ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Donors"

  • 2018 American Transplant Congress

    Aggressive Pursuit of Donation after Cardiac Death Kidney Donors with High Kidney Donor Profile Index: Good Use of Resources?

    J. Rogge, C. Hostetler, B. Nicely, S. Rudich.

    Clinical Division, Gift of Life Michigan, Ann Arbor, MI.

    Pursuit of donation after cardiac death (DCD) organ donors requires a significant investment in resources. As an Organ Procurement Organization which very aggressively pursues such…
  • 2018 American Transplant Congress

    Viability Outcomes for Donor Livers Discarded Due to Steatosis Following Extra-Corporeal Machine Perfusion of the Liver

    Y. Boteon,1,2 R. Laing,1,2 D. Neil,2 A. Schlegel,2 J. Attard,1,2 G. Reynold,1 P. Muiesan,2 D. Mirza,2 S. Afford,1 H. Mergental.2

    1National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; 2Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.

    Background: Steatosis is the main reason for discarding donor livers worldwide. Ex-vivo machine perfusion offers superior preservation for marginal organs and permits viability testing during…
  • 2018 American Transplant Congress

    Donor Acute Kidney Injury Does Not Affect Fibrosis on 1 Year Post-Transplant Kidney Biopsy

    D. van der Windt, X. Chen, K. Lemon, C. Wu, N. Shah, R. Mehta, C. Puttarajappa, P. Sood, S. Hariharan, A. Ganoza, M. Wijkstrom, A. Humar, A. Tevar.

    Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA.

    PurposeThe use of kidneys from deceased donors with acute kidney injury (AKI) at the time of donation is a potential method by which to expand…
  • 2018 American Transplant Congress

    QPI-1002, a siRNA Targeting p53: Improvement in Outcomes Following Acute Kidney Injury (AKI): Cardiac Surgery to AKI Donors

    J. Tchervenkov,2 E. Squiers,1 R. Stratta,3 D. Odenheimer,2 D. Rothenstein,2 QPI-1002 DGF Study Group.

    1Quark Pharmaceuticals, Fremont; 2McGill University Health, Montreal, Canada; 3Wake Forest School of Medicine Centre, Winston-Salem.

    Background: QPI-1002 has been observed to statistically reduce the incidence, severity and duration of AKI in a large Phase 2 study of AKI following cardiac…
  • 2018 American Transplant Congress

    Impact of Donor Hepatectomy Time during Organ Procurement in Donation after Circulatory Death Liver Transplantation; The United Kingdom Experience

    S. Farid, A. Magdy, D. Vijayanand, V. Upasani, S. Willis, A. Barlow, H. Ernest, A. Niaz.

    St James University Hospital, Leeds, United Kingdom.

    IntroductionNo data exists to evaluate the impact of hepatectomy time (HT) during donation after cardiac death (DCD) procurement on short and long-term outcomes following liver…
  • 2018 American Transplant Congress

    Unique Recipient Benefits with Paired Kidney Donation

    J. Buggs,1 E. Rogers,2 V. Bowers.1

    1Transplant Surgery, Tampa General Medical Group, Tampa General Hospital, Tampa, FL; 2Transplant Research, Tampa General Hospital, Tampa, FL.

    Introduction: Kidney transplantation is the treatment choice for ESRD with improved survival and cost benefit compared with dialysis. The imbalance of supply over demand along…
  • 2018 American Transplant Congress

    A Study to Identify Marginal Factors for Donors of Pancreas Transplantation in Japan

    T. Ito, T. Kenmochi, K. Kurihara, N. Aida.

    Department of Transplantation and Regenerative Medicine, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.

    ObjectiveAlthough pancreas transplantation is generally performed with donors in less-than-ideal condition in Japan, such as over 40% of donors being over 45 years of age…
  • 2018 American Transplant Congress

    Evolution of Very Old Donor Grafts

    S. Jiménez Alvaro,1 A. Fernández Rodriguez,1 C. Galeano Alvarez,1 S. Elías Treviño,1 J. Burgos,2 F. Liaño García.1

    1Nephrology, Hospital Ramón y Cajal, Madrid, Spain; 2Nephrology, Hospital Ramón y Cajal, Madrid, Spain; 3Nephrology, Hospital Ramón y Cajal, Madrid, Spain; 4Nephrology, Hospital Ramón y Cajal, Madrid, Spain; 5Urology, Hospital Ramón y Cajal, Madrid, Spain; 6Nephrology, Hospital Ramón y Cajal, Madrid, Spain.

    Introduction: The need to implement the pool of donors has led to the use of organs from older donors, as has been described in several…
  • 2018 American Transplant Congress

    DCD Kidneys with Remuzzi Scores of 4-5 Can Be Accepted for Solitary Kidney Transplantation

    X-.P. Yuan, C-.B. Chen, Y. Zheng, J. Zhou, C. Wang, X. He.

    Organ Transplant Center, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.

    Background Baseline chronic donor kidney injury is usually scored using Remuzzi's classification. It has been suggested that kidneys with Remuzzi scores of 0-3 can be…
  • 2018 American Transplant Congress

    A Phase I/II, Double-Blind, Placebo-Controlled Study Assessing Safety and Efficacy of C1 Esterase Inhibitor for Prevention of Delayed Graft Function in Deceased Donor Kidney Transplant Recipients

    S. Jordan,1 J. Choi,1 O. Aubert,2 M. Haas,3 A. Loupy,2 E. Huang,1 A. Peng,1 I. Kim,1 S. Sethi,1 S. Louie,1 D. Puliyanda,1 A. Vo.1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; 2Paris Translational Research Center for Organ Transplantation, Necker Hospital, Paris, France; 3Pathology, Cedars-Sinai Medical Center, Los Angeles, CA.

    Background: Delayed graft function (DGF)in kidney allograft recipients is traditionally defined as need for dialysis during the first week after transplantation. DGF is related to…
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