2018 American Transplant Congress
The THINKER Trial: Quality of Life Results at 6- and 12-Month Follow-Up among Hepatitis C-Negative Patients Who Received Kidney Transplants from Deceased Donors with Hepatitis C Infection
Univ of Pennsylvania, Philadelphia, PA.
Background: Short-term (6-month) data from the first 10 subjects in the pilot THINKER-1 trial (NCT02743897; funder: Merck) suggested that kidneys from HCV-infected donors could be…2018 American Transplant Congress
Waiting for the Optimal Donor for MCS Patients Awaiting Heart Transplant
Cedars Sinai Medical Center, Los Angeles.
Purpose: Patients (pts) bridged with mechanical circulatory support (MCS) may require more optimal donors for best outcome compared to non-bridged transplant recipients. MCS pts have…2018 American Transplant Congress
Temporal Trends, Predictive Factors, and Regional Differences in Discard of Increased-Risk Kidneys
Surgery, Maine Medical Center, Portland, ME.
Purpose: Public Health Service (PHS) criteria designate certain deceased donors (DD) as entailing increased risk (IR) for disease transmission, and these constitute an expanding proportion…2018 American Transplant Congress
Impact of Donation after Cardiac Death Allografts on Outcome Following Liver Transplantation for Fulminant Hepatic Failure: An Analysis of the UNOS Database
Scarcity of donor organs in liver transplantation (LT) has necessitated consideration of extended criteria donors (ECDs), including donation after cardiac death (DCD) donors. The narrow…2018 American Transplant Congress
Human Atrial Natriuretic Peptide (hANP) in Cold Storage of Donation after Cardiac Death Livers: A New Tool for Protecting Vascular Endothelia?
Aim: Current critical shortage of donor organs has led to acceptance of donation after cardiac death (DCD) livers for transplantation. Human atrial natriuretic peptide (hANP)…2018 American Transplant Congress
Lack of Efficacy of Eculizumab for Prevention of Delayed Graft Function (DGF) in Deceased Donor Kidney Transplant Recipients
DGF portends poor short- and long-term renal function, increases cost, and may reduce graft survival. We studied the safety/efficacy of eculizumab (ECU), a C5 convertase…2018 American Transplant Congress
Unilateral vs. Bilateral Dual Kidney Transplantation: University of Bologna Experience
One option for using organs from donors with a suboptimal nephron mass, e.g. expanded criteria donors (ECD) kidneys, is dual kidney transplantation (DKT)Methods: Ninety-three DKT…2018 American Transplant Congress
Outcomes after Kidney Transplant (KTx) from Deceased Donors (DD) Aged ≥ 70
Background:There has been an increase in DD aged 70 or greater and transplant centers are reluctant to accept these organs. The aim of this study…2018 American Transplant Congress
Transplantation of DCD Livers vs. NDD and LDLT: Is There a Difference in Post-Transplant Kidney Dysfunction?
Background. Recipients of donation after circulatory death (DCD) grafts are reportedly at higher risk of developing post liver transplant (LT) renal dysfunction. Our aim was…2017 American Transplant Congress
A Humanized Anti-CD47 Monoclonal Antibody Therapy Alleviates Ischemia-Reperfusion Injury of Porcine Renal Allografts Donated After Cardiac Death.
PURPOSE: This study investigated whether the blockade of the CD47 signaling pathway, which is involved in vascular endothelial nitric oxide regulation, reduces ischemia-reperfusion injury (IRI)…
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