Articles tagged "Donors, non-heart-beating"

2020 American Transplant Congress
Benefits of Normothermia Regional Perfusion (NRP), Hypothermic Machine Perfusion (HMP) and Short Cold Ischemia Time (CIT) for Kidney Transplants with Controlled Donation after Circulatory Death (cDCD)
E. Savoye¹, C. Legeai¹, J. Branchereau², S. Gay³, S. Drouin⁴, F. Gaudez⁵, B. Veber⁶, J. Venhard⁷, G. Cheisson⁸, T. Kerforne⁹, O. Bastien¹, C. Antoine¹
¹Agence de la Biomedecine, La Plaine Saint Denis, France, ²CHU Nantes, Nantes, France, ³CH Annecy, Annecy, France, ⁴CHU Pitié Salpetriere, Paris, France, ⁵CHU Saint Louis, Paris, France, ⁶CHU Rouen, Rouen, France, ⁷CHU Tours, Tours, France, ⁸CHU Kremlin-Bicetre, Kremlin-Bicetre, France, ⁹CHU Poitiers, Poitiers, France
*Purpose: cDCD are considered as extended criteria donors with poorer kidney transplant outcomes and high delayed graft function (DGF) rate. We built a French national…
2020 American Transplant Congress
Livers from Donation after Cardiac Death (DCD) Offer – Accept or Decline?
T. Ishaque, M. G. Bowring, J. D. Motter, Y. Yu, S. Yu, A. B. Kernodle, J. G. Wang, S. Getsin, D. L. Segev, A. B. Massie
Johns Hopkins University, Baltimore, MD
*Purpose: Given the shortage of deceased-donor livers, donation after cardiac death (DCD) provides an opportunity to expand the donor pool. Due to concern over the…
2020 American Transplant Congress
Initial North American Experience in Renal Transplantation from Medical Assistance in Dying Donors
M. A. Levine, S. Sami, A. Sener, P. Luke
Surgery, London Health Sciences Centre, London, ON, Canada
*Purpose: In 2016, Canadian federal legislation was passed creating a regulatory framework for medical assistance in dying (MAiD) for individuals who are suffering from a…
2020 American Transplant Congress
Increased Mitochondrial Metabolic Enzymes are Associated with Superior Kidney Function after Normothermic Ex-Vivo Kidney Perfusion-A Proteomics Study
C. McEvoy¹, S. Clotet-Freixas¹, T. Tokar², C. Pastrello², S. Reid³, I. Batruch⁴, A. RaoPeters⁵, P. Urbanellis¹, M. Kaths¹, S. Farkona¹, J. Van³, B. Urquhart⁵, I. Jurisica², L. Robinson⁶, M. Selzner¹, A. Konvalinka¹
¹Toronto General Hospital Research Institute and Multi-Organ Transplant, UHN, Toronto, ON, Canada, ²Krembil Research Institute, UHN, Toronto, ON, Canada, ³Institute of Medical Science, University of Toronto, Toronto, ON, Canada, ⁴Dept. of Laboratory Medicine and Pathobiology Institute, UHN, Toronto, ON, Canada, ⁵Schulich School of Medicine & Dentistry, UWO, London, ON, Canada, ⁶The Hospital for Sick Children Research Institute, Toronto, ON, Canada
*Purpose: Kidneys donated after circulatory death (DCD) contribute significantly to the donor pool, but have inferior outcomes. Normothermic ex-vivo kidney perfusion (NEVKP) results in significantly…
2020 American Transplant Congress
Impact of Donation after Circulatory Death Allografts on Outcomes Following Liver Re-Transplantation in the United States
S. Kumar¹, S. Lin², J. D. Schold²
¹Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, ²Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Scarcity of donor organs in liver transplantation (LT) has necessitated consideration of donation after circulatory death (DCD) donors. Complications following LT and disease recurrence…
2020 American Transplant Congress
Maximizing the Gift: One OPO’s Experience Maximizing the Gift of Organ Donation by Successfully Increasing the Number of Organs Transplanted from Non-Braindead Donors
J. B. Nave, A. J. Boyer, C. A. Hostetler, C. C. Muse, R. A. Squires, J. P. Orlowski
LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK
*Purpose: In 2018 in the United States, donation after circulatory death (DCD) cases accounted for 20% of deceased organ donor recoveries1. Our organ procurement organization's…
2020 American Transplant Congress
Using an Ex Vivo Blood-Free Model of Preservation and Reperfusion to Evaluate the Effects of Subnormothermic Perfusion with Hydrogen Sulfide on DCD Porcine Renal Grafts
S. Juriasingani¹, A. Ruthirakanthan¹, M. Richard-Mohamed², M. Zhang¹, M. Levine¹, E. Sogutdelen¹, M. Mandurah¹, A. Sener¹
¹University of Western Ontario, London, ON, Canada, ²London Health Sciences Centre, London, ON, Canada
*Purpose: The need for donor blood complicates the clinical translation of normothermic and subnormothermic perfusion for preservation and graft function evaluation. As such, hemoglobin-based oxygen…
2020 American Transplant Congress
One Organ Procurement Organization Coordinates 43% of All Uncontrolled Donation after Circulatory Determination of Death Donors Recovered in the United States Over 24 Years
R. D. Hasz, S. M. West, H. M. Nathan
Gift of Life Donor Program, Philadelphia, PA
*Purpose: An IOM report published in 2006 estimated that 22,000 potential uncontrolled Donation after Circulatory Determination of Death (uDCDD) donors die each year in the…
2020 American Transplant Congress
The Negative Impact of Inherent Oxidative Stress in Marginal Lungs on Ex Vivo Lung Perfusion
K. Noda¹, B. J. Philips¹, M. Velayutham², T. Harano¹, P. Reck dos Santos¹, S. Shiva², P. G. Sanchez¹
¹Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, ²Department of Medicine, University of Pittsburgh, Pittsburgh, PA
*Purpose: Identifying good quality grafts within the donor pool, ex vivo lung perfusion (EVLP) opens another window to evaluate grafts initially declined with marginal quality…
2020 American Transplant Congress
Individualized Impact of Donation after Cardiac Death on Kidney Transplant Outcomes
S. Bae, A. Massie, J. Garonzik Wang, D. Segev
Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Increasing the use of kidneys from donation after cardiac death (DCD) donors is a potential solution to mitigate the current organ shortage. However, DCD…

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