1 Z. Zhang,1 J. Jia,1 G. Upadhya,1 J. Gaut,2 P. Manning,3 Y. Lin,1 W. Chapman.1

    1Department of Surgery, Washington University School of Medicine, St. Louis; 2Department of Pathology and Immunology, Washington University School of Medicine, St. Louis; 3Tioma Therapeutics, Inc, St. Louis

    PURPOSE: This study investigated whether the blockade of the CD47 signaling pathway, which is involved in vascular endothelial nitric oxide regulation, reduces ischemia-reperfusion injury (IRI)…
  • 2017 American Transplant Congress

    Higher Mortality Among Candidates Who Refuse to Accept DCD Kidney Offers.

    M. Bowring, A. Massie, D. Segev.

    JHU, Baltimore

    DCD kidneys provide survival benefit but continue to be declined and discarded at elevated rates. We aimed to characterize the potential benefit or harm associated…
  • 2017 American Transplant Congress

    Estimating Donor Organ Quality with Baseline Histology and Kidney Donor Risk Index for Predicting Graft Outcomes in Deceased Donor Kidney Transplantation.

    K. Park,1 S. Park,2 H. Park,2 J. Park,1 H. Chung,1 M. Kim,3 H. Cho,2 J. Lee.1

    1Internal Medicine, Ulsan University Hospital, Ulsan, Republic of Korea; 2Surgery, Ulsan University Hospital, Ulsan, Republic of Korea; 3Pathology, Ulsan University Hospital, Ulsan, Republic of Korea

    Background: Donor organ quality is a key determinant of graft outcomes in deceased donor kidney transplantation (DDKT). The effect of baseline histology at the time…
  • 2017 American Transplant Congress

    Kidney Re-Transplantation (KRTx) from Donation After Cardiocirculatory Death (DCD)-Standard Criteria Donors (SCD).

    M. Khan, B. Alradawna, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, A. Palanisamy, M. Gautreaux, W. Doares, S. Kaczmorsky, R. Stratta.

    Transplant, Wake Forest Baptist Medical Center, Winston Salem, NC

    Donation after cardiac death (DCD) donor kidneys increase the organ pool but use in kidney retransplantation (KRTx) has been questioned due to higher rates of…
  • 2017 American Transplant Congress

    Serva NB1 versus Vitacyte Collagenase: Comparable Human Islet Isolation Outcomes Using DCD Donor Pancreas in China.

    Y. Liu, P. Sun, J. Zou, G. Wang, T. Liu, L. Wang, S. Wang.

    Transplant Center, Tianjin First Center Hospital, Tianjin, China

    Objective This study was designed to retrospectively compare the effect of Serva NB1 collagenase between Vitacyte collagenase on islet isolation of DCD pancreas in China.…
  • 2017 American Transplant Congress

    CD47 Blockade Reduces Ischemia/Reperfusion Injury in Donation After Cardiac Death Rat Kidney Transplantation.

    X. Wang,1 M. Xu,1 J. Jia,1 Z. Zhang,1 J. Gaut,2 G. Upadhya,1 P. Manning,3 Y. Lin,1 W. Chapman.1

    1Department of Surgery, Washington University School of Medicine, Saint Louis; 2Pathology and Immunology, Washington University School of Medicine, Saint Louis; 3Tioma Therapeutics, Saint Louis

    Purpose: We evaluated the potential effects of antibody-mediated CD47 blockade to modulate vascular endothelial nitric oxide activity and reduce ischemia reperfusion injury in a rat…
  • 2017 American Transplant Congress

    Higher Mortality Among Candidates Who Refused Increased-Infectious Risk Kidney Offers.

    M. Bowring, L. Kucirka, A. Massie, C. Holscher, D. Segev.

    JHU, Baltimore

    Increased infectious risk donors (IRD) are younger and healthier than most deceased donors, but IRD kidneys are discarded at higher rates despite potential benefit to…
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