ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Donors"

  • 2017 American Transplant Congress

    Higher Mortality Among Candidates Who Refuse to Accept DCD Kidney Offers.

    M. Bowring, A. Massie, D. Segev.

    JHU, Baltimore

    DCD kidneys provide survival benefit but continue to be declined and discarded at elevated rates. We aimed to characterize the potential benefit or harm associated…
  • 2017 American Transplant Congress

    Estimating Donor Organ Quality with Baseline Histology and Kidney Donor Risk Index for Predicting Graft Outcomes in Deceased Donor Kidney Transplantation.

    K. Park,1 S. Park,2 H. Park,2 J. Park,1 H. Chung,1 M. Kim,3 H. Cho,2 J. Lee.1

    1Internal Medicine, Ulsan University Hospital, Ulsan, Republic of Korea; 2Surgery, Ulsan University Hospital, Ulsan, Republic of Korea; 3Pathology, Ulsan University Hospital, Ulsan, Republic of Korea

    Background: Donor organ quality is a key determinant of graft outcomes in deceased donor kidney transplantation (DDKT). The effect of baseline histology at the time…
  • 2017 American Transplant Congress

    Kidney Re-Transplantation (KRTx) from Donation After Cardiocirculatory Death (DCD)-Standard Criteria Donors (SCD).

    M. Khan, B. Alradawna, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, A. Palanisamy, M. Gautreaux, W. Doares, S. Kaczmorsky, R. Stratta.

    Transplant, Wake Forest Baptist Medical Center, Winston Salem, NC

    Donation after cardiac death (DCD) donor kidneys increase the organ pool but use in kidney retransplantation (KRTx) has been questioned due to higher rates of…
  • 2017 American Transplant Congress

    Serva NB1 versus Vitacyte Collagenase: Comparable Human Islet Isolation Outcomes Using DCD Donor Pancreas in China.

    Y. Liu, P. Sun, J. Zou, G. Wang, T. Liu, L. Wang, S. Wang.

    Transplant Center, Tianjin First Center Hospital, Tianjin, China

    Objective This study was designed to retrospectively compare the effect of Serva NB1 collagenase between Vitacyte collagenase on islet isolation of DCD pancreas in China.…
  • 2017 American Transplant Congress

    CD47 Blockade Reduces Ischemia/Reperfusion Injury in Donation After Cardiac Death Rat Kidney Transplantation.

    X. Wang,1 M. Xu,1 J. Jia,1 Z. Zhang,1 J. Gaut,2 G. Upadhya,1 P. Manning,3 Y. Lin,1 W. Chapman.1

    1Department of Surgery, Washington University School of Medicine, Saint Louis; 2Pathology and Immunology, Washington University School of Medicine, Saint Louis; 3Tioma Therapeutics, Saint Louis

    Purpose: We evaluated the potential effects of antibody-mediated CD47 blockade to modulate vascular endothelial nitric oxide activity and reduce ischemia reperfusion injury in a rat…
  • 2017 American Transplant Congress

    Higher Mortality Among Candidates Who Refused Increased-Infectious Risk Kidney Offers.

    M. Bowring, L. Kucirka, A. Massie, C. Holscher, D. Segev.

    JHU, Baltimore

    Increased infectious risk donors (IRD) are younger and healthier than most deceased donors, but IRD kidneys are discarded at higher rates despite potential benefit to…
  • 2017 American Transplant Congress

    Steatotic Human Livers Show Inferior Function Compared to Non-Steatotic Livers During Ex-Situ Viability Assessment by Oxygenated Machine Perfusion.

    N. Karimian,1 V. Huang,1 F. Fontan,1 M. Aburawi,1 S. Geerts,1 S. Mert,1 I. Beijert,2 R. Porte,2 M. Yarmush,1 K. Uygun,1 J. Markmann,1 H. Yeh.1

    1Division of Transplantation, Massachusetts General Hospital, Boston; 2Division of Transplantation, University Medical Center Groningen, Groningen, Netherlands

    Fatty livers are frequently declined for transplantation due to high risk of primary non-function. Ex-situ oxygenated machine perfusion (MP) is superior to static cold storage…
  • 2017 American Transplant Congress

    Evaluation of Outcomes in Renal Transplantation Using Machine Perfusion for the Preservation of Kidneys from Expanded Criteria Donor.

    E. Savoye, M. Macher, Kidney Working Group, C. Legeai, C. Antoine.

    Agence de la Biomedecine, Saint Denis La Plaine, France

    Introduction:The shortage of kidney grafts led to retrieve organs from old donors with one or more co-morbidities, considered as “expanded criteria donors” (ECD). In France,…
  • 2017 American Transplant Congress

    Proteins in Preservation Fluid Predict Delayed Graft Function of Kidneys from Donors After Circulatory Death.

    B. van Balkom,1 H. Gremmels,1 L. Ooms,4 R. Toorop,2 F. Dor,5 O. de Jong,1 L. Michielsen,1 G. de Borst,2 W. de Jager,3 A. van Zuilen,1 M. Verhaar.1

    1Nephrology and Hypertension, UMC Utrecht, Utrecht, Netherlands; 2Vascular Surgery, UMC Utrecht, Utrecht, Netherlands; 3Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands; 4Surgery, Erasmus MC, Rotterdam, Netherlands; 5Renal and Transplant Services, Imperial College Healthcare NHS Trust, London, United Kingdom

    Background and objectivesKidney transplantation is the preferred treatment for end-stage kidney disease, and donor kidney shortage urges proper donor-recipient matching. Zero-hour biopsies provide predictive value…
  • 2017 American Transplant Congress

    Donor Warm Ischemic Time >80min Is an Important Predictor of Kidney Graft Survival from Donors After Cardiac Death.

    J. Chen,1 D. Mikhail,2 H. Sharma,3 A. Hijazi,1 D. Nap,1 L. Stitt,4 J. Jevnikar,5 M. Cooper,6 P. Luke,2 A. Sener.2

    1Schulich School of Medicine & Dentistry, London, Canada; 2Urology, Western University, London, Canada; 3General Surgery, Western University, London, Canada; 4LW Stitt Statistical Services, London, Canada; 5Engineering, Ryerson University, Toronto, Canada; 6Georgetown University, Washington

    We analyzed UNOS data to determine how donor warm ischemic time (WIT), donor BMI, donor hypertension (dHTN), cold ischemic time (CIT), and vasopressin use in…
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